ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Diagnosis of Antibody-Mediated Rejection after Kidney Transplantation by Blood Expression of Genes Involved in IFN Signaling

    M. Matz,1 Q. Zhang,1 F. Heinrich,2 C. Lorkowski,1 K. Wu,3 P. Durek,2 N. Lachmann,4 M-.F. Mashreghi,2 K. Budde.1

    1Nephrology, University Medicine Charité Berlin, Berlin, Germany; 2Drfz, Berlin, Germany; 3Pathology, University Medicine Charité Berlin, Berlin, Germany; 4Center For Tumor Medicine, H&I Laboratory, University Medicine Charité Berlin, Berlin, Germany.

    Purpose: Antibody-mediated rejection (ABMR) has been recognized as a major cause of graft loss. Early diagnosis and effective treatment are crucial for salvaging grafts undergoing…
  • 2018 American Transplant Congress

    C1q-Binding Donor-Specific Anti-HLA Antibodies for Clinical Decision Making in Kidney Recipients with Antibody-Mediated Rejection Receiving Standard of Care Treatment

    C. Lefaucheur,1 D. Viglietti,1 Y. Bouatou,1 O. Aubert,1 A. Zeevi,2 A. Loupy.1

    1Paris Translational Research Center for Organ Transplantation, Paris, France; 2University of Pittsburgh Medical Center, Pittsburgh.

    One of the major issues in the clinical management of kidney recipients with ABMR is the lack of early and reliable markers that surrogate long-term…
  • 2018 American Transplant Congress

    Biopsy Correlates of DSA in Antibody-Mediated Rejection: C4d vs Microvascular Inflammation Scores

    C. Harris, L. Anderson, R. Khaim, J. Choudhuri, R. Shapiro, S. Florman, F. Salem, M. Menon.

    Icahn School of Medicine at Mount Sinai, New York, NY.

    Background: The diagnosis of antibody-mediated rejection (AMR) requires the presence of both the histologic features of AMR as well as donor-specific antibodies (DSA). Whether anti-HLA…
  • 2018 American Transplant Congress

    Magnitude of Pre-Biopsy Decline in Renal Function and Its Association with Allograft Rejection

    S. Voora,1 P. Ahearn,1 M. Tavakol,2 K. Johansen,1,3 E. Ku.1

    1Division of Nephrology, UCSF, San Francisco, CA; 2Department of Surgery, UCSF, San Francisco, CA; 3Department of Epidemiology/Biostatistics, UCSF, San Francisco, CA.

    Introduction: Acute rejection is a significant cause of morbidity, and transplant biopsy remains the gold standard for diagnosing rejection. To our knowledge there have been…
  • 2018 American Transplant Congress

    Non Active Desensitization Protocol: Improving Access to Kidney Transplant for Hyperimmunized Patients

    S. Le Bot,1 F. Delbos,2 C. Garandeau,1 S. Malard Castagnet,2 A. Cesbron,2 M. Hourmant.1

    1Nephrology and Transplantation, CHU Hôtel Dieu, Nantes, France; 2Laboratoire HLA, Etablissement Français du Sang, Nantes, France.

    Hyperimmunized patients have a bad access to renal transplantation, despite national priority programs and active desensitization protocols. After having noticed that some HLA antibodies decreased…
  • 2018 American Transplant Congress

    Impact of Pneumocystis Prophylaxis on Incidence of Treated Urinary Tract Infections Following Kidney Transplantation

    S. Sanchez, M. Brokhof, N. Kenyon, C. Varughese, N. Alvey.

    Rush University Medical Center, Chicago, IL.

    Background: Urinary tract infection (UTI) is the most common infectious complication after kidney transplantation resulting in increased morbidity and mortality. Sulfamethoxazole[mdash]trimethoprim (SMX-TMP) is commonly used…
  • 2018 American Transplant Congress

    Cryptococcal Infections in Kidney Transplant Recipients. A Single Center Experience

    M. Radisic,1 N. Pujato,1 A. Dotta,2 R. Livia Franzini,2 M. Bravo,1 L. Rodriguez Rilo,1 C. Giampieri,2 L. Leon,1 M. Rial,1 D. Casadei.1

    1Infectious Diseases, Instituto de Nefrologia de Buenos Aires, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina; 2Kidney Transplantation, Instituto de Nefrologia de Buenos Aires, Ciudad Autonoma de Buenos Aires, Buenos Aires, Argentina.

    Cryptococcal infections are infrequent but a cause of morbidity & mortality in transplant (T) recipients. Best treatment and the need for secondary prophylaxis are still…
  • 2018 American Transplant Congress

    Bariatric Surgery before and after Kidney Transplantation: Long-Term Weight-Loss and Allograft Outcomes

    J. Cohen, M. Lim, C. Tewksbury, S. Torres Landa, J. Trofe-Clark, P. Abt, N. Williams, K. Dumon, S. Goral.

    University of Pennsylvania, Philadelphia.

    Obesity, a critical public health issue affecting >25% of kidney transplant (KTX) candidates, is often a barrier to transplantation. Bariatric surgery is an important tool…
  • 2018 American Transplant Congress

    The Impact of Anticoagulation Therapy Modifications during the Index Hospitalization on Clinical Outcomes in Kidney Transplant Recipients

    J. Hardcopf, H. Meadows, N. Pilch, C. Perez, N. Patel, J. Fleming, H. Corbo, T. Harrison, B. O'Brien, D. DuBay, P. Baliga, D. Taber.

    Medical University of South Carolina, Charleston, SC.

    Background: The aim of this study was to determine whether changing anticoagulation medications during the index admission for kidney transplant (KT) is significantly associated with…
  • 2018 American Transplant Congress

    Impact of Balanced Solutions on Acid Base Disorders during and after Kidney Transplantation

    N. Maillard,2 H. Chraka,1 G. Claisse,2 E. Alamartine,2 S. Molliex,1 C. Mariat.2

    1Département d'Anesthésie Réanimation, CHU Saint Etienne, Saint Etienne, France; 2Service de Néphrologie Dialyse Transplantation Rénale, CHU Saint Etienne, Saint Etienne, France.

    Fluid management of peri operative period of kidney transplantation is crucial to drive volemia, acid/base and electrolyte balance, as renal function is usually absent or…
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