ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Hispanics' Perceptions of Shared Decision Making in the Transplant Context: A Mixed Methods Study

    N. Alhalel,1 J. Caicedo,1 R. Ruiz,2 A. Salazar,2 S. Primeaux,2 E. Gordon.1

    1Northwestern University, Chicago, IL; 2Baylor University Medical Center, Dallas, TX.

    Background: Shared decision making (SDM) has been advocated by health researchers and policy-makers as a model to provide patient-centered care and increase patient knowledge, satisfaction,…
  • 2018 American Transplant Congress

    Mayo Clinic's First Face Transplant: 17 Months On

    H. Amer, S. Jowsey-Gregoire, C. Rosen, R. Razonable, K. Reid, M. Gandhi, L. Ewoldt, B. Edwards, S. Mardini.

    The Essam and Dalal Obaid Reconstructive Transplant Center and the William J von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN.

    Mayo Clinic established a reconstructive transplant program as an extension of clinical practice in 2010. A 31-year-old Caucasian male had significant functional limitations and disfigurement…
  • 2018 American Transplant Congress

    Regulatory Dendritic Cell (DCreg) Cell Infusion in Living Donor Liver Transplantation

    A. Thomson, A. Humar, F. Lakkis, S. Styn, A. Zahorchak, C. Macedo, D. Metes.

    Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.

    Purpose: We have embarked on a first-in-human phase I/II safety and preliminary efficacy trial of donor-derived regulatory dendritic cells (DCreg) in living donor liver transplantation…
  • 2018 American Transplant Congress

    Intravenous Immunoglobulins and Methylprednisolone Stabilizes Renal Allograft Function in the Majority of Patients with C-aABMR

    K. Sablik, M. Clahsen-van Groningen, C. Looman, J. Damman, M. van Agteren, M. Betjes.

    Erasmus Medical Center, Rotterdam, Netherlands.

    BackgroundChronic active antibody mediated rejection (c-aABMR) leads to progressive decline in allograft function and is a major contributor to long-term kidney allograft loss. To date,…
  • 2018 American Transplant Congress

    Alemtuzumab Induction as a Mediator of Nonadherence in Renal Transplantation

    G. Mitro, O. Ekwenna, M. Rees, J. Ortiz.

    University of Toledo College of Medicine, Toledo, OH.

    Introduction: “Non-adherent” (NA) is defined as chronic follow-up absenteeism or medication nonadherence. We aimed to determine whether the single-dosing schedule of Alemtuzumab (Ale) may limit…
  • 2018 American Transplant Congress

    Excellent Long-Term Outcomes with Kidney Transplants from Deceased Donors with Acute Kidney Injury

    G. Dube, S. Husain, D. Cohen, S. Mohan.

    Medicine, Columbia University Medical Center, New York, NY.

    Kidney transplants (KT) from donors with acute kidney injury (AKI; terminal creatinine ≥ 2.0) are increasingly performed and have similar short-term outcomes compared with KT…
  • 2018 American Transplant Congress

    Once-Daily MeltDose Tacrolimus Formulation and Renal Function in Caucasian Fast Tacrolimus Metabolizers: Does Early Identification Have an Impact in PK Sensitive Patients?

    K. Budde,6 B. Suwelack,1 D. Stevens,3 W. Du,4 C. Procaccianti,5 C. Maas,5 S. Bunnapradist.2

    1University Hospital of Münster, Münster, Germany; 2David Geffen School of Medicine at UCLA, Los Angeles; 3Veloxis Pharmaceuticals, Cary; 4Clinical Statistics Consulting, Norrystown; 5Chiesi Farmaceutici S.p.A., Parma, Italy; 6Charité Universitatsmedizin, Berlin, Germany.

    Tacrolimus (TAC) nephrotoxicity can be seen even at low blood trough levels, with factors beyond trough levels potentially contributing. TAC fast metabolizers have higher Cmax,…
  • 2018 American Transplant Congress

    Long-Term Efficacy and Safety of Everolimus Based Immunosuppression on De Novo Kidney Transplantation with 9 Years Follow-Up

    S. Narumi,1 Y. Watarai,1 N. Goto,2 T. Hiramitsu,1 M. Okada,1 M. Tsujita,2 K. Futamura,2 M. Nishihira,3 T. Kobayashi.4

    1Transplant Surgery, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Aichi, Japan; 2Transplant Nephrology, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Aichi, Japan; 3Nephrology, Masuko Memorial Hospital, Nagoya, Aichi, Japan; 4Renal Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.

    Purpose: Long-term efficacy and safety of everolimus (EVR) based immunosuppression for de novo kidney transplant recipient who were involved in A1202 study was evaluated in…
  • 2018 American Transplant Congress

    Effect and Reasons of Rescue Switch to Belatacept among 73 Calcineurin-Inhibitors Treated Kidney Allograft Recipients – A Three Years Retrospective Cohort, Single Center Study

    M. Matignon,1 C. Dudreuilh,1 P. Rémy,1 D. Desvaux,2 P. Grimbert.1

    1Nephrology Transplantation, APHP Henri Mondor, Creteil, France; 2Pathology, APHP Henri Mondor, Creteil, France.

    IntroductionAfter kidney transplantation, long-term immunosuppression with calcineurin inhibitors (CNIs) or mTOR inhibitors (mTORi) leads to adverse effects, such as nephrotoxicity and proteinuria. Currently, available data…
  • 2018 American Transplant Congress

    Prolonged-Release Tacrolimus Dosing in De Novo Kidney Transplantation: Randomized, Open-Label, Pilot Study

    Y. Kim,1 Y. Chiang,2 S. Kim,3 M. Kim,4 S. Park,5 S. Wu,6 K. Horita,7 Y. Nakashima,7 H. Jiang,8 D. Han.1

    1Asan Medical Center, Seoul, Korea; 2Chang Gung Memorial Hospital-Linkou, Taoyuan City, Taiwan; 3Samsung Medical Center, Seoul, Korea; 4Severance Hospital, Seoul, Korea; 5Dongsan Medical Center, Daegu, Korea; 6Tri-Service General Hospital, Taipei City, Taiwan; 7Astellas Pharma, Inc., Tokyo, Japan; 8Astellas Pharma, Inc., Maao, Singapore.

    A multicenter, randomized, open-label, parallel-group, pilot, 52-wk study in Asian countries that assessed renal function, efficacy, and safety of low vs standard-dose prolonged-release tacrolimus (PRT)…
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