Am J Transplant, Volume 18, Suppl 3 Archives - Page 32 of 211 - ATC Abstracts

2018 American Transplant Congress
Protocolar Biopsies in Patients with Subclinical De Novo DSA in Kidney Transplantation
D. Bertrand,¹ M. Jaureguy,² C. Garrouste,³ J. Sayegh,⁴ N. Bouvier,⁵ S. Caillard,⁶ L. Lanfranco,⁷ A. Galinier,⁸ A. François,⁹ F. Hau,¹⁰ I. Etienne,¹ P. Gatault.¹¹
¹Nephrology Kidney Transplantation Dialysis, CHU Rouen, Rouen, France; ²Nephrology Kidney Transplantation, CHU Amiens, Amiens, France; ³Nephrology Kidney Transplantation, CHU Clermont Ferrand, Clermont Ferrand, France; ⁴Nephrology Kidney Transplantation, CHU Angers, Angers, France; ⁵Nephrology Kidney Transplantation, CHU Caen, Caen, France; ⁶Nephrology Kidney Transplantation, CHU Strasbourg, Strasbourg, France; ⁷Nephrology Kidney Transplantation, CHU Brest, Brest, France; ⁸Nephrology Kidney Transplantation, CHU Poitiers, Poitiers, France; ⁹Pathology, CHU Rouen, Rouen, France; ¹⁰EFS Normandie, EFS Normandie, Rouen, France; ¹¹Nephrology Kidney Transplantation, CHU Tours, Tours, France.
De novo donor-specific antibody (DSA) is associated with antibody-mediated rejection (ABMR) and allograft loss. The aim of our study was to examine the histology associated…
2018 American Transplant Congress
Subclass Distribution of DSA Analyzed by Mass Spectrometry Predicts the Risk of Humoral Rejection
V. Pernin,^1,2 N. Bec,³ C. Larroque,³ C. Duperray,² G. Mourad,¹ M. Lequintrec.^1,2
¹Department of Nephrology, Dialysis and Kidney Transplantation, CHU Lapeyronie, Montpellier, France; ²INSERM U1183 Institute for Regenerative Medicine & Biotherapy (IRMB), Montpellier, France; ³Institut de Recherche en Cancérologie de Montpellier (IRCM)- CRLC Val d'Aurelle - Paul Lamarque - INSERM U896, Montpellier, France.
Background :DSA occurrence after kidney transplant is a main risk factor for humoral rejection and graft loss, however graft outcomes after DSA detection is very…
2018 American Transplant Congress
Comparison of C1Q Binding and Flow Cytometric Crossmatch Results Provides an Accurate Evaluation of Hypersensitive Kidney Transplant Patients
E. Eksioğlu-Demiralp,¹ A. Türkmen,² B. Yelken,² S. Görçin,² O. Elbasi,¹ F. Yalçin,³ B. Koçak,² C. Karatas,⁴ M. Tuncer,⁴ M. Altinel.³
¹Tissue Typing and Immunology Laboratory, Memorial Health Group, Istanbul, Turkey; ²Sisli Hospital Transplantation Unit, Memorial Health Group, Istanbul, Turkey; ³Hizmet Hospital Transplantation Unit, Memorial Health Group, Istanbul, Turkey; ⁴Atasehir Hospital Transplantation Unit, Memorial Health Group, Istanbul, Turkey.
Measurement of C1q binding to Donor specific antibodies (DSA) gives transplantation chance to hypersensitive patients having non-binding high amount of anti-HLA antibodies. In our series…
2018 American Transplant Congress
Risk Factors for Graft Failure in Kidney Transplant Recipients with Polycystic Kidney Disease
G. Bhutani, B. Astor, A. Djamali.
University of Wisconsin, Madison.
Background: Polycystic kidney disease (PKD) is the underlying renal disease in 15% of kidney transplant recipients (KTRs) in the US. Post-transplant outcomes and contributing factors…
2018 American Transplant Congress
Anti-IdeS Antibodies in IVIg and Its Effect on IdeS Activity
A. Runström,¹ S. Järnum,¹ S. Jordan,² L. Winstedt,¹ C. Kjellman.¹
¹Hansa Medical AB, Lund, Sweden; ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles.
ObjectiveEvaluate how and why intravenous gamma globulin (IVIg) affects IdeS-cleavage of IgG.IntroductionIgG degrading enzyme of Streptococcus pyogenes (IdeS) cleaves human IgG in two steps, first…
2018 American Transplant Congress
Burden of Primary CMV Infections Remains High Despite Six Months Valganciclovir Prophylaxis in High-Risk Kidney Transplant Recipients
I. Helanterä,¹ F. Ortiz,² R. Loginov,³ L. Mannonen,³ M. Lempinen,¹ I. Lautenschlager.³
¹Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland; ²Nephrology, Helsinki University Hospital, Helsinki, Finland; ³Virology, Helsinki University Hospital, Helsinki, Finland.
A. Prophylaxis has mostly replaced preemptive therapy in CMV seronegative recipients of kidneys from seropositive donors (D+/R-). Primary infections occur commonly even after six months…
2018 American Transplant Congress
Clinical Outcomes of Kidney Transplant Recipients Infected with Hepatitis C Virus and Treated with Direct-Acting Antiviral Therapy
M. Alkadi,¹ E. Abuhelaiqa,¹ M. Derbala,² O. Fituri,¹ J. Mahmoud,³ M. Jarman,³ M. Asim,¹ A. Aziz,¹ A. Nauman,¹ A. Hamdi,¹ Y. Medhat,² S. Al Kaabi,² H. Al-Malki.¹
¹Medicine-Nephrology, Hamad Medical Corporation, Doha, Qatar; ²Medicine-Gastroenterology, Hamad Medical Corporation, Doha, Qatar; ³Surgery-Transplant, Hamad Medical Corporation, Doha, Qatar.
Introduction:Hepatitis C virus (HCV) infection has negative impact on patient and graft survival in kidney transplant recipients. In the past, treatment of HCV infection post…
2018 American Transplant Congress
Outcomes of Transplant Patients with Encapsulating Peritoneal Sclerosis(EPS) Treated with Tamoxifen and Steroids
R. Parthasarathy,¹ T. Fairhead,^1,2 B. McCormick,^1,2 G. Knoll,^1,2 S. Hoar.^1,2
¹Division of Nephrology, The Ottawa Hospital, University of Ottawa, Ottawa, ON, Canada; ²Kidney Research Centre, Ottawa Hospital Research Institute, Ottawa, ON, Canada.
EPS, a severe complication of PD and may present after kidney txp upon discontinuation of PD, a condition known as post-transplantation EPS. TDespite the possible…
2018 American Transplant Congress
Neutrophil-Lymphocyte Ratio(NLR) is Significantly Decreased in Kidney Transplant Patients: Is NLR a Novel Predictor of Cardiovascular Disease in Kidney Transplant Patients?
H. Shirakawa,¹ J. Hasegawa,² A. Ishiwatari,² M. Kono,² S. Wakai.²
¹Urology, Ohkubo Hospital, Shinjuku, Tokyo, Japan; ²Nephrology, Ohkubo Hospital, Shinjuku, Tokyo, Japan.
【Background】The neutrophil-to-lymphocyte ratio (NLR) is a novel simple biomarker of in inflammation. It has emerged as a predictor of poor prognosis in cancer and cardiovascular…
2018 American Transplant Congress
Increased BMI is a Predictor of Early Post-Transplant Cardiac Events and Mortality
A. Mahgoub, S. Jackson, J. Lake, N. Lim.
Medicine, University of Minnesota, Minneapolis, MN; Transplant Information Services/ISR2, Fairview Health Services, Minneapolis, MN.
Background: Cardiac events (CVE) remain a significant source of morbidity in the early post-transplant(post-tx) period despite extensive evaluation prior to liver transplant(LT). It is important…