2018 American Transplant Congress
mRNA Transcript Profiling of 3 Genes in Renal Allograft Biopsies (Bx) Improves Accuracy of Antibody-Mediated Rejection (ABMR) Diagnosis in Transplant Recipients Desensitized with IVIG+Rituximab+Immunoglobulin G-Degrading Enzyme of Streptococcus Pyogenes (IdeS)
Background: Multiple molecular signatures specific to ABMR based on gene expression in renal allograft Bx of transplant recipients were reported. Here we assessed mRNA transcript…2018 American Transplant Congress
Livers from Diabetic Donors Can Safely Be Used in Donation after Circulatory Death Liver Transplantation
Liver grafts from donors with a history of diabetes mellitus (DM) have been associated with reduced graft survival after liver transplantation. Transplantation centers are often…2018 American Transplant Congress
Allogeneic Mesenchymal Stem Cells as Induction Therapy Are Safe and Feasible in Renal Allografts: Pilot Results of a Multicenter Randomized Controlled Trial
Background: Delayed graft function (DGF) and acute rejection lead to adverse effects on graft outcomes. Optimal induction intervention should include both renal structure injury repair…2018 American Transplant Congress
NFkB Inhibitor Improves Glycemic Control after Syngeneic Islet Transplantation by Suppression of Proinflammatory and Apoptotic Gene Expression in a Cerulein-Induced Pancreatitis Model
Total pancreatectomy with islet autotransplantation (TPIAT) is an effective treatment for refractory chronic pancreatitis. Repeated or continuous pancreatitis attack leads islet damage beyond inflamed exocrine…2018 American Transplant Congress
Two Years of the HOPE Act
1United Network for Organ Sharing, Richmond, VA; 2Johns Hopkins University, Baltimore, MD.
The HOPE Act allows research on transplantation of organs from HIV+ donors into patients infected with HIV prior to transplantation. There are 42 kidney and…2018 American Transplant Congress
Potential Living Donors Identified through Social Media
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD.
Purpose: We previously described a smartphone application that harnesses social media to increase potential living donors among kidney and liver transplant candidates. We compared potential…2018 American Transplant Congress
Treatment of Post Transplant Hepatitis C (HCV) with Direct-Acting Antiviral (DAA) Agents May Improve Liver Function but Does Not Lead to an Increase in Liver Rejection
Surgery, Hartford Hospital, Hartford, CT.
Previous studies have suggested that with the use of with (DAA) agents to treat post transplant (HCV), there has been an increased incidence of liver…2018 American Transplant Congress
Survival Rates of Patients with Previous Cardiac Surgery Undergoing Lung Transplant
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH.
Background: Severe heart diseases are traditionally considered a contraindication for Lung transplantation (LTx). There are suggestions that patients with severe heart diseases undergoing LTx will…2018 American Transplant Congress
Selection and Stratification of Anti-HLA-A and HLA-B Sensitized Patients in Pig-to-Human Xenotransplantation
Introduction: Patients with anti-HLA-A and –B antibodies are difficult to match and represent a possible population for inclusion in pig-to-human xenotransplantation clinical trials. Donor specific…2018 American Transplant Congress
Use of HCV Ab+/NAT- Donors in HCV Naïve Renal Transplant Recipients
1Univeristy of Cincinnati Medical Center, Cincinnati, OH; 2The Christ Hospital, Cincinnati, OH.
The continued organ shortage in renal transplantation (RT) has stimulated use of organs from increased-risk donors to expand the donor pool. The rate of denovo…
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