Am J Transplant, Volume 18, Suppl 3 Archives - Page 28 of 211 - ATC Abstracts

2018 American Transplant Congress
Selection and Stratification of Anti-HLA-A and HLA-B Sensitized Patients in Pig-to-Human Xenotransplantation
G. Martens,¹ J. Ladowski,¹ J. Butler,² L. Reyes,¹ M. Tector,¹ A. Tector.¹
¹University of Alabama at Birmingham, Birmingham, AL; ²Indiana University School of Medicine, Indianapolis, IN.
Introduction: Patients with anti-HLA-A and –B antibodies are difficult to match and represent a possible population for inclusion in pig-to-human xenotransplantation clinical trials. Donor specific…
2018 American Transplant Congress
Use of HCV Ab+/NAT- Donors in HCV Naïve Renal Transplant Recipients
A. Dao,¹ M. Cuffy,¹ T. Kaiser,¹ A. Loethen,¹ J. Cafardi,² A. Shields,² M. Cardi,² R. Alloway,¹ A. Govil,¹ K. Sherman,¹ S. Shah,¹ E. Woodle.¹
¹Univeristy of Cincinnati Medical Center, Cincinnati, OH; ²The Christ Hospital, Cincinnati, OH.
The continued organ shortage in renal transplantation (RT) has stimulated use of organs from increased-risk donors to expand the donor pool. The rate of denovo…
2018 American Transplant Congress
Risk Factors for Chronic Opioid Use after Kidney Transplantation
J. Fleming, D. Taber, R. Gilbert, L. Wilson, Z. Elmaasarani, B. O'Brien, N. Patel, N. Pilch, S. Ball, P. Mauldin, P. Baliga.
MUSC, Charleston, SC.
Opioid use is associated with increased complications, graft loss, and mortality in the kidney transplant (KTX) population. The aim of our study was to identify…
2018 American Transplant Congress
Secular Trends in the Medical Complexity and Outcomes of Medicare-Insured Patients Undergoing Kidney Transplant
C. Lenihan,¹ S. Liu,¹ M. Montez-Rath,¹ W. Winkelmayer.²
¹Stanford University, Palo Alto, CA; ²Baylor College of Medicine, Houston, TX.
Graft and patient survival following kidney transplant (KT) are improving. The reasons for this trend are unclear. We set out to examine concurrent changes in…
2018 American Transplant Congress
Anti-TIRC7 Antibody Acts Synergistically with Tacrolimus in Promoting Graft Survival in a Rat Kidney Transplant Model
S. Tullius,¹ Y. Kumamoto,² U. Nalan.³
¹Department of Medicine, Brigham and Women's Hospital, Boston, MA; ²Department of Surgery, Kitasato University School of Medicine, Kanagawa, Sagamihara, Japan; ³Institute for Medical Immunology, University Hospital Charite, Berlin, Germany.
Background: Induction of T cell immune response c-DNA (TIRC7) is restricted to activated lymphocytes. Modulation of TIRC7 signalling prevents immune activation specifically at the site…
2018 American Transplant Congress
Outcomes after HIV+ Kidney Transplant: A HOPE in Action Study
C. Durand,¹ M. Bowring,¹ A. Tobian,¹ D. Brown,¹ N. Desai,¹ S. Bagnasco,¹ D. Ostrander,¹ A. Redd,¹ S. Huprikar,² B. Haydel,² S. Lerner,² S. Florman,² S. Chandran,³ A. Chao,³ J. Locke,⁴ S. Mehta,⁴ R. Freidman,⁵ N. Turgeon,⁵ A. Massie,¹ D. Segev.¹
¹JHU, Baltimore, MD; ²Mount Sinai, New York, NY; ³UCSF, San Francisco, CA; ⁴UAB, Birmingham; ⁵Emory, Atlanta.
The HIV Organ Policy Equity (HOPE) Act allows HIV-infected donor (HIV D+) organs to be transplanted into HIV+ recipients (HIV R+) under research protocols. We…
2018 American Transplant Congress
Extra-Renal Effects of Estrogen Receptor-Alpha Mediate Protection from Renal Ischemia-Reperfusion Injury
D. Aufhauser, D. Murken,¹ S. Concors,¹ Z. Wang,¹ G. Ge,¹ T. Bhatti,² W. Hancock,^2,3 M. Levine.¹
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Pathology, Children's Hospital of Philadelphia, Philadelphia, PA; ³Pathology, University of Pennsylvania, Philadelphia, PA.
Introduction: Females exhibit protection from renal ischemia-reperfusion injury (IRI) compared to males in animal models and in human kidneys transplants. Previous experiments have shown that…
2018 American Transplant Congress
Class II Anti-HLA IgG2 and IgG3 DSAs Predict Poorer Outcomes in Chronic Antibody Mediated Rejection of Renal Allografts
A. Gueret-Wardle,¹ G. Lucisano,¹ S. Hassan,¹ P. Brookes,² E. Santos-Nunez,² D. Goodall,¹ C. Clarke,¹ J. Galliford,¹ M. Willicombe,¹ D. Taube.¹
¹Renal and Transplant Centre, Imperial College London NHS Trust, London, United Kingdom; ²Histocompatibility and Immunogenetics, Imperial College London, London, United Kingdom.
Introduction: whilst the development of IgG3 and C1q binding de novo [dn] HLA DSAs are associated with a poor outcome in acute antibody mediated rejection,…
2018 American Transplant Congress
Effects of a Multimodal Pain Control Regimen in Living Donor Laparoscopic Nephrectomies
E. Thomas, J. Nelson, E. Diaz.
Department of Surgery, University of Florida, Gainesville, FL.
Purpose: Evaluate the effects of a multimodal pain control regimen on length of stay (LOS), opioid consumption, pain control, and opioid/NSAID related adverse events in…
2018 American Transplant Congress
Clinical Implications of Positive Crossmatch in Liver Retransplants
F. Paterno, S. Tremblay, K. Wima, M. Cuffy, T. Diwan, N. Anwar, E. Woodle, S. Shah.
Surgery, University of Cincinnati, Cincinnati, OH.
BackgroundLiver transplant has been performed successfully regardless of a positive crossmatch. However, the clinical implications of a positive crossmatch in liver retransplants have not been…