ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Temporal Trends in Living Kidney Donor Candidates

    S. Singh,1,2 V. DiCecco,2 M. Luo,2 Y. Li,2 O. Famure.2

    1Division of Nephrology, Department of Medicine, University of Toronto, Toronto, ON, Canada; 2Division of Nephrology and the Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.

    Living kidney donor transplantation is the preferred treatment option for end-stage renal disease. However, living kidney donation rates have plateaued in North America. Existing studies…
  • 2018 American Transplant Congress

    Torsion and Inversion of Intraperitoneal Kidneys Manifesting as Acute Allograft Dysfunction – A Case Series

    P. Kandula, A. Patel, S. Bains, H. Sun.

    Saint Barnabas Medical Center, Livingston, NJ.

    Torsion (rotation of kidney allograft around its vascular pedicle) or inversion (rotation of kidney graft around ureter) of intraperitoneal transplant kidney is a rare complication.…
  • 2018 American Transplant Congress

    Prospective Study of Switching from Tacrolimus to Low-Dose Cyclosporine A Preserving Allograft Function in BK Virus-Associated Nephropathy

    G. Huang, X. Chen, S. Yang, C. Wang.

    Organ Transplant Center/Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.

    Background: Tacrolimus(Tac) -mycophenolic acid compared to cyclosporine is an independent risk factor for BK virus-associated nephropathy (BKVAN). Cyclosporine A (CsA) can inhibit BKV replication in…
  • 2018 American Transplant Congress

    Increased Gene Expression of TGF-b in Renal Transplant Patients with Polyomavirus BK Viremia

    W. Yin.

    SURGERY, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Chia I, Taiwan; School of Medicine, Tzu Chi University, Hualien, Taiwan.

    Objective: We aimed to investigate the roles of cytokines during polyomavirus BK (BKV) reactivation in renal transplant patients.Materials and Methods: Fortyeight renal allograft recipients were…
  • 2018 American Transplant Congress

    The Impact of Spontaneous Bacterial Peritonitis on Patient Outcomes after Liver Transplantation Using the Scientific Registry of Transplant Recipient (SRTR) Database

    D. Moonka,1 G. Divine,2 S. Nagai.3

    1Division of Gastroenterology and Hepatology, Henry Ford Health System, Detroit, MI; 2Public Health Sciences, Henry Ford Health System, Detroit, MI; 3Transplant Institute, Henry Ford Health System, Detroit, MI.

    Spontaneous bacterial peritonitis (SBP) is associated with abdominal inflammation and increased morbidity in patients with end-stage liver disease. However, SBP has generally not been associated…
  • 2018 American Transplant Congress

    Surgical Categorization Improve Outcomes and Organ Utilization in Liver Transplant

    H. Bohorquez,1,2 H. Sharma,1 D. Bruce,1 A. Cohen,1,2 C. Carmody,1,2 J. Seal,1 E. Bugeaud,1 D. Sonnier,1 A. Mathur,1 D. Marroquin,1 M. Voltz,1 D. Lucia,1 G. Loss.1,2

    1Multi-Organ Transplant Institute, Ochsner Helath System, New Orleans, LA; 2School of Medicine, University of Queensland, New Orleans, LA.

    Background: Liver transplant (LT) varies greatly in technical complexity due to factors such as prior surgery, obesity, and portal vein thrombosis (PVT). This must be…
  • 2018 American Transplant Congress

    Circulating Exosomes with Lung Self-Antigens, Kα1Tubulin and Collagen V, and Immunoregulatory Molecules Are Present in Bronchiolitis Obliterans Syndrome Following Pediatric Lung Transplantation

    M. Sharma,1 L. Danziger-Isakov,2 P. Heeger,3 S. Sweet,4 T. Mohanakumar.1

    1Norton Thoracic Insitute, St. Joseph's Hosp & Med Ctr, Phoenix; 2Cincinnati Children's Hosp Med Ctr, Cincinnati; 3Icahn Sch Med at Mt Sinai, New York; 4Washington Univ Sch Med, St. Louis.

    Exosomes containing mismatched donor HLA and lung restricted self-antigens (SAgs), Kα1 Tubulin (Kα1T) and Collagen V (Col-V), have demonstrated in sera and bronchoalveolar lavage fluid…
  • 2018 American Transplant Congress

    Efficacy of Bronchoscopically-Administered Surfactant in the Setting of Primary Graft Dysfunction after Lung Transplantation

    S. Ahmed,1 M. Soto-Arenall,1 D. Jackson,1 D. Erasmus.2

    1Department of Pharmacy, Mayo Clinic in Florida, Jacksonville, FL; 2Department of Transplantation, Mayo Clinic in Florida, Jacksonville, FL.

    Primary graft dysfunction (PGD) is a severe form of ischemia and reperfusion acute lung injury presenting within the first 72 hours post-lung transplant. PGD is…
  • 2018 American Transplant Congress

    Activation Requirements of Costimulation Blockade-Resistant CD4 T Cells

    J. Espinosa, B. Adams, J. Kearns, F. Shaw, R. Osborne, T. Woody, M. Ellis, J. Cheeseman, A. Kirk.

    Duke University, Durham.

    T cells lose costimulation dependence following primary activation and many phenotypes of terminally differentiated cells have been identified as contributing to costimulation blockade (CoB)-resistant rejection…
  • 2018 American Transplant Congress

    Immunomonitoring of Operational Tolerance in Intestinal Transplantation

    O. Aguirre, B. Houlihan, T. Fishbein, A. Kroemer.

    Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.

    A. The purpose of this study is to immunocharacterize the first reported case of intestinal transplant (ITx) operational tolerance, in parallel with a stable ITx…
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