2018 American Transplant Congress
Potential Living Donors Identified through Social Media
Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD.
Purpose: We previously described a smartphone application that harnesses social media to increase potential living donors among kidney and liver transplant candidates. We compared potential…2018 American Transplant Congress
Treatment of Post Transplant Hepatitis C (HCV) with Direct-Acting Antiviral (DAA) Agents May Improve Liver Function but Does Not Lead to an Increase in Liver Rejection
Surgery, Hartford Hospital, Hartford, CT.
Previous studies have suggested that with the use of with (DAA) agents to treat post transplant (HCV), there has been an increased incidence of liver…2018 American Transplant Congress
Survival Rates of Patients with Previous Cardiac Surgery Undergoing Lung Transplant
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH.
Background: Severe heart diseases are traditionally considered a contraindication for Lung transplantation (LTx). There are suggestions that patients with severe heart diseases undergoing LTx will…2018 American Transplant Congress
Selection and Stratification of Anti-HLA-A and HLA-B Sensitized Patients in Pig-to-Human Xenotransplantation
Introduction: Patients with anti-HLA-A and –B antibodies are difficult to match and represent a possible population for inclusion in pig-to-human xenotransplantation clinical trials. Donor specific…2018 American Transplant Congress
Donor Derived Renal Cell Carcinoma (RCC) Transmission Events 2008-2016: A Report of the OPTN Disease Transmission Advisory Committee (DTAC)
Background: RCC is the most common renal tumor reported to the OPTN and reviewed by DTAC for assessment of potential donor transmission. Organs with concern…2018 American Transplant Congress
Assessment and Validation of Potential Predictors of Non-Adherence in Contemporary Kidney Transplant Recipients
Medical University of South Carolina, Charleston, SC.
The aim of this study is to assess the associations between traditional proxies of medication non-adherence and graft outcomes in contemporary kidney transplant recipients (KTRs).Methods:…2018 American Transplant Congress
Impact of Elevated PSA, and Prostate Cancer in ESRD on Time to Transplant, and Survival
1University Hospitals of Cleveland, Cleveland, OH; 2Case Western Reserve University, Cleveland, OH.
Introduction: Despite concerns for over-diagnosis and over-treatment from prostate cancer screeening, transplant centers perform it. We studied effect of Elevated PSA, and Prostate cancer on…2018 American Transplant Congress
Combination Proteasome Inhibition and Anti-BAFF Therapy Permits Highly Sensitized Rhesus Kidney Transplantation
Duke Transplant Center, Duke University Medical Center, Durham, NC.
Purpose:HLA-sensitization is a significant immunologic barrier to successful kidney transplantation (KT). We have shown that proteasome inhibition (PI) in insolation reduces plasma cells (PCs), but…2018 American Transplant Congress
CTLA4-Ig and Bortezomib Successfully Reverses Established DSA Responses in Allograft-Sensitized Recipients
Background: Sensitized recipients have lower rates of transplantation and poorer outcomes. We and others have reported that the delayed administration of CTLA4-Ig can disrupt fully-established…2018 American Transplant Congress
Prolonged Cold Ischemia Storage of Renal Allografts Shifts DSA Specificity and Enchances Glomerular Injury
Immunology, Cleveland Clinic, Cleveland, OH.
Prolonged cold ischemia storage (CIS) of donor organs is a major risk factor for acute and chronic graft injury. The goal of this study was…
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