Am J Transplant, Volume 18, Suppl 3 Archives - Page 25 of 211 - ATC Abstracts

2018 American Transplant Congress
Simultaneous Persistence and Development of Donor and Recipient Tissue Resident Memory T Cells in Lung Transplantation
M. Snyder,¹ T. Connors,² C. Marboe,³ L. Benvenuto,¹ L. Shah,¹ H. Robbins,¹ J. Hook,¹ F. D'Ovidio,⁴ M. Bacchetta,⁴ J. Sonnett,⁴ S. Arcasoy,¹ D. Farber.^4,5
¹Medicine, Columbia University Medical Center, New York, NY; ²Pediatrics, Columbia University Medical Center, New York, NY; ³Pathology, Columbia University Medical Center, New York, NY; ⁴Surgery, Columbia University Medical Center, New York, NY; ⁵Microbiology & Immunology, Columbia University Medical Center, New York, NY.
Introduction: The predominant T cell population in the lung comprises non-circulating tissue-resident memory T cells (TRM); however, the fate of these cells in transplanted lung…
2018 American Transplant Congress
Trends of Racial and Education Disparity in Post-Kidney-Transplant Graft Survival and Patient Survival: Do Different Metrics Lead to Different Conclusions?
M. Garber, K. Ross, R. Hamoda, L. Plantinga, R. Patzer.
Emory University, Atlanta.
Background: Monitoring trends in racial and socioeconomic disparity in disease outcomes is a Healthy People 2020 priority. For some chronic disease outcomes, such as cancer…
2018 American Transplant Congress
You've Gotta Have HOPE: Seeking HIV Donors in a Large US OPO
A. Friedman,¹ S. Huprikar,² K. Delli Carpini.¹
¹LiveOnNY, NY; ²Medicine, Mount Sinai School of Medicine, NY.
Passage of the HOPE Act in 2013 led to important workflow changes within a large US organ procurement organization (OPO). The initial triage process for…
2018 American Transplant Congress
Donor Bacteremia Does Not Impact Survival Following Heart Transplantation: A UNOS Registry Review
S. Hirji, A. Woolley, M. Pelletier, P. Shekar, F. Yazdchi, H. Mallidi, S. Singh.
Division of Cardiac Surgery, Brigham and Women's Hospital, Boston, MA.
Background: There is a reluctance to transplant organs from donors who are bacteremic due to concern for transmission of the infection to the recipient leading…
2018 American Transplant Congress
Diagnosis and Prevalence of Strongyloidiasis in Solid Organ Transplant Patients
H. Pritchard,¹ V. Hemmige,¹ R. Mejia,² A. Restrepo.¹
¹Division of Infectious Diseases, Baylor College of Medicine, Houston, TX; ²National School of Tropical Medicine, Baylor College of Medicine, Houston, TX.
Background: Immunosuppression of a host with chronic Strongyloides stercoralis infection can lead to dissemination, with a fatality rate of up to 85%. Screening for S.…
2018 American Transplant Congress
Effects of Preformed Antibody on Survival Following Pig-to-Primate Liver Xenotransplantation
N. Louras, M. Patel, J. Shah, A. Andrews, Z. Wang, D. Sachs, P. Vagefi.
Transplant Surgery, Massachusetts General Hospital, Boston, MA.
Objectives:Xenotransplantation represents the best near-term solution to address the current organ shortage. We have developed a pre-clinical model of pig-to-primate liver xenotransplantation (LXT), and now…
2018 American Transplant Congress
Exenatide Reduces Ischemia/Reperfusion Injury in Donation after Cardiac Death Rat Kidney Transplantation
H. Yang,¹ Y. Shi,² X. Li,¹ C. Long,¹ Z. Xu,¹ L. Luo,¹ W. Luo,¹ Y. Zhang,¹ T. Zeng,³ M. Chen,⁴ H. Li,⁵ Z. Wang.⁵
¹Department of Organ Transplantation, People's Hospital of Jiangxi Province, Nanchang, Jiangxi Province, China; ²Department of Pathology, Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China; ³Department of Urologic Surgery, People's Hospital of Jiangxi Province, Nanchang, Jiangxi Province, China; ⁴Department of Vascular Surgery, People's Hospital of Jiangxi Province, Nanchang, Jiangxi Province, China; ⁵Department of Urologic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China.
Background: Exenatide provide protection against warm Ischemia/Reperfusion Injury (IRI) in the rat heart and kidney. We hypothesized that Exenatide reduces IRI in a rat donation…
2018 American Transplant Congress
Supercooling of Human Livers to Extend the Preservation Time for Transplantation
R. de Vries,^1,2 S. Tessier,^1,2 P. Banik,^1,2 S. Ozer,^1,2 S. Napgal,^1,2 S. Cronin,^1,2 J. Markmann,^1,2 H. Yeh,^1,2 K. Uygun.^1,2
¹Department of Surgery, Massachusetts General Hospital, Boston, MA; ²Center for Engineering in Medicine, Harvard Medical School, Boston, MA.
Introduction: Extending the maximum preservation time of donor organs could dramatically improve the outcome of organ transplantation. Static cold storage (SCS) at +5[deg]C is the…
2018 American Transplant Congress
Shortened Cold Ischemia Time and Reduced Incidence of Delayed Graft Function for Kidney Transplants through Enhanced Tissue Compatibility Testing
I. Helanterä,¹ T. Saarinen,² J. Peräsaari,² M. Lempinen,¹ J. Lauronen.²
¹Transplantation and Liver Surgery, Helsinki University Hospital, Helsinki, Finland; ²Histocompatibility Laboratory, Finnish Red Cross Blood Service, Helsinki, Finland.
A. HLA-typing and prospective leukocyte cross-matching needed for deceased donor kidney transplantation (kTX) may delay the onset of surgery. We compared cold ischemia times (CIT)…
2018 American Transplant Congress
Improvement in Intermediate Graft Survival among Deceased Donor Recipients in the Last Decade Due to Improvements in Outcomes of Higher KDPI Kidney Recipients
D. Keith.
Medicine, Sacred Heart Hospital, Pensacola, FL, Turkey.
Previous research by our group showed that intermediate graft survival of adult deceased donor kidney transplants between six months and three years post-transplant improved in…