Am J Transplant, Volume 18, Suppl 3 Archives - Page 207 of 211 - ATC Abstracts

2018 American Transplant Congress
Critical Care Management of Organ Donors with Uncertain Consent Status
M. Varma, J. LaRosa.
Department of Medicine, Newark Beth Israel Medical Center, Newark, NJ.
Introduction: Donor management is a foundation of organ transplantation. It requires professionalism, compassion, and collaboration between intensive care unit (ICU) staff, organ procurement organizations (OPOs),…
2018 American Transplant Congress
OPTN VCA Waiting List Trends
J. Wainright, C. Wholley, W. Cherikh, J. Musick, D. Klassen.
UNOS, Richmond, VA.
Since the start of the OPTN VCA waiting list (WL), 49 candidates– 53.1% male, 81.6% white, & 75.5% <45 yrs – were added to the…
2018 American Transplant Congress
Successful Patency in Blood Conduits for an Artificial Kidney Membrane with Biocompatible Coatings
R. Forbes,¹ E. Marsh,¹ S. Karp,¹ A. Buck,¹ D. Colvin,¹ P. Williams,¹ B. Chaudhuri,² S. Roy,² W. Fissell.¹
¹VUMC, Nashville; ²UCSF, San Francisco.
BACKGROUND: An implantable artificial kidney may address the growing organ shortage and improve outcomes and quality of life for those with end stage renal disease.…
2018 American Transplant Congress
Reassessment of Virtual Crossmatch: The Clinical Meaning of Cell-Based Actual Crossmatch for Kidney Transplantation
B. Peng,^1,2 M. Yu,^1,2 Q. Zhuang,^1,2 H. Liu,^1,2 L. Zhu,^1,2 Y. Liu,^1,2 K. Cheng,^1,2 Y. Ming.^1,2
¹Transplantation Center, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China; ²Engineering & Technology Research Center for Transplantation Medicine, National Ministry of Health, Changsha, Hunan, China.
Background: Due to the high sensitivity and specificity of Luminex technique, the Luminex single antigen beads (LSAB) assays are widely used in detecting the HLA…
2018 American Transplant Congress
Searching for Recipient-HLA Class II and Donor-HLA-Derived Peptide Complexes Inducing Protective Effect against De Novo Donor-Specific HLA Antibodies Formation in Kidney Transplantation
T. Tomosugi,¹ K. Iwasaki,¹ M. Okumura,¹ Y. Matsuoka,¹ K. Horimi,¹ M. Okada,² Y. Watarai,² T. Kobayashi.¹
¹Kidney Transplant Surgery, Aichi Medical University, Nagakute, Aichi, Japan; ²Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Aichi, Japan.
De novo donor-specific HLA antibodies (dnDSA) are recognized as a risk factor for late deterioration of renal allograft function. dnDSA production occurs via the indirect…
2018 American Transplant Congress
Aggressive Pursuit of Donation after Cardiac Death Kidney Donors with High Kidney Donor Profile Index: Good Use of Resources?
J. Rogge, C. Hostetler, B. Nicely, S. Rudich.
Clinical Division, Gift of Life Michigan, Ann Arbor, MI.
Pursuit of donation after cardiac death (DCD) organ donors requires a significant investment in resources. As an Organ Procurement Organization which very aggressively pursues such…
2018 American Transplant Congress
Effect of De Novo Use of Everolimus with Reduced Calcineurin Inhibitor versus Standard Mycophenolic Acid-Based Regimen on Wound Healing Events in Kidney Transplant Recipients from TRANSFORM Study
M. Henry, F. Citterio, M. Kim, D. Kim, P. Bernhardt, A. Gupta, Y. Watarai.
TRANSFORM Study Group, Novartis Pharma AG, Basel, Switzerland.
Purpose: Anti-proliferative properties of mammalian target of rapamycin inhibitors (mTORi) may affect the wound healing process and there are some reservations about including mTORi into…
2018 American Transplant Congress
The Ratio of CTLA4 to Perforin and Granzyme B as a Potential Biomarker of Tolerance in Chimeric Renal Transplant Patients
A. Khalil,¹ A. Chhabra,¹ A. Merchak,¹ L. Kahn,¹ J. Leventhal,² S. Ildstad.¹
¹Institute for Cellular Therapeutics, University of Louisville, Louisville, KY; ²Northwestern University, Chicago, IL.
Background: Thirty-six subjects have been enrolled in a phase II clinical trial aimed to induce tolerance through chimerism. Each subject received FCRx (mPBMC enriched in…
2018 American Transplant Congress
Evaluation of Multiple Linear Regression Limited Sampling Strategies for Enteric-Coated Mycophenolate Sodium in Adult Kidney Transplant Recipients
C. Staatz,¹ E. Brooks,¹ N. Isbel,² B. McWhinney,³ S. Tett.¹
¹Pharmacy, University of Queensland, Brisbane, QLD, Australia; ²Department of Nephrology, Princess Alexandra Hospital, Brisbane, QLD, Australia; ³Department of Pathology, The Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia.
Background: Although multiple linear regression-based limited sampling strategies (LSS) have been published for enteric-coated mycophenolate sodium none have been evaluated for prediction of subsequent mycophenolic…
2018 American Transplant Congress
Calcineurin Inhibitors, Macrolides, and the Risk of Adverse Drug Events in Kidney Transplant Recipients
R. Jeong,¹ R. Quinn,² P. Ravani,² K. Lentine,³ A. Lloyd,¹ B. Hemmelgarn,² K. Wen,¹ B. Braam,¹ S. Gourishankar,¹ A. Wong,¹ N. Lam.¹
¹Univ of Alberta, Edmonton, Canada; ²Univ of Calgary, Calgary, Canada; ³Saint Louis Univ, St. Louis.
Background: After kidney transplantation, calcineurin inhibitors (CNIs, cyclosporine, tacrolimus) are key components of immunosuppression but have multiple potential drug interactions. Macrolide antibiotics are often used…