Am J Transplant, Volume 18, Suppl 3 Archives - Page 207 of 211 - ATC Abstracts

2018 American Transplant Congress
Follow-Up and Outcomes of Epstein-Barr Virus Negative Recipients after a Kidney Transplant from an Epstein-Barr Virus Positive Donor
C. Dudreuilh, E. Asgari, R. Hilton.
Departments of Nephrology and Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
Introduction: Post-transplant lymphoproliferative disorder (PTLD) is one of the most serious complications of chronic immunosuppression after an organ transplant. One of the major risk factors…
2018 American Transplant Congress
Functional Reconstruction of Urogenital Tissue Defects Using VCA: A Novel Microsurgical Penis Transplant Model and Clinical & Histological Rejection Classification
S. Fidder,^1,4 G. Furtmüller,¹ B. Simons,² B. Kern,¹ D. Lough,¹ B. Oh,¹ M. Chicco,¹ C. Brayton,³ W. Lee,¹ D. Cooney,¹ R. Redett,¹ G. Brandacher.¹
¹Dept of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore; ²Dept of Urology, JHU SOM, Baltimore; ³Dept of Molecular & Comparative Pathobiology, JHU SOM, Baltimore; ⁴Plastic and Reconstructive Surgery, Erasmus University Medical Center, Rotterdam, Netherlands.
Background: Defects of male urogenital structures subsequent to major trauma are associated with severely reduced function and quality-of-life. As of recent, penis transplantation represents an…
2018 American Transplant Congress
Dual Function of IRF1/IRF4 on Dendritic Cells in Mouse Liver Transplantation Model
G. Gu, T. Lu, N. Xu, Q. Xia.
Department of Liver Surgery, Renji Hospital, Affiliated by Shanghai Jiaotong University School of Medicine, Shanghai, China.
Tolerogenic dendritic cells play an essential role in transplant tolerance induction. However, how to induce tolerogenic dendritic cells is not fully understood. Here, we sorted…
2018 American Transplant Congress
Scoring Transplant Glomerulopathy Using Morphometry: Correlation with Banff Criteria
M. Morales, A. Denic, W. Park, B. Smith, M. Alexander, M. Stegall.
William J.von Liebig Transplant Center, Mayo Clinic, Rochester, MN.
Background: Transplant glomerulopathy (TG) is a prognostic marker for graft survival. Still, scoring TG using the Banff cg-score remains a challenge and no assessments in…
2018 American Transplant Congress
Liver Transplant Recipients with End-Stage Renal Disease Largely Benefit from Kidney Transplantation
W. Ju, Y. Tang, Q. Zhao, L. Jing, S. Huang, Z. Zhu, F. Ji, Z. Zhang, X. He, G. Chen, Z. Guo, D. Wang.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Background: The incidence of end-stage renal disease (ESRD) following liver transplant (LT) has increased. The actual benefit of kidney transplantation (KT) is not completely understood…
2018 American Transplant Congress
Impact of Elderly Donor Obesity on Long-Term Outcomes in Renal Transplant Recipients
M. Yamada,¹ R. Jandarov,² T. Kaur,¹ S. Shah.¹
¹Nephrology, University of Cincinnati, Cincinnati, OH; ²Environmental Health, University of Cincinnati, Cincinnati, OH.
Background: There has been a dramatic increase in obesity in the United States. Due to longer waiting times, utilization of kidneys from older donors has…
2018 American Transplant Congress
Validation of Genetic Variants Identified in GWAS for Tacrolimus Troughs
P. Jacobson,¹ D. Schladt,² W. Guan,³ J. van Setten,⁶ R. Remmel,⁴ B. Wu,³ C. Dorr,⁵ B. Keating,⁷ D. Ikle,⁹ R. Mannon,¹⁰ A. Matas,⁸ A. Israni,⁵ W. Oetting.¹
¹Experimental and Clinical Pharmacology, Univ of MN, Minneapolis, MN; ²Chronic Disease Research Group, Minneapolis Medical Research Foundation, Hennepin County Medical Center, Minneapolis, MN; ³Division of Biostatistics, Univ of MN, Minneapolis, MN; ⁴Medicinal Chemistry, Univ of MN, Minneapolis, MN; ⁵Medicine, Hennepin County Medical Center, Minneapolis, MN; ⁶Cardiology, University Medical Center Utrecht, Utrecht, Netherlands; ⁷Surgery, Univ of Pennsylvania, Philadelphia, PA; ⁸Surgery, Univ of MN, Minneapolis, MN; ⁹Rho Inc, Chapel Hill, NC; ¹⁰Department of Medicine and Surgery, Univ of Alabama, Birmingham, AL.
Purpose: Tacrolimus (TAC) is a substrate for CYP3A4/5 enzymes. It is well-known that variants in these genes are associated with variability in TAC trough concentrations.…
2018 American Transplant Congress
Belatacept and Tacrolimus Corticosteroid-Free Regimens Lead to Elevated Mycophenolic Acid Exposure at 1 and 3 Months after Kidney Transplantation
A. Dao, S. Tremblay, A. Shields, A. Loethen, B. Abu Jawdeh, T. Diwan, A. Govil, E. Woodle, R. Alloway.
UCincinnati, Cincinnati.
Mycophenolate mofetil (MMF) is generally administered as a fixed dose. Studies have shown a relationship between MPA exposure (MPAAUC) but no data evaluates this relationship…
2018 American Transplant Congress
Immunosuppression Does Not Affect Adverse Pathological Outcomes in Men Who Underwent Radical Prostatectomy
M. Eltemamy, A. Elshafei, Y. Nyame, A. Crane, A. Wee, V. Krishnamurthi, E. Klein, S. Jones.
Cleveland Clinic, Cleveland.
Introduction: The impact of imuunosuppression (IS) on biological aggressiveness of cancer prostate (PCa) is unclear. We aim to assess the adverse pathological (AP) outcomes in…
2018 American Transplant Congress
Racial/Ethnic Disparities in Living Donor Kidney Transplantation before and after the New National Kidney Allocation System
X. Zhang,¹ T. Melanson,² L. Plantinga,^3,6 M. Basu,¹ S. Pastan,^1,7 S. Mohan,^4,5 M. Garber,⁶ R. Patzer.^1,6,7
¹Department of Surgery, Emory University School of Medicine, Atlanta; ²Department of Health Policy & Management, Emory University, Atlanta; ³Department of Medicine, Emory University School of Medicine, Atlanta; ⁴School of Medicine, Columbia University, New York; ⁵Department of Epidemiology, Columbia University, New York; ⁶Department of Epidemiology, Emory University, Atlanta; ⁷Emory Transplant Center, Emory Healthcare, Atlanta.
We aimed to assess the potential unintended impact of a new national kidney allocation system (KAS) in December 2014 on living donor kidney transplant (LDKT)…