Am J Transplant, Volume 18, Suppl 3 Archives - Page 192 of 211 - ATC Abstracts

2018 American Transplant Congress
Ex Vivo-Expanded Human CD19⁺CD73^–CD25⁺CD71⁺TIM-1⁺ B Regulatory Cells Can Prolong Allograft Survival in a Humanized Mouse Model of Skin Transplantation and Are Dependent on TIM-1-Mediated Regulation of STAT3 Signaling
S. Shankar,¹ J. Stolp,^1,2 S. Juvet,^1,3 J. Hester,¹ K. Wood.¹
¹Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom; ²Garvan Institute of Medical Research, Sydney, Australia; ³Toronto General Hospital Research Institute, Toronto, Canada.
The importance of B regulatory cells (Breg) in both health and disease has rapidly become evident over the last decade. Breg are able to control…
2018 American Transplant Congress
Outcome of Second Kidney Transplantation According to Previous Pediatric Donor Type: A Retrospective Cohort Analysis
K. Phonphok, T. Duong, S. Panombualert, S. Bunnapradist.
Medicine-Nephrology, UCLA, Los Angeles, CA.
Background: With the prioritization of age ≤ 18 years old at the time of registration on the kidney transplant waiting list in the United States,…
2018 American Transplant Congress
Dialysis Modality, Inflammation, and Frailty in Kidney Transplant Candidates
P. Shrestha, H. Ying, M. McAdams DeMarco, D. Segev.
JHU, Baltimore, MD.
Inflammation is associated with poor physical performance, frailty, disability and death in community-dwelling older adults. Given the elevated inflammation levels among ESRD patients, it is…
2018 American Transplant Congress
The Feasibility of Laparoscopic Living Donor Right Hepatectomy Compared to Open Surgery Including 100 Laparoscopic Cases
J. Rhu, G. Choi, J. Kim, J. Joh, C. Kwon, S. Kim.
Department of Surgery, Samsung Medical Center, Seoul, Republic of Korea.
Background: We designed this study to analyze the feasibility of laparoscopic living donor hepatectomy by comparing to open living donor hepatectomy.Methods : Living donors who…
2018 American Transplant Congress
Heart and Lung Transplantation Outcomes in HIV-Positive Recipients
C. Koval,¹ M. Malinis,² N. Mueller,³ J. Krisl,⁴ M. Hannan,⁵ P. Grossi,⁶ S. Huprikar.⁷
¹Infectious Diseases, Cleveland Clinic, Cleveland, OH; ²Infectious Diseases, Yale University, New Haven, CT; ³Infectious Diseases, University Hospital Zurich, Zurich, Switzerland; ⁴Pharmacy, Houston Methodist Hospital, Houston, TX; ⁵Infectious Diseases, Mater Hospital, Dublin, Ireland; ⁶Infectious Diseases, University Insubria, Varese, Italy; ⁷Infectious Diseases, Mount Sinai Hospital, New York, NY.
Purpose: Data for HIV+ patients receiving heart (HT) or lung transplantation (LT) are limited but appear to demonstrate acceptable outcomes. We aimed to add to…
2018 American Transplant Congress
Medication Reconciliation in Abdominal Transplantation
S. Todd,¹ J. Perryman,² R. Subramanian,² A. Patel,² M. Hawthorne,² R. Buenvenida,² K. Lee,² W. Allison,² D. Lo,² P. Reshamwala.²
¹Department of Pharmacy, Emory University Hospital, Atlanta, GA; ²Emory Transplant Center, Emory University Hospital, Atlanta, GA.
Medication adherence post transplantation is vital. Upon discharge, abdominal transplant patients receive a medication list from the electronic medical record (EMR) and obtain a medication…
2018 American Transplant Congress
Interim Results of the kSORT in the SAILOR Randomized Multicenter Trial
P. Lindner,¹ A. Shroeder,² J. Ekberg,¹ S. Hsieh,² P. Towfighi,² I. Damm,² T. Sigdel,² M. Sarwal.²
¹Sahlgrenska University Hospital, Göteborg, Sweden; ²UCSF, San Francisco.
Background: In a randomized multicenter trial of 222 renal tx recipients treated with steroid minimization and a tacrolimus, MMF based regimen, a novel gene expression…
2018 American Transplant Congress
Evaluation of FlowDSA Crossmatch for Detection of Donor-Specific HLA Antibodies
J. Lee, J. Ryu, A. Choi, E-.J. Oh.
Laboratory Medicine, Seoul St. Mary's Hospital, the Catholic University of Korea, Seoul, Republic of Korea.
Background: Donor-specific HLA antibodies (DSA) are detected by different crossmatch techniques. Flow cytometric crossmatching (FCXM) is sensitive method, but it is subject to false (+)…
2018 American Transplant Congress
Assessment of Immune Cell Profiles in HLA-Sensitized (HS) & Non-HS Patients (Pts) with End Stage Renal Disease (ESRD)
S. Ge,¹ M. Chu,¹ E. Ortiz,¹ A. Vo,² D. Lovato,¹ S. Jordan,² M. Toyoda.¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: Chronic inflammation is often seen in pts w/ ESRD. HLA-sensitization may create or be driven by the cytokines responsible for chronic inflammation. Here we…
2018 American Transplant Congress
Sensing T Cell Killing Activity with Granzyme B Activity Probes
Q. Mac,¹ D. Mathews,² J. Kahla,¹ C. Stoffers,¹ O. Delmas,¹ B. Holt,¹ A. Adams,² G. Kwong.¹
¹Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA; ²Department of Surgery, Emory University School of Medicine, Atlanta, GA.
Purpose: We developed activity-based probes that sense Granzyme B (GzmB) activity during alloreactive T cell killing of donor cellsMethods: FITC-labelled GzmB substrate (IEFDSG) was synthesized…