Am J Transplant, Volume 18, Suppl 3 Archives - Page 189 of 211 - ATC Abstracts

2018 American Transplant Congress
Sub-Clinical Acute Rejection (subAR) Detected by Both Surveillance Biopsy (SBx) and a Peripheral Blood Molecular Biomarker Correlates with De Novo Donor Specific Antibody (dnDSA) Following Kidney Transplant (KT)
R. Heilman,¹ J. Friedewald,² K. Kurian,⁵ T. Whisemant,⁵ E. Poggio,³ C. Marsh,⁵ P. Baliga,⁷ N. Bridges,⁴ J. Odim,⁴ M. Brown,⁴ D. Ikle,³ B. Armstrong,³ L. Zhao,² D. Salomon,⁵ M. Abecassis.²
¹Mayo Clinic, Phoenix; ²Northwestern University, Chicago; ³Rho Federal Systems, Chapel Hill; ⁴National Institute of Allergy and Infectious Disease, Bethesda; ⁵Scripps Health, La Jolla; ⁶Cleveland Clinic, Cleveland; ⁷Medical University of South Carolina, Charleston.
AIMWe investigated the correlation between subAR diagnosed by SBx or by a newly-defined biomarker, and the development of dnDSA.METHODS307 KT patients enrolled into a multi-center…
2018 American Transplant Congress
Donor Plasma Mitochondrial DNA Predicts Post-Transplant Renal Allograft Outcomes
F. Han,¹ S. Wan,² N. Chen,² L. Zheng,³ N. Zhang,⁴ Q. Sun,¹ H. Li,¹ Z. Huang,¹ L. Hong,¹ Q. Sun.¹
¹Kidney Transplantation, Sun Yat-sen University, Guangzhou, China; ²Laboratory of Cancer Biomarkers and Liquid Biopsy, Henan University, Henan, China; ³Department of Medical Statistics and Epidemiology, Sun Yat-sen University, Guangzhou, China; ⁴Department of Pathology, Sun Yat-sen University, Sun Yat-sen, China.
The lack of an accurate biomarker makes it difficult to determine whether an organ is acceptable for transplantation. Mitochondrial DNA (mtDNA) correlates with tissue damage…
2018 American Transplant Congress
Outcomes after Kidney Transplantation in Patients with AL Amyloid Following Autologous Stem Cell Transplantation
V. Gutgarts,^1,2 I. Jaffer Sathick,² C. Rosenbaum,³ T. Muthukumar,¹ H. Hassoun,⁴ C. Flombaum,² H. Landau.⁴
¹Nephrology, Weill Cornell, NY; ²Renal Medicine, Memorial Sloan Kettering, NY; ³Hematology, Weill Cornell, NY; ⁴Hematology, Memorial Sloan Kettering, NY.
BackgroundAL amyloidosis results in kidney failure in about 15-30% of patients and is considered a relative contraindication for kidney transplantation. There is limited data on…
2018 American Transplant Congress
Improved Value with Individualized Antithymocyte Globulin Dosing Protocol in Renal Transplant
J. Dann, W. Ally, M. Bradley, J. Geyston, A. Agarwal.
University of Virginia Healthsystem, Charlottesville, VA.
Medication costs represent one of the largest costs associated with transplantation. With growing pressure to reduce health care costs while maintaining excellent outcomes, this study…
2018 American Transplant Congress
Long Term Outcomes of a Steroid Free, Low Dose Tacrolimus with Everolimus Regimen in Kidney Transplant
Y. Kassis,¹ S. Park,¹ A. Shetty,¹ J. Leventhal,¹ V. Mas,² L. Gallon.¹
¹Comprehensive Transplant Center, Northwestern University, Chicago, IL; ²Department of Surgery, University of Virginia, Charlottesville, VA.
Tacrolimus (Tac) is the most effective immunosuppressive agent to prevent acute allograft rejection. However, long-term transplant (Tx) outcomes are limited, at least in part, by…
2018 American Transplant Congress
A Novel Protocol to Improve Kidney Transplant Outcomes in Patients with Renal Disease Due to Amyloidosis
A. Langone, B. Concepcion, D. Slosky, R. Cornell, S. Horst, S. Goodman.
Vanderbilt University Medical Center, Nashville, TN.
In 2011, members from 10 different medical disciplines formed the Vanderbilt Amyloid Multidisciplinary Program (VAMP) in an effort to improve regional recognition of this rare…
2018 American Transplant Congress
Positive Implications of an Enhanced Recovery after Surgery Protocol Using Liposomal Bupivacaine for Transverse Abdominis Plane Block in the Perioperative Phase of Robotic Assisted Laparoscopic Living Donor Nephrectomy
A. Nickkholgh,¹ A. Agarwal,¹ B. Sarosiek,² A. Sites,³ A. Nishio Lucar,⁴ J. Oberholzer,¹ P. Amato.⁵
¹Dept. of Surgery, University of Virginia Health System, Charlottesville, VA; ²ERAS Program, University of Virginia Health System, Charlottesville, VA; ³Strickler Transplant Institute, University of Virginia Health System, Charlottesville, VA; ⁴Dept. of Internal Medicine, University of Virginia Health System, Charlottesville, VA; ⁵Dept. of Anesthesiology, University of Virginia Health System, Charlottesville, VA.
Introduction. Enhanced Recovery After Surgery (ERAS) protocols aim to mitigate the physical and psychological stress response to surgery. Postop pain can increase the need for…
2018 American Transplant Congress
Attitudes of African Canadian Patients with End Stage Kidney Disease toward Living Donor Kidney Transplantation
V. Gupta, C. Richardson, D. Belenko, N. Singh, A. Xu, P. Thiagalingam, D. Wong, H. Ford, M. Novak, I. Mucsi.
University Health Network, Toronto, ON, Canada.
Background:African Canadian patients with end stage kidney disease (ESKD) are less likely to receive a living donor kidney transplant (LDKT) compared to Caucasian Canadians. We…
2018 American Transplant Congress
An Initial Experience with the Endowrist Robotic Endostapling Device for Renal Donor Nephrectomy
M. Tan, H. Pollinger.
Piedmont Transplant Institute, Atlanta.
Introduction:Robot assisted donor nephrectomy has been used an advancement to standard laparoscopic techniques. However, limitations in available instrumentation reduce the efficiency of the procedure especially…
2018 American Transplant Congress
Involvement of Additional Surgeons in Robot Assisted Kidney Transplantation Does Not Affect Surgical Outcomes, in the Context of a Structured Robotic Surgery Program. Results from a CUSUM Analysis
F. Gheza,¹ C. Di Bella,¹ P. Giulianotti,¹ J. Oberholzer,² E. Benedetti,¹ I. Tzvetanov.¹
¹Surgery, University of Illinois, Chicago, IL; ²Surgery, University of Virginia, Virginia, VA.
Robot assisted kidney transplant (RAKT) is a good option for obese recipients. Our group first performed this procedure in 2009 and nowadays the experience includes…