2018 American Transplant Congress
Ex Vivo Lung Perfusion Using the Portable OCS Maintains Endothelial Integrity in the Context of Reduced Severe PGD Rates
PurposeThe INSPIRE trial revealed significant reduction of PGD grade 3, i.e. less ischemia reperfusion injury (IRI) using the Organ Care System (OCS) compared to controls…2018 American Transplant Congress
Endothelial Progenitor Cell-Derived Extracellular Vesicles Inhibit Kidney Ischemia-Reperfusion Injury through the Transfer of Specific microRNA and mRNA Coding for the Complement Inhibitors CD55, CD59, Factor H and for the Transcription Factor NRF2: Relevance for Delayed Kidney Graft Function
Complement activation and oxidative cell damage are hallmarks of delayed kidney graft function (DGF) due to ischemia-reperfusion injury (IRI). Endothelial progenitor cells (EPC) protect from…2018 American Transplant Congress
An Integrative Approach for the Assessment of Peritubular Capillaritis Extent and Score in Microvascular Inflammation – Association with Transplant Glomerulopathy and Graft Loss
Background:Banff Classification accepts two histomorphological features as surrogates of HLA Antibody-Antigen interaction on renal endothelium: C4d staining and microvascular inflammation scores (MVI sum score:ptc+g≥2) which…2018 American Transplant Congress
Clinical Response to Salvage Bortezomib Therapy for Antibody Mediated Rejection and Mixed Acute Rejection in a High Immunologic Risk Renal Transplant Population
University of Illinois at Chicago, Chicago, IL.
Background: Proteasome inhibitor (PI) containing regimens treat antibody mediated rejection (AMR) and mixed acute rejection (MAR) due to elimination of donor specific antibody (DSA). Commonly,…2018 American Transplant Congress
The Promising Approach in Difficult Atypical Hemolytic Uremic Syndrome Series in Renal Transplantation
BACKGROUND:Atypical hemolytic-uremic syndrome (aHUS) belongs to the group of thrombotic microangiopathies (TMAs), which can recur after renal transplantation if they have been identified as the…2018 American Transplant Congress
Glucocorticoid Receptor Polymorphism Affects Susceptibility of Dyslipidemia in Recipients One Year after Kidney Transplantation
Purpose. Dyslipidemia (DL) is a critical comorbidity after renal transplantation and can arise cardiovascular diseases. The relationship between developing of DL and glucocorticoid receptor (NR3C1)…2018 American Transplant Congress
HLA Desensitization Using Rituximab/ Immunoadsorption before Kidney Transplantation
Nephrology, Hemodialyis, Apheresis and Transplantation, CHU Grenoble-Alpes, Grenoble, France.
Introduction: Many kidney-transplant (KT) candidates are sensitized against HLA-antigens, making it difficult to find a suitable HLA-compatible donor. Pretransplant HLA-desensitization strategies have shown improved patient…2018 American Transplant Congress
Recovery of Wild-Type Genotype after Documented Ganciclovir-Resistance in Transplant Recipients with Recurrent CMV Viremia
Purpose: Ganciclovir-resistant cytomegalovirus (GR-CMV) is serious complication after transplantation. Recurrence after primary GR-CMV infection is common, with literature defined rates of approximately 20-30%. It is…2018 American Transplant Congress
Single-Center Experience with Sofosbuvir-Based HCV Treatment after Kidney Transplantation
Nephrology and Kidney Transplant Department, ISCMPA, Porto Alegre, Brazil.
Chronic hepatitis C (HCV) infection is an important clinical challenge after kidney transplantation. This is the initial report of a single-center experience with sofosbuvir-based HCV…2018 American Transplant Congress
The Implications of Impaired Glucose Tolerance after Kidney Transplantation
Background: Post-transplantation diabetes mellitus (PTDM) is highly prevalent after kidney transplantation and associated with significant morbidity. Routine utilization of screening oral glucose tolerance tests (OGTT)…
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