ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Multi-Targeting Desensitization Therapy Alters Peripheral B-Cell Homeostasis and Suppresses Recall Alloantibody Responses

    I. Kim, G. Wu, N-.N. Chai, A. Klein, S. Jordan.

    CTC/Surgery, Cedars-Sinai Medical Center, Los Angeles, CA.

    Purpose: Occurring of donor specific antibodies (DSA) is injurious to organ transplant. Development of immunotherapies to suppress DSA, therefore, has been one of the strategic…
  • 2018 American Transplant Congress

    Pharmacologic Donor Management Influences Liver Transplant Graft Survival and Transplant Admission Length of Stay: An Update

    J. Brandenberger,1 J. Perkins,2 A. Cantafio,3 A. Dick,2 J. Halldorson,4 J. Reyes.2

    1General Surgery; Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, WA; 2Division of Transplant Surgery, University of Washington, Seattle, WA; 3Division of Transplant Surgery, University of Tennessee Medical Center, Knoxville, TN; 4Division of Transplant Surgery, UCSD, San Diego, CA.

    In liver transplantation, donor management is an area that can be modified to improve survival and lower cost. We reviewed the UNOS Standard Transplant Analysis…
  • 2018 American Transplant Congress

    Characterization of Mesenchymal Stem Cell Phenotype and Its Immunomodulatory Effects during Allo-Specific T Cell Immune-Responses

    Q. Gao, A. Kirk, H. Xu.

    Department of Surgery, Duke University Medical Center, Durham, NC.

    Mesenchymal stem cells (MSCs) have been suggested play an important role in modulating cell-mediated immunity. In the setting of transplantation, allogeneic MSCs could mediate suppressive…
  • 2018 American Transplant Congress

    The Impact of Pre-Operative Opioid Use on Delayed Graft Function in Adult Kidney Transplant Recipients

    N. Patel, B. O'Brien, D. Taber, N. Pilch, P. Baliga, Z. Elmaasarani, S. Ball, P. Mauldin, L. Wilson, R. Gilbert, J. Fleming.

    MUSC, Charleston, SC.

    Background and Objectives: Opioid use is associated with AKI and ATN through both direct and indirect mechanisms, including alterations in the autonomic nervous system, the…
  • 2018 American Transplant Congress

    Does Pre-Operative Angiographic Kidney Embolization Decrease Complications in Allograft Nephrectomy?

    D. Harriman, V. Mujumdar, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, R. Stratta.

    Surgery, Medicine, Wake Forest Baptist Health, Winston-Salem, NC.

    Introduction: Morbidity associated with allograft nephrectomy (AN) for treatment of failed or diseased kidney transplants is well documented. Pre-operative angiographic kidney embolization (PAKE), which induces…
  • 2018 American Transplant Congress

    Urinary Microbiome Associated with Chronic Allograft Dysfunction in Kidney Transplants

    A. Israni,1,2 A. Muthusamy,2 B. Wu,3 B. Guo,3 D. Knights,4 G. Al-Ghalith,4 J. Wu,1 W. Oetting,5 D. Schladt,2 R. Remmel,5 P. Jacobson,5 For DeKAF Genomics & GEN03 Investigators.1

    1Medicine, Hennepin County Medical Center, University of Minnesota (UMN), Minneapolis; 2Minneapolis Medical Research Foundation, Mpls; 3Biostatistics, UMN, Mpls; 4Computer Science, UMN, Mpls; 5College of Pharmacy, UMN, Mpls.

    Background: Microbiome dysbiosis can lead to poor outcomes after kidney transplant (tx) presumably due to immune dysregulation elicited by the microbiome. We hypothesize that chronic…
  • 2018 American Transplant Congress

    Association of Physical Function and Survival in Elderly Renal Transplant Recipients

    A. Brar,1 F. Tedla,1 M. Salifu,1 R. Gruessner,2 D. John,2 N. Sumrani,2 A. Gruessner.1

    1Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY; 2Department of Surgery, SUNY Downstate Medical Center, Brooklyn, NY.

    Background: There is a significant increase in the number of older renal transplant recipients in the United States. Physical function (PF) may impact mortality in…
  • 2018 American Transplant Congress

    High Kidney Donor Profile Index (KDPI) Donor Kidneys: Use Them, Don't Lose Them!

    D. Harriman, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, M. Gautreaux, W. Doares, S. Kaczmorski, R. Stratta.

    Surgery, Medicine, Pathology, Pharmacy, Wake Forest Baptist Medical Center, Winston-Salem, NC.

    Introduction: With the development of the Kidney Donor Profile Index (KDPI) and a new Kidney Allocation System (KAS) implemented on 12/4/14, the expanded criteria donor…
  • 2018 American Transplant Congress

    Furosemide Stress Test as a Predicting Biomarker for Delayed Graft Function in Kidney Transplantation

    S. Udomkarnjananun,1 N. Townamchai,1 K. Iampenkhae,2 Y. Avihingsanon,1 S. Eiam-Ong,1 K. Praditpornsilpa.1

    1Nephrology, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand; 2Pathology, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.

    Delayed graft function (DGF) is considered as a risk factor for long-term allograft failure and rejection episodes.There is currently no biomarker in the immediate post-kidney…
  • 2018 American Transplant Congress

    Urinary Tract Infections May Be Associated with De Novo Donor-Specific Anti-Human Leucocyte Antigen Antibodies: Single-Center Study

    M. Everly,1 A. Babu,1 K. Briley,2 P. Bolin,2 S. Kendrick,3 H. Jones,3 K. McLawhorn,3 A. Maldonado,4 C. Haisch,2 D. Leeser,2 L. Rebellato.2

    1Terasaki Research Institute, Los Angeles; 2East Carolina University, Greenville, NC; 3Eastern Nephrology Associates, Greenville, NC; 4Vidant Medical Center, Greenville, NC.

    Introduction: We have recently shown that immunosuppression reduction with BK virus is associated with the development of de novo donor anti-human leukocyte antigen-specific antibodies (dnDSA).…
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