Am J Transplant, Volume 18, Suppl 3 Archives - Page 170 of 211 - ATC Abstracts

2018 American Transplant Congress
Outcomes of C4d+ Immunostaining in Heart Transplantation: Is All Immunologic AMR Bad?
M. Rafiei, J. Patel, E. Kransdorf, R. Levine, S. Dimbil, S. Mersola, G. Esmailian, D. Geft, D. Chang, L. Czer, J. Kobashigawa.
Cedars Sinai Medical Center, Los Angeles, CA.
Purpose: Antibody-mediated rejection (AMR) remains a threat to patients (pts) following heart transplant (HTx). C4d immunostaining is one component involved in the diagnosis of AMR…
2018 American Transplant Congress
Kidney Transplant Allocation with CMV Seromatching Reduces CMV Infection without Affecting Wait Times
A. Narra,¹ L. Strasfeld,² D. Basuli,¹ M. Stack,¹ E. Langewisch,³ A. Olyaei,¹ D. Norman,^1,4 J. Lockridge.^1,4
¹Transplant Nephrology, Oregon Health and Science University, Portland, OR; ²Infectious Diseases, OHSU, Portland, OR; ³Transplant Nephrology, University of Nebraska Medical Center, Omaha, NE; ⁴Transplant Nephrology, Portland VA, Portland, OR.
Cytomegalovirus (CMV) infection is a major cause of morbidity and mortality in kidney transplant recipients.A pre-transplant allocation strategy by matching deceased kidney donors and recipients…
2018 American Transplant Congress
One-Pump versus Two-Pump Normothermic Ex Vivo Perfusion Machines in Discarded Human Livers
A. Hassan, Q. Liu, D. Pezzati, A. Nassar, B. Soliman, M. Blum, P. Grady, G. Iuppa, T. Uso, J. Fung, K. Abu-Elmagd, C. Quintini.
Transplant Surgery, Cleveland Clinic, Cleveland.
Introduction:Physiologic flows and pressures need to be provided by the ex vivo liver perfusion device. We hypothesized that the 1-pump designed machines would provide the…
2018 American Transplant Congress
Deceased Donor Urinary Biomarker Signature and the Effectiveness of Peritransplant Lymphocyte Depletion on Early Renal Allograft Function
S. Bernd,² P. Heeger,¹ T-.P. Heather,³ I. Hall,⁷ M. Doshi,⁴ F. Weng,⁵ P. Reese,⁶ C. Parikh.³
¹Icahn School of Medicine Mount Sinai, New York, NY; ²University of Ulm, Ulm, Germany; ³Yale University School of Medicine, New Haven, CT; ⁴Wayne State University, Detroit, MI; ⁵Barnabas Health, Livingston, NJ; ⁶University of Pennsylvania, Philadelphia, PA; ⁷University of Utah School of Medicine, Salt Lake City, UT.
Purpose: Delayed graft function (DGF) is associated with increased allogaft immunogenicity and decreased long-term survival. We hypothesized that high levels of donor urinary biomarkers for…
2018 American Transplant Congress
Are Donation after Cardiac Death (DCD) Kidneys Unsuitable for Pediatric Recipients?
M. MacConmara,¹ S. Levea,² C. Hwang.¹
¹Surgery, UT Southwestern Medical Center, Dallas, TX; ²Medicine, UT Southwestern Medical Center, Dallas, TX.
Introduction: Despite the fact that the number of pediatric patients listed for kidney transplantation far exceeds the supply of deceased donor kidneys, there is a…
2018 American Transplant Congress
Private Insurance is Associated with Reduce Access to HCV Therapy after Liver Transplantation
D. Axelrod,¹ M. Schnitzler,² B. Kasiske,³ G. Hess,⁴ R. Bloom,⁵ F. Gordon,¹ H. Randall,² K. Lentine.²
¹Lahey Clinic, Burlington; ²Saint Louis U, St. Louis; ³SRTR, Minneapolis; ⁴Symphony Health, Conshohocken; ⁵U Penn, Philadelphia.
Effective treatment for hepatitis C virus (HCV) infection has revolutionized post liver transplant (LTx) care. Administration of direct-acting antiviral agents (DAAs) after HCV+ LTx results…
2018 American Transplant Congress
Kidney Allograft Vascular Disease Post-Transplant (KTX): Risk Factors and Implications
M. El Ters,¹ L. Cornell,² J. Grande,² F. Cosio.¹
¹Medicine, Mayo Clinic, Rochester, MN; ²Pathology, Mayo Clinic, Rochester, MN.
Background: Over time grafts develop arteriosclerosis (ART)and arteriolar hyalinosis (AH). Previous studies associated AH with calcineurin inhibitors (CNI), diabetes (DM), kidney age and hypertension. Other…
2018 American Transplant Congress
Genomic Diversity of Epstein Barr Virus in Post-Transplant Lymphoproliferative Disorder
E. Maloney,¹ V. Busque,² S. Hui,² S. Krams,^1,2 C. Esquivel,^1,2 O. Martinez.^1,2
¹Stanford Immunology, Stanford University School of Medicine, Stanford, CA; ²Department of Surgery/Division of Abdominal Transplantation, Stanford University School of Medicine, Stanford, CA.
Purpose: In transplant recipients, Epstein-Barr Virus (EBV) is associated with the development of B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD). We utilized next-generation sequencing…
2018 American Transplant Congress
Identification of T Cells as Target of Intervention to Decrease Anti-LG3 Autoantibody Levels Prior to Transplantation
M. Dieudé, L. Padet, A. Karakeussian-Rimbaud, B. Yang, J. Turgeon, H. Cardinal, M-.J. Hébert.
Research Centre, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal, QC, Canada.
Autoantibodies against perlecan/LG3 fragment (anti-LG3) have been associated with accelerated allograft rejection and long-term renal allograft dysfunction. Intriguingly, anti-LG3 are present prior to transplantation in…
2018 American Transplant Congress
A Novel Nomogram-Based Approach for Defining the Effect of Transplantation on Cancer Recurrence Risk
N. Ejaz,¹ R. Alloway,¹ F. Paterno,¹ A. Singhal,¹ X. Ji,² M. Kattan,² E. Woodle.¹
¹U of Cincinnati, Cincinnati; ²Cleveland Clinic, Cleveland.
The effect of transplantation on renal cell cancer (RCC) recurrence risk has not yet been precisely defined. Validated nomograms for predicting RCC recurrence risk (viz,…