Am J Transplant, Volume 18, Suppl 3 Archives - Page 158 of 211 - ATC Abstracts

2018 American Transplant Congress
Living Kidney Donation: Impact of Transplant Center Labor, Organization, and Resources
D. Moore,¹ M. Dietrich,¹ P. Buerhaus,² J. Rodrigue,³ A. Minnick.¹
¹Vanderbilt University, Nashville; ²Montana State University, Bozeman; ³Beth Israel Deaconess, Boston.
Purpose: Impact of transplant center program size, staffing, and organization on LKD outcomes is unknown. This study describes the labor inputs, organization, and resources available…
2018 American Transplant Congress
Financial Burden of Liver Transplant vs Resection for HCC
J. Butler, N. Skill, C. Kubal, D. O'Brien, J. Kays, J. Fridell, M. Maluccio.
Surgery, Indiana University, Indianapolis, IN.
There is considerable commentary regarding liver transplant vs resection for the treatment of hepatocellular carcinoma (HCC). While liver transplant provides longer survival when compared to…
2018 American Transplant Congress
Donor Derived Transmissions in 2016-2017: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)
C. Wolfe, S. Tlusty, G. Vece, R. Bag, G. Berry, J. Bucio, L. Danziger-Isakov, D. Florescu, D. Goldberg, C. Ho, R. La Hoz, K. Lilly, M. Malinis, A. Mehta, M. Nalesnik, R. Sawyer, L. Strasfeld, P. Wood, N. Theodoropoulos, M. Michaels.
DTAC, United Network for Organ Sharing, Richmond, VA.
The DTAC evaluates unanticipated potential donor-derived transmission events (PDDTE), including mostly infections (I) & malignancies (M), to assess for likelihood of donor transmission. Reporting policy…
2018 American Transplant Congress
Reducing No-Show Rate and Filling Cancelled Appointments: Multi-Faceted Interventions Markedly Reduced Time to Kidney Transplant Evaluation
E. Gibney, K. Payne, C. Fowler.
Piedmont Transplant Institute, Piedmont Atlanta Hospital, Atlanta, GA.
Introduction: Time from referral to appointment for kidney transplant evaluation is an important metric. Demands of dialysis schedules and transportation logistics typically lead to high…
2018 American Transplant Congress
The Results of the PRISM (Prediction of Rejection In Sensitized Patient Blood SaMples) Trial with a Novel Bioassay
F. Vincenti, A. Schroeder, S.-C. Hseish, J. Liberto, P. Towfighi, C. Koh, T. Sigdel, M. Sarwal.
Surgery and Medicine, University of California San Francisco, San Francisco.
Background. kSORT, a 17 gene blood biomarker, has been retrospectively validated for detection of BPAR and immune quiescence in kidney tx. This is the first…
2018 American Transplant Congress
The Likelihood of Re-Transplantation in Patients Undergoing Allograft Nephrectomy
G. Lucisano,¹ P. Brookes,² E. Santos-Nunez,² N. Firmin,² N. Gunby,² S. Hassan,¹ A. Gueret-Wardle,¹ M. Willicombe,¹ D. Taube.¹
¹Renal and Transplant Centre, Imperial College Healthcare NHS Trust, London, United Kingdom; ²Histocompatibility and Immunogenetics, Imperial College Healthcare NHS Trust, London, United Kingdom.
Introduction: transplant nephrectomy (NX) is a known cause of allosensitisation after graft failure. As yet, there is no consensus for the management of the patient…
2018 American Transplant Congress
Global Expression Profiles of miRNA and Expression Patterns and Localization of the miR-21 in One-Hour Biopsy Specimens of Human Kidney Tansplantation from Donors after Cardiac Death
M. Kusaka,¹ N. Fukami,¹ H. Sasaki,¹ A. Kawai,¹ T. Kenmochi,² T. Ito,² R. Shiroki,¹ K. Hoshinaga.¹
¹Urology, Fujita-Health University, Toyoake/Aichi, Japan; ²Transplant Surgery, Fujita-Health University, Toyoake/Aichi, Japan.
Because of the global shortage of renal grafts, kidney transplantation (KTx) from donors after cardiac death (DCDs) is an alternative way of obtaining KTx from…
2018 American Transplant Congress
Non-Invasive Imaging Modalities for Immune Monitoring of Vascularized Composite Allografts Using a Translational Large Animal Model
J. Etra,¹ K. Cilwa,² G. Furtmueller,¹ A. Leto Barone,¹ K. Kolegraff,¹ E. Elster,¹ W. Lee,¹ G. Brandacher.¹
¹Department of Plastic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; ²Naval Medical Research Center, Silver Springs, MD; ³Department of Surgery, Uniformed Services, University of Health Sciences and Walter Reed National Military Medical Center, Bethesda, MD.
PurposeImmunological complications and skin rejection remains an obstacle in broadening the applicability of vascularized composite allotransplantation (VCA). Currently, diagnosis of rejection relies on skin biopsies…
2018 American Transplant Congress
False-Positive Flow-Cytometric T Cell Crossmatch Associated with Blood Type Antigen Expressed on Lymphocytes in ABO Incompatible Kidney Transplantation
D. Iwami,¹ M. Ito,² K. Hotta,¹ H. Higuchi,¹ N. Shinohara.¹
¹Renal and Genitourinary Surgery, Hokkaido University, Graduate School of Medicine, Sapporo, Japan; ²Division of Laboratory and Transfusion Medicine, Hokkaido University Hospital, Sapporo, Japan.
Background: Flow-cytometric T cell crossmatch (FTXM) uses live donor lymphocytes to detect anti-donor-human leukocyte antigen (HLA) IgG antibodies. Therefore, the results can be affected by…
2018 American Transplant Congress
In Vivo and In Vitro PPAR-y Activation Decreases M1-Macrophage Polarization and Improves Liver Ischemia Reperfusion Injury
I. Linares,¹ A. Bartczak,¹ K. Farrokhi,¹ D. Kollmann,¹ M. Kaths,¹ M. Hamar,¹ P. Urbanellis,¹ S. Ganesh,¹ O. Adeyi,² P. Yip,³ M. Selzner,¹ N. Selzner.¹
¹Multi Organ Transplant Program, Toronto General Hospital, Toronto, ON, Canada; ²Department of Pathology, Toronto General Hospital, Toronto, ON, Canada; ³Laboratory of Medicine and Pathobiology, Toronto General Hospital, Toronto, ON, Canada.
Background:M1-Macrophage polarization has been studied as a potential target to decrease inflammatory response in sepsis and inflammation-related diseases. Its role in the setting of inflammatory…