Am J Transplant, Volume 18, Suppl 3 Archives - Page 158 of 211 - ATC Abstracts

2018 American Transplant Congress
Benefit of Anti-Hepatitis B Immunoglobulin(HBIG) Monotherapy Compared to HBIG Combined with Entecavir in Long Term Renal Function
J. Lee,¹ D. Kim,¹ J. Lee,² S. Kim,³ H. Lee,⁴ S. Song,⁵ J. Lee,¹ M. Ju,¹ G. Choi,¹ D. Joo,¹ J. Choi,¹ S. Kim,¹ Y. Jung.¹
¹Department of Surgery, Yonsei University of College of Medicine, Seoul, Republic of Korea; ²Department of Surgery, CHA Bundang Medical Center, Seongnam, Republic of Korea; ³Department of Surgery, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea; ⁴Department of Surgery, Ilsan Hospital, Ilsan, Republic of Korea; ⁵Department of Surgery, Ehwa Wonmen Hospital, Seoul, Republic of Korea.
Background: To reduce the HBV reinfection after liver transplantation, anti-hepatitis B immunoglobulin (HBIG) alone or combination with antiviral nucleotide analogues are usually used regimen. However,…
2018 American Transplant Congress
Upper Limb Early Cannulation Arteriovenous Grafts (ecAVG) for Complex Vascular Access – A Healthy Alternative to Central Venous Catheters (CVC)
M. Khurram,¹ I. Mosca,² F. Calder.³
¹Department of Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom; ²Department of Transplantation, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom; ³Department of Transplantation, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
IntroductionPatients with few transplant options and failing dialysis access are challenging to manage. Transitioning away from a CVC to fistula / graft is often difficult.…
2018 American Transplant Congress
A Single Center Outcomes Analysis of UNOS Defined "Hard to Place Kidneys"
Y. Qazi, K. Lee, A. Jones, L. Aguirre, M. Parma, M. Smogorzewski, T. T. Maw, L. Sher.
Keck Medical Center at USC, Los Angeles, CA.
The discard rate of potentially usable kidneys remains dismal despite a critical shortage of organs. The Scientific Registry of Transplant Recipients (SRTR) now provides a…
2018 American Transplant Congress
Laparoscopic Donor Nephrectomy – The BMI Effect
V. Chia,¹ F. Khan,² M. Newell,² L. J. Chen.³
¹Surgery, Southmead Hospital, Bristol, England, United Kingdom; ²Clinical Science Institute, National University of Ireland, Galway, Ireland; ³Miami Transplant Institute, University of Miami, Miami.
Aims: To evaluate the outcomes of Laparoscopic Donor Nephrectomy (LDN) across 4 BMI groups.Methods : Using the SRTR database, all LDNs performed between 2006-2015 were…
2018 American Transplant Congress
Origin and Traffic of Donor-Derived Extracellular Vesicles during Allo-Sensitization
F. Zeng,¹ W. Shufesky,¹ M. Yang,¹ Q. Liu,¹ A. Larregina,² A. Morelli.¹
¹T.E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; ²Department of Dermatology, University of Pittsburgh, Pittsburgh, PA.
The idea that donor dendritic cells (DCs) transplanted with the grafts and mobilized to draining lymphoid tissues (dLTs) present donor MHC molecules to allo-reactive naïve…
2018 American Transplant Congress
Donor-Derived Cell-Free DNA Identifies Antibody-Mediated Rejection with Graft Injury in DSA-Positive Kidney Transplant Recipients
S. Jordan,¹ S. Bunnapradist,² J. Bromberg,³ A. Langone,⁴ D. Hiller,⁵ J. Yee,⁵ J. Sninsky,⁵ R. Woodward,⁵ A. Matas.⁶
¹Cedars-Sinai Medical Center, Los Angeles, CA; ²UCLA, Los Angeles, CA; ³University of Maryland School of Medicine, Baltimore, MD; ⁴Vanerbilt University Medical Center, Nashville, TN; ⁵CareDx, Brisbane, CA; ⁶University of Minnesota School of Medicine, Minneapolis, MN.
Purpose: Donor-derived cell-free DNA (dd-cfDNA) discriminates active rejection in kidney transplant patients. Donor-specific antibodies (DSA) to HLA antigens are associated with risk of antibody-mediated rejection…
2018 American Transplant Congress
Introduction of Direct Acting Antivirals for HCV: Fewer Kidney Discards but a Long Way to Go
T. Alhamad,¹ R. Thakkar,¹ D. Brennan,² J. Lappin,³ B. Kaplan,³ A. Malone,¹ V. Hicks,¹ J. Wellen,¹ K. Lentine.⁴
¹Washington University in St. Louis, St. Louis; ²Johns Hopkins University, Baltimore; ³Baylor Scott and White, Temple; ⁴Saint Louis University, St. Louis.
Organ shortage remains a great challenge facing the field of kidney transplantation. Donor hepatitis C virus positivity (DHCV+) is one of the highest ranking factors…
2018 American Transplant Congress
Epitope/Eplet Mismatch in Pediatric Renal Transplantation and Development of Donor Specific Antibody
R. George,¹ H. Sullivan,² R. Garro,¹ P. Winterberg,¹ B. Warshaw,¹ H. Gebel,² R. Bray.²
¹Pediatric Nephrology, Emory University & Children's Healthcare of Atlanta, Atlanta, GA; ²Dept. of Pathology, Emory Transplant Center, Emory University, Atlanta, GA.
Background: De-novo donor specific antibody (DSA) is one of the strongest independent predictors of graft loss with HLA mismatching being a major risk factor for…
2018 American Transplant Congress
Complex Combined Thoracic/liver Transplant: A Seven Year Experience
N. Presser, J. DiNorcia, V. Agopian, H. Yersiz, D. Farmer, R. Busuttil, F. Kaldas.
Liver and Pancreas Transplant, UCLA, Los Angeles, CA.
Background: While rare, combined Thoracic/Liver transplants are employed with increasing frequency. Consistent data regarding the technical conduct, patient selection and outcomes in this highly complex…
2018 American Transplant Congress
The Role of CD46 in Early Islet Engraftment in a Dual Transplant Model
Q. Gao, K. Samy, R. Davis, M. Song, A. MacDonald, F. Leopardi, T. How, K. Williams, G. Devi, B. Collins, A. Kirk.
Department of Surgery, Duke University School of Medicine, Durham, NC.
IntroductionMembrane cofactor protein (CD46) is known to attenuate the complement cascade by facilitating cleavage of C3b and C4b. In solid organ xenotransplantation, organs expressing CD46…