ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Leukocytes from Recipients with Severe Primary Graft Dysfunction after Lung Transplant Adoptively Transfer Alloreactivity to Vessel Grafts Trans Vivo

    A-.K. Knoefel,1 T. Siemeni,1 N. Madrahimov,1 W. Sommer,1 M. Avsar,1 L. Ahrens,1 I. Tudorache,1 A. Haverich,1 C. Falk,2 G. Warnecke.1

    1HTTG, MHH, Hannover, Germany; 2Transplantimmunology, MHH, Hannover, Germany.

    Introduction: Primary graft dysfunction (PGD) is the main cause of early mortality after lung transplantation (LTx). Multiple mechanisms have been described, but the link between…
  • 2018 American Transplant Congress

    Hyperglycemia-Triggered S1P/SIPR3signaling Exacerbates Liver Ischemia/Reperfusion Injury by Regulating M1/M2 Polarization

    J. Rao,1,2 Y. Hu,1 C. Yang,1 S. Yang,1 F. Cheng,1 F. Zhang,1 X. Wang,1 Y. Zhai,1,2 L. Lu.1,2

    1Department of Liver Surgery/Liver Transplantation Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; 2Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles.

    Background and Aims: Hyperglycemia/Diabetes is an adverse risk factor for hepatic ischemia/reperfusion injury (IRI) during liver transplantation or hepatectomy; however, the underlying mechanism remains unclear.Sphingosine…
  • 2018 American Transplant Congress

    Urinary C-X-C Motif Chemokines 13 is a Noninvasive Biomarker of Antibody-Mediated Renal Allograft Rejection

    D. Chen, J. Chen.

    Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.

    Background: Since acute rejection remains one of the major complications which necessitate periodic surveillance, noninvasive diagnostic/prognostic methods are preferred by renal transplant recipients. Here we…
  • 2018 American Transplant Congress

    Waning Enthusiasm for a Once Promising Test: C1q Testing Does Not Provide Prognostic Information for DSA Screening Protocols

    A. Gilbert, D. Li, M. Awwad, S. Rosen-Bronson, P. Abrams, J. Verbesey, G. Vranic, M. Cooper.

    Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.

    Introduction: Testing of donor specific antibodies (DSA) for binding of complement component C1q has been used to better elucidate pathologic antibodies from more benign reactions.…
  • 2018 American Transplant Congress

    ABO-Incompatibility Lower Incidence of DSA-Induced Antibody-Mediated Rejection

    D. Lee,1 B. Kim,1 J. KIm,1 I. KIm,1 M. Jeon.1

    1Nephrology, Medicine, Maryknoll General Hospital, Busan, Republic of Korea; 2Laboratory Medicine, Maryknoll General Hospital, Busan, Republic of Korea; 3Surgery, Maryknoll General Hospital, Busan, Republic of Korea; 4Urology, Maryknoll General Hospital, Busan, Republic of Korea; 5Pathology, Maryknoll General Hospital, Busan, Republic of Korea.

    Introduction:Donor-specific anti-HLA antibody (DSA) and Anti-ABO antibody are major barriers for successful kidney transplantation. Limited data are available about the existences of both DSA and…
  • 2018 American Transplant Congress

    Delayed Graft Function in Live Donor HLA-Incompatible Kidney Transplant Recipients: A Multicenter Study

    J. Motter,1 A. Massie,1 J. Garonzik Wang,1 K. Jackson,1 X. Luo,1 A. Muzaale,1 B. Orandi,2 D. Segev.1

    1JHU, Baltimore; 2UCSF, San Francisco.

    Background: Many patients with a willing, but incompatible live donor choose to undergo incompatible live donor kidney transplantation (ILDKT) facilitated by desensitization procedures to eliminate…
  • 2018 American Transplant Congress

    Gains from Joining Kidney Paired Donation with Several Incompatible Donors

    M. Bray, W. Wang, P. Song, J. Kalbfleisch.

    University of Michigan, Ann Arbor, MI.

    In kidney paired donation (KPD), a transplant candidate with an incompatible donor joins a pool of similar pairs in an effort to find new transplant…
  • 2018 American Transplant Congress

    Brincidofovir for Disseminated Adenovirus in Kidney and Kidney-Pancreas Transplant Recipients: Report of a Case Series

    L. Bowman, R. Baliga, C. Mayer.

    Tampa General Hospital, Tampa, FL; Florida Kidney Physicians, Tampa, FL; Infectious Disease Associates of Tampa Bay, Tampa, FL.

    Background: Adenoviruses (AdV) are DNA viruses that can cause significant morbidity and mortality rates up to 50% with disseminated disease. The incidence post-renal transplantation is…
  • 2018 American Transplant Congress

    Lower Uric Acid Level after Kidney Transplantation Impact on Better Long-Term Allograft Outcomes

    D. Kim,1 H. Choi,2 Y. Jung,1 J. Lee,1 J. Lee,1 J. Lee,1 K. Huh,1 M. Kim,1 B. Kim,2 Y. Kim.1

    1Transplantation Surgery, Yonsei University Health System, Seoul, Korea; 2Nephrology, Yonsei University Health System, Seoul, Korea.

    BackgroundIt has been on debate that hyperuricemia was an independent risk factor for poor prognosis in kidney transplantation. Considering the link of UA with diabetes,…
  • 2018 American Transplant Congress

    Kidney Transplantation is Associated with Decreasing Native T1 Time: A Cardiac Magnetic Resonance Study

    M. Contti,1 L. de Andrade,1 H. Nga,1 M. Valiatti,1 H. Takase,1 A. Bravin,1 A. Mauricio,2 M. Barbosa.3

    1Internal Medicine, Botucatu Medical School, Botucatu, Sao Paulo, Brazil; 2Radiology, Heart Institute of the Clinics Hospital at the Faculty of Medicine, University of São Paulo, São Paulo, Brazil; 3Radiology, Centro Avançado de Radiologia e Diagnóstico por Imagem, Presidente Prudente, Sao Paulo, Brazil.

    Patients with stage 5 chronic kidney disease (CKD) have high rate of cardiovascular death. Kidney transplantantion, on the other hand, is associated with lower cardiovascular…
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