ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Validation Study of Gene Expression Signatures Associated with Antibody-Mediated Rejection (ABMR) and Cell-Mediated Rejection (CMR) in Renal Allograft Biopsies (Bx) Suggests Complexity of Molecular Diagnosis for ABMR Compared to CMR

    H. Zhang,1 C. Nast,2 J. Doldron,2 M. Cheung,2 A. Vo,3 S. Jordan,3 M. Toyoda.1

    1Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; 2Pathology, Cedars-Sinai Medical Center, Los Angeles, CA; 3Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA.

    Background: Various molecular signatures specific to ABMR and CMR based on gene expression in renal allograft Bx or peripheral blood mononuclear cells (PBMC) of renal…
  • 2018 American Transplant Congress

    Clinical Significance of Microvascular Inflammation in the Absence of Anti-HLA DSA in Kidney Transplantation

    S. Parajuli, R. Redfield, F. Aziz, N. Garg, M. Mohamed, W. Zhong, T. Ellis, A. Djamali, D. Mandelbrot.

    University of Wisconsin, Madison.

    Background: It is not uncommon to have biopsy specimens meeting Banff glomerulitis (g) plus peritubular capillaritis (ptc) and/or c4d scores that meet criteria for antibody…
  • 2018 American Transplant Congress

    Impact of Pretransplant Donor-Specific Antibodies on Kidney Allograft Recipients with Negative Flow Cytometry Crossmatches

    H. Kwon, Y. Kim, J. Choi, S. Shin, J. Jung, M. Cho, J. Kim, D. Han.

    Asan Medical Center, Seoul, Korea.

    This study evaluated the impact of DSA on clinical outcomes in KT recipients negative on FCXM. Of 575 consecutive patients who underwent living donor KT…
  • 2018 American Transplant Congress

    A Substantial Fraction of Surveillance Transplant Biopsies Have Clinically Actionable Findings

    A. Shammout,1 A. Naik,2 M. Samaniego,2 E. Farkash.1

    1Pathology, Michigan Medicine, Ann Arbor; 2Nephrology, Michigan Medicine, Ann Arbor.

    Background: Surveillance biopsies in renal transplant recipients may detect subclinical disease that affects graft longevity. At our transplant center, most patients with stable allograft function…
  • 2018 American Transplant Congress

    Interactive Software for Simulation and Management of a Kidney Paired Donation Program

    M. Bray,1 W. Wang,1 M. Rees,2 P. Song,1 A. Leichtman,3 V. Ashby,1 J. Kalbfleisch.1

    1University of Michigan, Ann Arbor, MI; 2Alliance for Paired Donation, Maumee, OH; 3Arbor Research, Ann Arbor, MI.

    In kidney paired donation (KPD), candidates with willing but incompatible donors are pooled together with the goal of finding new transplant opportunities by exchanging donors.…
  • 2018 American Transplant Congress

    Cause of ESRD is Not Associated with Risk of Post-Transplant CMV Infection

    S. Panzer, S. Peery, B. Astor, A. Djamali, T. Singh.

    University of Wisconsin Madison, Madison, WI.

    Purpose: Cytomegalovirus (CMV) infection is commonly encountered following kidney transplantation and is associated with patient morbidity and mortality. While preventative pharmacotherapy is used to prevent…
  • 2018 American Transplant Congress

    Outcomes of Kidney Transplantation from HBsAg Positive Donors to HBsAb Positive Recipients

    G. Chen, C. Wang, Z. Wu, X. Liu, C. Wang, L. Chen.

    Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

    Objective To investigate the outcomes of transplanting kidneys from HBsAg positive donors to HBsAb positive recipients.Methods We retrospectively collected data of 57 kidney transplants from…
  • 2018 American Transplant Congress

    Impact of Postoperative Serum Chloride Changes on Graft Function and Acute Rejection in Recipients of Living Kidney Transplants

    V. Vakil, D. Keys, M. Junghare, S. Jackson, D. Berglund, A. Matas, S. Riad.

    U of MN, Minneapolis.

    Background: In the non-transplant setting, hyperchloremia has been associated with kidney injury. We sought to study the impact of serum chloride (SCl) on transplant outcomes.Methods:…
  • 2018 American Transplant Congress

    Measures of Physical Frailty, Cardiac Function and Cardiac Biomarkers among Kidney Transplant Candidates

    S. Gilligan,1 S. Anand,2 D. Morris,2 M. Minder,1 T. Srinivas.2

    1Intermountain Medical Center, Murray, UT; 2University of Utah, Salt Lake City, UT.

    Background: Elevated troponin T at transplant evaluation has been reported to confer risk of cardiovascular mortality among renal transplants. We use troponin T along with…
  • 2018 American Transplant Congress

    Portal Vein Thrombosis (PVT) in Liver Transplantation – Recent Experience

    D. Bruce, H. Bohorquez, J. Seal, A. Cohen, E. Bugeaud, I. Carmody, D. Sonnier, A. Mathur, L. De Gregorio, H. Sharma, G. Loss.

    Ochsner Multi-Organ Transplant Institute, Ochsner Medical Center, New Orleans, LA.

    From 01-Nov-2012 to 31-Oct-2017, 1025 liver transplants were done at our center. Excluding retransplants and combined liver-kidney transplants, 830 transplants were studied for this abstract…
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