ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Defining Response to Standard of Care Treatment in Kidney Recipients with Antibody-Mediated Rejection: Role of C1q-Binding Donor-Specific Anti-HLA Antibodies

    Y. Bouatou, D. Viglietti, O. Aubert, A. Loupy, C. Lefaucheur.

    Paris Translational Research Center for Organ Transplantation, Paris, France.

    A major hurdle to improving clinical care in kidney transplantation is the lack of biomarkers of the response to antibody-mediated rejection (ABMR) treatment. We investigated…
  • 2018 American Transplant Congress

    Comparison of Microvascular Inflammation in Renal Allograft Tissue between ABO Incompatible and ABO Compatible Kidney Transplantation

    E. Ko,1,2 B. Choi,1,2 C. Park,1,2 Y. Kim,1,2 C. Yang,1,2 B. Chung.1,2

    1Transplant Research Center, College of Medicine, Seoul St.Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea; 2Division of Nephrology, Department of Internal Medicine, College of Medicine, Seoul St.Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.

    Background: Microvascular inflammation (MVI) is considered as a pathological marker for antibody-mediated rejection (AMR) in the presence of donor-specific antibody (DSA). We aimed to investigate…
  • 2018 American Transplant Congress

    Interstitial Inflammation is Correlated with DQ Antibodies in Kidney Transplant Recipients

    C. Harris, L. Anderson, R. Khaim, J. Choudhuri, R. Shapiro, S. Florman, F. Salem, M. Menon.

    Icahn School of Medicine at Mount Sinai, New York.

    Background: Studies have shown that borderline rejection (BR) and acute cellular rejection (ACR) often co-occur with antibody-mediated rejection (AMR). We examined the association between interstitial…
  • 2018 American Transplant Congress

    Decreased Clinical Significance of Isoagglutinin Titer with the Current Desensitization Protocol in ABO-Incompatible Kidney Transplantation

    C. Baek, H. Kim, W. Yang, D. Han, S-.K. Park.

    Department of Internal Medicine, Division of Nephrology, Asan Medical Center, Seoul, Republic of Korea; Department of Surgery, Asan Medical Center, Seoul, Republic of Korea.

    ABO-incompatible (ABOi) kidney transplantation (KT) has become a routine procedure with graft survival rates comparable to those of ABO-compatible KT. However, the clinical significance of…
  • 2018 American Transplant Congress

    Evaluation of KPD: Does It Improve Overall Transplant Center Performance?

    M. Rees,3 E. Michelin,1 N. Koizumi,2 J. Ortiz.3

    1West Virginia School of Osteopathic Medicine, Lewisburg, WV; 2George Mason University, Fairfax, VA; 3University of Toledo College of Medicine, Toledo, OH.

    Introduction: The medical community is facing a constant shortage of kidneys for transplant patients. The most effective way to combat the deficit is to increase…
  • 2018 American Transplant Congress

    Relation between Seroprevalence of Cytomegalovirus and Graft Survival in Japanese Kidney Transplant Recipients: The Japan Academic Consortium of Kidney Transplantation Study

    K. Miyake,1,2 M. Okumi,1 K. Unagami,3 Y. Kakuta,1 H. Shirakawa,4 K. Omoto,5 H. Ishida,1 K. Tanabe.1

    1Urology, Tokyo Women's Medical University, Tokyo, Japan; 2Kidney Transplantation, Shonan Kamakura General Hospital, Kamakura, Japan; 3Nephrology, Tokyo Women's Medical University, Tokyo, Japan; 4Urology, Okubo Hospital, Tokyo, Japan; 5Urology, Toda Chuo General Hospital, Saitama, Japan.

    BackgroundCytomegalovirus (CMV) infection is one of major causes of morbidity in kidney transplant recipients (KTRs). However, the current prevalence of CMV in KTRs and the…
  • 2018 American Transplant Congress

    Clinical Validation of a Novel ELISpot-Based In Vitro Diagnostic Assay to Monitor CMV-Specific Cell-Mediated Immunity in Kidney Transplant Recipients

    B. Banas,1 D. Steubl,2 L. Renders,2 D. Chittka,1 M. Banas,1 T. Wekerle,3 M. Koch,4 O. Witzke,5 A. Muehlfeld,6 C. Sommerer,7 A. Habicht,8 C. Hugo,9 T. Huenig,10 M. Lindemann,5 T. Schmidt,11 A. Rascle,11 S. Barabas,11 L. Deml,11 R. Wagner,1,11 B. Kraemer,12 B. Krueger.12

    1University Clinic, Regensburg, Germany; 2Clinic rechts der Isar TUM, Munich, Germany; 3Medical University, Vienna, Austria; 4University Clinic, Hamburg-Eppendorf, Germany; 5University Hospital, Essen, Germany; 6Uniklinik RWTH, Aachen, Germany; 7University Hospital, Heidelberg, Germany; 8LMU Medical Center, Munich, Germany; 9University Hospital, Dresden, Germany; 10University Hospital, Wuerzburg, Germany; 11Lophius Biosciences, Regensburg, Germany; 12UMM Uni. Heidelberg, Mannheim, Germany.

    Impaired cytomegalovirus (CMV)-specific cell-mediated immunity (CMV-CMI) is a major cause ofCMV reactivation and associated complications in solid-organ transplantation. Reliably assessing CMV-CMI is desirable to individually…
  • 2018 American Transplant Congress

    Evaluation of Salt Intake by 24-h Urinary Sodium Excretion in Kidney Transplant Patients

    T. Abe,1 M. Kawamura,1 S. Nakazawa,1 T. Kato,1 R. Imamura,1 N. Ichimaru,2 S. Takahara,2 N. Nonomura.1

    1Departments of Urology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan; 2Departments of Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

    Background: Dietary recommendations for chronic kidney disease advise 3 to 6 g/day of dietary salt intake. We evaluated current adherence to dietary recommendations for CKD…
  • 2018 American Transplant Congress

    Malignancy Complications after Kidney Transplantation, the Role of Immunosuppression

    M. Molina,1 J. Cabrera,2 E. Gonzalez,1 A. Hernández,1 N. Polanco,1 A. Andres.1

    1Nephrology Department, Hospital Universitario 12 de Octubre, Madrid, Spain; 2Nephrology Department, Hospital Evangelico, Montevideo, Uruguay.

    Introduction: Immunosuppression therapy is essential to avoid rejection after kidney transplantation. The chronic use of this drugs increases the risk of malignancy compared to general…
  • 2018 American Transplant Congress

    The Initial Hepatic Artery Reperfusion versus Initial Portal Reperfusion in Liver Transplantation: Where Do We Stand?

    R. Shahbazov,1 F. Azari,3 J. Alejo,2 M. Talanian,2 M. Fox,2 K. Kennedy,2 S. Kessel,2 A. Nickkholgh,1 D. Maluf,1 S. Pelletier.1

    1Surgery, University of Virginia Health System, Charlottesville, VA; 2School of Medicine, University of Virginia Health System, Charlottesville, VA; 3Surgery, University of Pennsylvania Medical Center, Philadelphia, PA.

    Introduction: While initial portal vein reperfusion (PVRP) of a liver allograft is nearly standardized, limited data suggests initial hepatic arterial reperfusion (HARP) may improve hemodynamics…
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