Am J Transplant, Volume 18, Suppl 3 Archives - Page 148 of 211 - ATC Abstracts

2018 American Transplant Congress
Long Term Renal and Patient Risks for Living Kidney Donors
Y. Kim, M. Yu, Y. Kim, H. Lee.
Division of Nephrology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.
Purpose:Recent studies have issued that living kidney donor (LKD) might be exposed to higher risk for end-stage renal disease (ESRD) and death, compared with healthy…
2018 American Transplant Congress
Novel Vascular Inflow Offers Renal Transplantation to Recipients with Severe Central and Peripheral Vascular Disease
S. Mao,¹ E. Giorgakis,² A. Moss,² T. Taner.¹
¹William J. von Liebig Center for Transplantation, Mayo Clinic, Rochester, MN; ²Transplantation Surgery, Mayo Clinic, Phoenix, AZ.
Background: Absence of suitable implant locations for donor renal vessels may be a major problem in patients with significant central and peripheral vascular disease. We…
2018 American Transplant Congress
The Stunning Rise in Organ Donors Deceased from Drug Overdose
N. Agrawal,¹ S. Rhazouani,¹ D. Reino,¹ D. McMichael,² C. McClenney,³ D. Sears,¹ K. Al Khalloufi,¹ S. Gebreselassie,¹ S. Ebaid,¹ M. Berho,⁴ X. Zervos,¹ C. Sheffield,¹ A. Tzakis.¹
¹Transplantation, Cleveland Clinic Florida, Weston, FL; ²Research, Cleveland Clinic, Cleveland, OH; ³Life Alliance Organ Recovery Agency, University of Miami, Miami, FL; ⁴Department of Pathology, Cleveland Clinic Florida, Weston, FL.
In the recent years we noticed an increase in the number of local deceased organ donors who had died of drug overdose. This coincides with…
2018 American Transplant Congress
Digital-Enabled Refills and Medication Adherence among Transplant Recipients
S. Boghani, H. Kirkham, G. Pietradoni, N. Hira.
Walgreen Co., Deerfield, IL.
Purpose: Impact of nonadherence among transplant recipients has been well documented as a significant contributor of allograft failure. The objective of this study was to…
2018 American Transplant Congress
Enhancement of Intrinsic Apoptosis via Bcl-2 Inhibition Promotes Induction of Robust Mixed Chimerism and Renal Allograft Tolerance without Myelosuppression in Nonhuman Primates
T. Oura,¹ A. Dehnadi,¹ I. Rosales,¹ H. Sasaki,¹ P. Cippa,² R. Fehr,² A. Cosimi,¹ T. Kawai.¹
¹Surgery, Center for Transplantation Science, Massachusetts General Hospital, Boston, MA; ²Medicine, University of Zurich, Zurich, Switzerland.
Background: Successful induction of mixed chimerism (MC) and renal allograft tolerance has been achieved in both nonhuman primate (NHP) and man following conditioning that included…
2018 American Transplant Congress
CD40 Signaling in Proximal Tubules Regulates Fibrosis in Both Hypertension and Chronic Allograft Rejection
V. Bletsos, J. Breidenbach, S. Haller, S. Stepkowski.
University of Toledo College of Medicine and Life Sciences, Toledo, OH.
Background: We explored the role of CD40 signaling in kidney proximal tubule epithelial cells on renal interstitial fibrosis (IF) in two models: hypertension; and chronic…
2018 American Transplant Congress
Optimizing Outcomes with a Collaborative Approach after Kidney Transplant in Hepatitis C-Positive Recipients Receiving Hepatitis C-Positive Grafts
A. Ray, R. Rubin, T. Ommert, R. Cross, C. Klein.
Piedmont Transplant Institute, Piedmont Healthcare, Atlanta, GA.
PURPOSE: To evaluate the multidisciplinary approach to HCV treatment in HCV+ kidney recipients receiving HCV+ grafts. METHODS: Single center review of treatment and outcomes in…
2018 American Transplant Congress
The First 9 Years of KPD through the National Kidney Registry: Characteristics of Donors and Recipients Compared to National Transplant Registries
S. Flechner,¹ A. Thomas,² M. Ronin,³ J. Veale,⁴ D. Leeser,⁵ S. Kapur,⁶ J. Piepert,⁴ D. Segev,² G. Hil,³ A. Waterman.⁴
¹Cleveland Clinic, Cleveland, OH; ²Johns Hopkins, Baltimore, MD; ³National Kidney Registry, Babylon, NY; ⁴UCLA, Los Angeles, CA; ⁵East Carolina, Greenville, NC; ⁶Cornell, New York, NY.
Purpose: The NKR is a voluntary network of 75 transplant centers in 28 States in the USA focused on the facilitation of live donor kidney…
2018 American Transplant Congress
Intragraft Gene Expression Differentiates Polyomavirus Nephropathy from T-Cell Mediated Rejection
B. Adam,¹ S. Wagner,¹ J. Bräsen,² V. Bröcker,² V. D'Agati,³ C. Drachenberg,⁴ E. Farkash,⁵ A. Farris,⁶ L. Geldenhuys,⁷ A. Magil,⁸ V. Nickeleit,⁹ P. Randhawa,¹⁰ H. Regele,¹¹ M. Mengel.¹
¹University of Alberta, Edmonton, Canada; ²Hannover Medical School, Hannover, Germany; ³Columbia University, New York; ⁴University of Maryland, College Park; ⁵University of Michigan, Ann Arbor; ⁶Emory University, Atlanta; ⁷Dalhousie University, Halifax, Canada; ⁸University of British Columbia, Vancouver, Canada; ⁹University of North Carolina, Chapel Hill; ¹⁰University of Pittsburgh, Pittsburgh; ¹¹Medical University of Vienna, Vienna, Austria.
Background: Improved immunosuppression protocols have reduced the incidence of T-cell mediated rejection (TCMR) but still carry a significant risk of BK polyomavirus nephropathy (BKVN). Despite…
2018 American Transplant Congress
Significant Alteration in Transplant Center Performance Assessment with Extended Patient Follow Up Time
J. Schold, D. Goldfarb, S. Flechner, A. Wee, E. Poggio.
Cleveland Clinic, Cleveland.
IntroductionCurrent transplant center performance models focus on 1-year graft and patient survival as primary outcomes. This is despite that 2.5 year cohorts are used to…