Am J Transplant, Volume 18, Suppl 3 Archives - Page 14 of 211 - ATC Abstracts

2018 American Transplant Congress
Increased Expression of CEACAM1 is Cytoprotective during Ischemia-Reperfusion Injury in Human Orthotopic Liver Transplantation
R. Sosa,¹ J. Nevarez-Mejia,¹ M. Rossetti,¹ A. Zarrinpar,² F. Kaldas,² C. Lassman,¹ B. Naini,¹ N. Datta,² R. Busuttil,² D. Gjertson,¹ J. Kupiec-Weglinski,² E. Reed.¹
¹Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA; ²Surgery, University of California, Los Angeles, Los Angeles, CA.
Background T cell exhaustion has recently been proposed as an alternative mechanism to prevent memory development and tissue damage arising during ischemia-reperfusion injury (IRI) in…
2018 American Transplant Congress
Does Pre-Operative Angiographic Kidney Embolization Decrease Complications in Allograft Nephrectomy?
D. Harriman, V. Mujumdar, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, R. Stratta.
Surgery, Medicine, Wake Forest Baptist Health, Winston-Salem, NC.
Introduction: Morbidity associated with allograft nephrectomy (AN) for treatment of failed or diseased kidney transplants is well documented. Pre-operative angiographic kidney embolization (PAKE), which induces…
2018 American Transplant Congress
Urinary Microbiome Associated with Chronic Allograft Dysfunction in Kidney Transplants
A. Israni,^1,2 A. Muthusamy,² B. Wu,³ B. Guo,³ D. Knights,⁴ G. Al-Ghalith,⁴ J. Wu,¹ W. Oetting,⁵ D. Schladt,² R. Remmel,⁵ P. Jacobson,⁵ For DeKAF Genomics & GEN03 Investigators.¹
¹Medicine, Hennepin County Medical Center, University of Minnesota (UMN), Minneapolis; ²Minneapolis Medical Research Foundation, Mpls; ³Biostatistics, UMN, Mpls; ⁴Computer Science, UMN, Mpls; ⁵College of Pharmacy, UMN, Mpls.
Background: Microbiome dysbiosis can lead to poor outcomes after kidney transplant (tx) presumably due to immune dysregulation elicited by the microbiome. We hypothesize that chronic…
2018 American Transplant Congress
Association of Physical Function and Survival in Elderly Renal Transplant Recipients
A. Brar,¹ F. Tedla,¹ M. Salifu,¹ R. Gruessner,² D. John,² N. Sumrani,² A. Gruessner.¹
¹Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY; ²Department of Surgery, SUNY Downstate Medical Center, Brooklyn, NY.
Background: There is a significant increase in the number of older renal transplant recipients in the United States. Physical function (PF) may impact mortality in…
2018 American Transplant Congress
High Kidney Donor Profile Index (KDPI) Donor Kidneys: Use Them, Don't Lose Them!
D. Harriman, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, M. Gautreaux, W. Doares, S. Kaczmorski, R. Stratta.
Surgery, Medicine, Pathology, Pharmacy, Wake Forest Baptist Medical Center, Winston-Salem, NC.
Introduction: With the development of the Kidney Donor Profile Index (KDPI) and a new Kidney Allocation System (KAS) implemented on 12/4/14, the expanded criteria donor…
2018 American Transplant Congress
Furosemide Stress Test as a Predicting Biomarker for Delayed Graft Function in Kidney Transplantation
S. Udomkarnjananun,¹ N. Townamchai,¹ K. Iampenkhae,² Y. Avihingsanon,¹ S. Eiam-Ong,¹ K. Praditpornsilpa.¹
¹Nephrology, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand; ²Pathology, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
Delayed graft function (DGF) is considered as a risk factor for long-term allograft failure and rejection episodes.There is currently no biomarker in the immediate post-kidney…
2018 American Transplant Congress
Urinary Tract Infections May Be Associated with De Novo Donor-Specific Anti-Human Leucocyte Antigen Antibodies: Single-Center Study
M. Everly,¹ A. Babu,¹ K. Briley,² P. Bolin,² S. Kendrick,³ H. Jones,³ K. McLawhorn,³ A. Maldonado,⁴ C. Haisch,² D. Leeser,² L. Rebellato.²
¹Terasaki Research Institute, Los Angeles; ²East Carolina University, Greenville, NC; ³Eastern Nephrology Associates, Greenville, NC; ⁴Vidant Medical Center, Greenville, NC.
Introduction: We have recently shown that immunosuppression reduction with BK virus is associated with the development of de novo donor anti-human leukocyte antigen-specific antibodies (dnDSA).…
2018 American Transplant Congress
Infectious Complications Associated with Eculizumab Used for ABO-Incompatible Renal Transplantation
M. Campara, P. West-Thielke, K. Progar, N. Jasiak, A. Lichvar, I. Tang, E. Benedetti.
University of Illinois at Chicago, Chicago.
Introduction: A novel approach in ABO-incompatible (ABOi) living donor renal transplant (LDRT) includes use of eculizumab (ECU) that allows for avoidance of traditional desensitization. We…
2018 American Transplant Congress
Recipient Outcomes in Age Mismatched Living Kidney Transplants from Donors > 60 Years: A UNOS Database Analysis
O. Adebiyi, A. Riaz, M. Yaqub, D. Mishler, T. Taber, A. Sharfuddin.
Indiana University, Indianapolis.
Background: Donor and recipient age mismatch kidney transplantation are known to affect graft survival. We examined the impact of age mismatching on graft survival after…
2018 American Transplant Congress
Highly Correlative Whole-Tissue Gene/protein Signatures to Score FFPE Transplant Biopsies with Inflammation and Acute Rejection
T. Sigdel, M. Nguyen, D. Dobi, S-.C. Hsieh, J. Liberto, F. Vincenti, Z. Laszik, M. Sarwal.
Unversity of California San Francisco, San Francisco.
Background: We have previously reported the quantification of a common immune response module (CRM) of 11 genes to identify and score acute rejection (AR) across…