2018 American Transplant Congress
IL23R is a Pathogenic Gene in Type 1 Regulatory T Cells during Mouse Cardiac Transplantation Models
IL23R has been confirmed to be a pathogenic gene in Th17 cells. However, its role in type 1 regulatory T cells (Tr1 cells) is not…2018 American Transplant Congress
Low Intensity Conditioning Protocol for Inducing Chimerism-Based Tolerance in Non-Obese Diabetic Mice
Institute for Cellular Therapeutics, University of Louisville, Louisville, KY.
Type 1 diabetes is the most common chronic disease affecting children. Islet cell or pancreas transplantation offer the most physiologic approach to glucose homostasis. However…2018 American Transplant Congress
An In Vitro Model of Human Antibody-Mediated Rejection Depicts Key Role for NK Cells
AIM: Antibody-mediated rejection (ABMR) is the leading cause of kidney allograft loss but its immune mechanisms are incompletely understood. We sought to examine key interactions…2018 American Transplant Congress
Peripheral but Not Follicular T Helper Cells Are Activated by Allogeneic Human Endothelial Cells under IRI-Like Conditions and Promote Donor Specific Antibody
Background: Perioperative ischemia reperfusion injury (IRI) is a consequence of solid organ allograft transplantation that primes the graft for future rejection.Methods: We developed an in…2018 American Transplant Congress
What Threshold MFI is the Luminex 1:8 Dilution the Poor Man's C1q for Patients Awaiting Heart Transplant?
Cedars Sinai Medical Center, Los Angeles.
Purpose: Heart transplant candidates are evaluated for anti-HLA antibodies by Luminex single-antigen bead testing to avoid donors that may harbor antigens that these antibodies are…2018 American Transplant Congress
The Secret is Selection of Muscular Dystrophy for Success after Heart Transplant
Cedars Sinai Medical Center, Los Angeles.
Purpose: Patients with muscular dystrophy may have an associated cardiomyopathy, resulting in advanced heart failure requiring transplantation. However, the skeletal muscle dysfunction can result in…2018 American Transplant Congress
Pancreas Decellularization Protocol – Comparison of Methods
Foundation of Research and Science Development, Otwock, Poland.
Background: Whole organ decellularization is gaining a lot of popularity since its development in tissue engineering. It is a process which allows to create complex…2018 American Transplant Congress
Prospective Validation of Prediction Models for Kidney Discard
A large number of kidneys are discarded every year despite evidence that many could have provided survival benefit for waitlisted candidates. Identifying kidneys at high…2018 American Transplant Congress
Ethnic Disparities in Elderly Patients Receiving Kidney Transplantation
Henry Ford Transplant Institute, Detroit, MI.
Purpose: Over the past 10 years, the number of elderly kidney transplant recipients has increased. This analysis evaluates whether the trend is equitable across ethnic…2018 American Transplant Congress
Cytomegalovirus Prophylaxis Following Alemtuzumab Induction in High Risk Renal Transplant Recipients Experiencing Delayed Graft Function
University of Maryland, Baltimore.
Purpose: There is limited data to support the use of valganciclovir in patients on dialysis. This study assessed the efficacy of valganciclovir 450 mg twice…
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