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American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Exploring the Viability of Kidneys Discarded in the US: A Comparison of Kidney Utilization Patterns and Outcomes in the US and France

    O. Aubert, P. Reese, M. Raynaud, D. Viglietti, C. Loheac, N. Kamar, M. Delahousse, C. Legendre, D. Glotz, C. Lefaucheur, A. Loupy.

    Paris Translational Center for Organ Transplantation, Paris, France.

    Approximately 2,000 donated kidneys are discarded in the US each year. Some transplant leaders have questioned the viability of these lost organs, while others suggest…
  • 2018 American Transplant Congress

    Time-Effect of Donor and Recipient Characteristics on Graft Survival after Kidney Transplantation

    E. Molmenti,1 J. Yang,3 C. Molmenti,2 E. Grodstein,1 H. Rilo,1 L. Teperman.1

    1Surgery, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY; 2Feinstein Institute, Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY; 3Epidemiology, Mailman Schoool of Public Health, Columbia University, New York, NY.

    BackgroundThe current kidney allocation system (KAS) is based on the Kidney Donor Profile Index (KDPI) and the Estimated Post-Transplant Survival (EPTS), quality-based “longevity matching” strategies…
  • 2018 American Transplant Congress

    12-Months Evolution of Anti-HLA Antibodies Donor Specific Antibodies after Rescue Switch from CNi-Based Immunosuppressive Regimen to Belatacept in Kidney Allograft Recipients

    M. Matignon,1 C. Dudreuilh,1 P. Rémy,1 J-.L. Taupin,2 P. Grimbert.1

    1Nephrology Transplantation, APHP Henri Mondor, Creteil, France; 2Histocompatibility, APHP Saint Louis, Paris, France.

    IntroductionAfter kidney transplantation, long-term immunosuppression with calcineurin inhibitors (CNIs) or mTOR inhibitors (mTORi) leads to adverse effects, such as nephrotoxicity and proteinuria. Currently, available data…
  • 2018 American Transplant Congress

    A Novel Combined Formula to Direct Optimal Immunosuppressive Drug Exposure in Renal Transplant Recipients

    O. Pankewycz,1 E. Onan,2 M. Laftavi,1 R. Gruessner,3 H. Smileuski,1 E. Alissandrello,1 A. Gruessner.3

    1Upstate Medical University, Syracuse, NY; 2Cukurova University, Adana, Turkey; 3Downstate Medical University, New York, NY.

    Purpose: The most widely used maintenance immunosuppressive combination after kidney transplantation is tacrolimus (TAC) and mycophenolic acid (MPA). The utility of therapeutic drug monitoring for…
  • 2018 American Transplant Congress

    Target Tacrolimus Troughs and CYP3A5 Polymorphisms Do Not Predict Therapeutic Drug Exposure in African American and Caucasian Renal Transplant Recipients

    K. Tornatore,1,4 K. Attwood,2 D. Brazeau,3 S. Chang,4 R. Venuto.4

    1Pharmacy, School of Pharmacy, University at Buffalo(UB), Buffalo; 2Biostatistics, RPCI, Buffalo; 3Pharmaceutical Sciences, University of New England, Portland; 4Nephrology, UB School of Medicine, Buffalo.

    Background: African American(AA) renal transplant recipients(RTR) require larger tacrolimus(TAC) doses to achieve similar troughs to Caucasians which may be due to CYP3A5 polymorphisms. TAC pharmacokinetics…
  • 2018 American Transplant Congress

    Variation in Living Donor Kidney Transplantation among U.S. Transplant Centers

    T. Melanson,1 M. Basu,1 L. Plantiga,1 S. Pastan,1 S. Mohan,2 R. Patzer.1

    1Emory University, Atlanta; 2Columbia University, New York.

    Introduction: Living donor kidney transplant (LDKTx) is the preferred treatment for patients with end-stage renal disease (ESRD) but continues to be less common than deceased…
  • 2018 American Transplant Congress

    Cumulative Sum Analysis of the Learning Curve for Video-Assisted Minilaparotomy Donor Nephrectomy in Healthy Kidney Donors

    J. Na,1 J. Park,1 M-.G. Yoon,1 H. Lee,2 Y. Yoon,3 K. Huh,4 M. Kim,4 S. Kim,4 Y. Kim,4 W. Han.1

    1Department of Urology, Yonsei University College of Medicine, Urological Science Institute, Seoul, Korea; 2Department of Urology, National Health Insurance Service Ilsan Hospital, Goyang-si, Korea; 3Department of Urology, Hanyang University Medical Center, Seoul, Korea; 4Department of Surgery-Transplantation, Yonsei University College of Medicine, Seoul, Korea.

    Background:Video-assisted minilaparotomy surgery (VAMS) is a hybrid of open and laparoscopic surgical techniques, so has advantages of both approaches. Here we examined the learning curve…
  • 2018 American Transplant Congress

    Temporal Trends in Living Kidney Donor Candidates

    S. Singh,1,2 V. DiCecco,2 M. Luo,2 Y. Li,2 O. Famure.2

    1Division of Nephrology, Department of Medicine, University of Toronto, Toronto, ON, Canada; 2Division of Nephrology and the Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.

    Living kidney donor transplantation is the preferred treatment option for end-stage renal disease. However, living kidney donation rates have plateaued in North America. Existing studies…
  • 2018 American Transplant Congress

    Torsion and Inversion of Intraperitoneal Kidneys Manifesting as Acute Allograft Dysfunction – A Case Series

    P. Kandula, A. Patel, S. Bains, H. Sun.

    Saint Barnabas Medical Center, Livingston, NJ.

    Torsion (rotation of kidney allograft around its vascular pedicle) or inversion (rotation of kidney graft around ureter) of intraperitoneal transplant kidney is a rare complication.…
  • 2018 American Transplant Congress

    Higher Concordance in the Incidence of DGF and Post-Transplant BKV Infection among Recipients Receiving Mate Kidneys from the Same Deceased Donor: A Paired Deceased Donor Kidney Transplant Analysis

    K. Venkatesh,1 C. Wu,1 C. Puttarajappa,1 R. Mehta,1 P. Sood,1 A. Tevar,2 S. Hariharan.1

    1Nephrology Division, Univ of Pittsburgh Medical Center, Pittsburgh, PA; 2Transplant Surgery, Univ of Pittsburgh Medical Center, Pittsburgh, PA.

    Background: This study was undertaken to explore the degree to which donor variables impact rates of DGF, post-transplant CMV and BKV infections using a paired…
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