ATC Abstracts

American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Long-Term Efficacy and Safety of Everolimus Based Immunosuppression on De Novo Kidney Transplantation with 9 Years Follow-Up

    S. Narumi,1 Y. Watarai,1 N. Goto,2 T. Hiramitsu,1 M. Okada,1 M. Tsujita,2 K. Futamura,2 M. Nishihira,3 T. Kobayashi.4

    1Transplant Surgery, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Aichi, Japan; 2Transplant Nephrology, Japanese Red Cross Nagoya Daini Hospital, Nagoya, Aichi, Japan; 3Nephrology, Masuko Memorial Hospital, Nagoya, Aichi, Japan; 4Renal Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan.

    Purpose: Long-term efficacy and safety of everolimus (EVR) based immunosuppression for de novo kidney transplant recipient who were involved in A1202 study was evaluated in…
  • 2018 American Transplant Congress

    Effect and Reasons of Rescue Switch to Belatacept among 73 Calcineurin-Inhibitors Treated Kidney Allograft Recipients – A Three Years Retrospective Cohort, Single Center Study

    M. Matignon,1 C. Dudreuilh,1 P. Rémy,1 D. Desvaux,2 P. Grimbert.1

    1Nephrology Transplantation, APHP Henri Mondor, Creteil, France; 2Pathology, APHP Henri Mondor, Creteil, France.

    IntroductionAfter kidney transplantation, long-term immunosuppression with calcineurin inhibitors (CNIs) or mTOR inhibitors (mTORi) leads to adverse effects, such as nephrotoxicity and proteinuria. Currently, available data…
  • 2018 American Transplant Congress

    Prolonged-Release Tacrolimus Dosing in De Novo Kidney Transplantation: Randomized, Open-Label, Pilot Study

    Y. Kim,1 Y. Chiang,2 S. Kim,3 M. Kim,4 S. Park,5 S. Wu,6 K. Horita,7 Y. Nakashima,7 H. Jiang,8 D. Han.1

    1Asan Medical Center, Seoul, Korea; 2Chang Gung Memorial Hospital-Linkou, Taoyuan City, Taiwan; 3Samsung Medical Center, Seoul, Korea; 4Severance Hospital, Seoul, Korea; 5Dongsan Medical Center, Daegu, Korea; 6Tri-Service General Hospital, Taipei City, Taiwan; 7Astellas Pharma, Inc., Tokyo, Japan; 8Astellas Pharma, Inc., Maao, Singapore.

    A multicenter, randomized, open-label, parallel-group, pilot, 52-wk study in Asian countries that assessed renal function, efficacy, and safety of low vs standard-dose prolonged-release tacrolimus (PRT)…
  • 2018 American Transplant Congress

    Making Right Donor Nephrectomy Great Again: Evaluating Right Hand Assisted Retroperitoneal Donor Nephrectomy

    H. Alahdal,1 F. Alghamdi,1 M. Shoukri,2 J. Brockmann,1 D. Broering.1

    1Kidney and Pancreas Transplantation, Organ Transplant Center, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia; 2Cell Biology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.

    Background: Living kidney transplant offers ideal therapy of end stage renal disease patients. A variety of minimal invasive techniques for donor nephrectomy have been described…
  • 2018 American Transplant Congress

    Analysis of Patient Reported Outcomes for Patients That Received Living Donor Kidney Transplants

    E. Venniro,1,2 J. Taylor.1,2

    1Center for Transplantation, University of Rochester Medical Center, Rochester, NY; 2Division of Nephrology, University of Rochester Medical Center, Rochester, NY.

    Purpose: Caring for subjective complaints is one of the most difficult aspects of any health care provider's job. These conditions in the transplant patient are…
  • 2018 American Transplant Congress

    Unilateral vs. Bilateral Dual Kidney Transplantation: University of Bologna Experience

    M. Del Gaudio,1 M. Ravaioli,1 C. Zanfi,1 V. Bertuzzo,1 L. Maroni,1 G. La Manna,2 G. Liviano,2 A. Siniscalchi,3 A. D'Errico,4 A. Pinna.1

    1Organ Insufficency and Transplantation/Transplantation Unit Prof. A.D. Pinna, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; 2Organ Insufficency and Transplantation Nephrology Unit G. La Manna, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; 3Organ Insufficency and Transplantation Intensive Care Unit Prof. S. Faenza, S.Orsola Malpighi Hospital University of Bologna, Bologna, Italy; 4Organ Insufficency and Transplantation Pathology Unit D'Errico, S.Orsola Malpighi Hospital University of Bologna, Bolgona, Italy.

    One option for using organs from donors with a suboptimal nephron mass, e.g. expanded criteria donors (ECD) kidneys, is dual kidney transplantation (DKT)Methods: Ninety-three DKT…
  • 2018 American Transplant Congress

    Y-Adapter Mediated Next Gen Sequencing of BKPyV from Archived FFPE Tissue

    E. Harake,1 W. Wu,2 J. Opp,2 E. Farkash.1

    1Pathology, Michigan Medicine, Ann Arbor; 2Michigan Medicine, Ann Arbor.

    Background: In a subset of renal transplant recipients with urothelial carcinoma, tumor cells show universal expression of BK Polyomavirus (BKPyV) proteins, a hallmark of oncoviruses.…
  • 2018 American Transplant Congress

    Early Association of Low Doses of Tacrolimus and a mTOR Inhibitor in BK Polyomavirus Infection in Kidney Transplant Recipients

    V. Lopez,1 T. Vazquez,1 C. Jironda,1 M. Cabello,1 E. Sola,1 M. Leon,2 E. Marques,1 D. Hernandez.1

    1Nephrology, Hospital Regional Malaga, Malaga, Spain; 2Pathology, Hospital Regional Malaga, Malaga, Spain.

    Introduction: BK polyomavirus (BKV) replication can be detected in up to 60% of kidney transplant recipients, with an incidence of nephropathy of 5-10%, leading to…
  • 2018 American Transplant Congress

    A Six-Month, Prospective, Single-Center, Pilot Study to Determine the Pharmacokinetics and Effectiveness of Immunosuppressant Regimens in Liver Transplantation Patients Receiving Twice-Daily Tacrolimus and Everolimus (TAC + EVR BID) Regimen Converted to Once-Daily Tacrolimus and Everolimus (TAC + EVR QD) Regimen – A Priliminary Report

    T-.H. Wu, C-.H. Cheng, Y-.C. Wang, C-.F. Lee, T-.J. Wu, H. Chou, K-.M. Chan, W-.C. Lee.

    Division of Liver and Transplantation Surgery, Chang-Gung Memorial Hospital, Chang-Gung University College of Medicine, Taoyuan, Taiwan.

    Adherence to immunosuppressant regimen is crucial for graft survival and usually inversely related to the dose frequency. Similar efficacy and safety profile has been approved…
  • 2018 American Transplant Congress

    Outcomes of Liver Transplantation for Hepatic Epithelioid Hemangioendothelioma in the U.S. (2002-2015)

    T. Bittermann,1 S. Prenner,1 P. Abt,2 D. Goldberg.1,3

    1Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; 2Division of Transplant Surgery, University of Pennsylvania, Philadelphia, PA; 3Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA.

    Hepatic epithelioid hemangioendothelioma (HEHE) is a rare, malignant vascular tumor of the liver with high mortality if left untreated. Liver transplantation (LT) is potentially curative,…
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