Am J Transplant, Volume 18, Suppl 3 Archives - Page 132 of 211 - ATC Abstracts

2018 American Transplant Congress
Center Variation in Six-Month Post-Donation Follow-Up of Obese Living Kidney Donors
R. Reed,¹ P. MacLennan,¹ B. Shelton,¹ M. Mustian,¹ D. McWilliams,¹ J. Blackburn,² D. Sawinski,³ J. Locke.¹
¹Surgery, University of Alabama at Birmingham, Birmingham, AL; ²Health Care Organization & Policy, University of Alabama at Birmingham, Birmingham, AL; ³Medicine, University of Pennsylvania, Philadelphia, PA.
Introduction: While post-donation follow-up in the United States has improved since implementation of minimum center compliance standards, it is still suboptimal and brief (only 2…
2018 American Transplant Congress
Long-Term Risk of Solid Organ De Novo Malignancies after Liver Transplantation: A French National Study on 11226 Patients
O. Seree, M. Altieri, J. Dumortier, GReF2.
Réseau Régional de Cancérologie Onco-Basse Normandie, Herouville St-Clair, France; Service d'Hépato-Gastroentérologie, Nutrition et Oncologie Digestive, CHU CAEN Hôpital Côte de Nacre, Caen, France; Hospices Civils de Lyon, Lyon, France.
Background and aims: De novo malignancies are one of the major late complications and cause of death after liver transplantation (LT). Using extensive data from…
2018 American Transplant Congress
HIV, HBV, and HCV Screening with NAT and Serology in the OPO Setting
N. Theodoropoulos,¹ M. Ison.²
¹UMass Memorial Medical Center, Worcester, MA; ²Northwestern University, Chicago, IL.
Background:In December 2014, the Organ Procurement & Transplantation Network updated policy to mandate screening with nucleic acid tests (NAT) for hepatitis C virus (HCV) in…
2018 American Transplant Congress
Using the SRTR Expected Survival Worksheet to Estimate Expected Number of Events
J. Gregg,¹ K. Womer,¹ K. Andreoni.²
¹Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, FL; ²Department of Surgery, University of Florida, Gainesville, FL.
The purpose of this effort is to provide transplant administrative and clinical directors with reliable predictions of Scientific Registry of Transplant Recipients (SRTR) risk-adjusted 1-year…
2018 American Transplant Congress
Despite the Growing Impact of the American Opioid Epidemic on Organ Donation, a Small Percentage of Drug Intoxication Deaths Result in Organ Donation
L. Hickman,¹ J. Killian,¹ S. Windham.^1,2
¹Department of Surgery, University of Alabama at Birmingham, Birmingham, AL; ²Alabama Organ Center, Birmingham, AL.
Purpose: This study seeks to understand the regional variation in donations after drug overdose (DO) and quantify the proportion of DO deaths that go on…
2018 American Transplant Congress
In-Situ Tissue-Based Gene Expression Profiling is a Reliable Method to Detect Gene Transcripts in Human Kidney Transplant Biopsies
D. Dobi,¹ J. Henrik,² T. Sigdel,² A. Chen,¹ Z. Laszik.¹
¹Department of Pathology, University of California, San Francisco, San Francisco, CA; ²Department of Surgery, University of California, San Francisco, San Francisco, CA.
Purpose. Validation studies that would enable the clinical application of quantitative in situ tissue-based gene expression profiling in renal transplantation are lacking. In this study,…
2018 American Transplant Congress
Peripheral Blood Immune Response-Related Gene Analysis for Evaluating the Development of Subclinical Antibody-Mediated Rejection
T. Yamamoto,¹ K. Iwasaki,² K. Murotani,³ A. Takeda,⁴ M. Tsujita,⁴ T. Hiramitsu,⁴ N. Goto,⁴ S. Narumi,⁴ Y. Watarai,⁴ K. Uchida,² T. Kobayashi.⁵
¹Xenotransplantation, University of Alabama at Birmingham, Birmingham, AL; ²Kidney Disease and Transplant Immunology, Aichi Medical University, Nagakute, Japan; ³Biostatistics, Aichi Medical University, Nagakute, Japan; ⁴Kidney Center, Nagoya Daini Red Cross Hospital, Nagoya, Japan; ⁵Renal Transplant Surgery, Aichi Medical University, Nagakute, Japan.
Background: Noninvasive methods for the early diagnosis of chronic antibody-mediated rejection (cAMR) are desired for patients with de novo (dn) donor-specific HLA antibody (DSA) because…
2018 American Transplant Congress
Isolation and Profiling of miRNAs from Formalin Fixed Paraffin Embedded Endomyocardial Tissues from Human Heart Transplant Recipients
R. Nog,^1,2 C. Gupta,^1,2 J. Fallon,^1,2 J. Panza,^1,2 N. Haque.²
¹Westchester Medical Center, Valhalla, NY; ²New York Medical College, Valhalla, NY.
Allograft rejection is a common complication post heart transplant (HTx) and can be confirmed by endomyocardial biopsy (EBx) only. There is however an increasing need…
2018 American Transplant Congress
Molecular Classifiers Can Outperform the Flawed Histologic “Gold Standard” on Which They Are Trained
J. Reeve, P. Halloran.
University of Alberta, Edmonton, Canada.
The histologic diagnosis of rejection in organ transplants is known to be an imperfect gold standard. Therefore, it might be assumed that molecular classifiers built…
2018 American Transplant Congress
Cardiac Grafts from Insulin Resistant Donors Trigger a Heightened Immune Response via Excessive Induction of Autophagy
S. Cai,¹ J. Miao,² A. Chandraker.¹
¹Transplantation Research Center, Renal Division, Brigham and Women's Hospital, Boston, MA; ²Division of Endocrinology, Boston Children's Hospital, Boston, MA.
Background Heart transplantation remains the treatment of choice for many patients with medically refractory heart failure. The use of organs from patients with insulin resistant…