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American Transplant Congress abstracts

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  • 2018 American Transplant Congress

    Depressive Symptoms, Medication Nonadherence, and Clinical Outcomes Following Lung Transplantation

    M. C. Chu,1 P. J. Smith,2 G. L. Stonerock,2 J. A. Blumenthal.2

    1Duke-NUS Medical School, Singapore, Singapore; 2Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, NC.

    Background:Elevated depressive symptoms have been associated with worse clinical outcomes following lung transplantation, including mortality. Few studies, however, have examined the mechanisms or clinical correlates…
  • 2018 American Transplant Congress

    Liver Preservation with Machine Perfusion and a New Human-Derived Hemoglobin-Based Oxygen Carrier Solution (HDHBOC)

    W. R. Light,1 A. Malavalli,1 K. Vandegriff,1 P. Fontes.2

    1VirTech Bio, Inc, Natick, MA; 2University of Pittsburgh, Pittsburgh, PA.

    Introduction: Machine perfusion (MP) is becoming the new standard for liver preservation following the successful implementation of devices for kidney and lung preservation ex-vivo. Liver…
  • 2018 American Transplant Congress

    Allogeneic Mesenchymal Stem Cells as Induction Therapy Are Safe and Feasible in Renal Allografts: Pilot Results of a Multicenter Randomized Controlled Trial

    Q. Sun,1 F. Han,1 M. Zhao,2 R. Cao,3 D. Zhao,1 Z. Huang,1 L. Hong,1 Y. Peng,1 Q. Sun.1

    1Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China; 2Zhujiang Hospital, Southern Medical University, Guangzhou, China; 3Second Affiliated Hospital, Guangzhou Traditional Chinese Medicine University, Guangzhou, China.

    Background: Delayed graft function (DGF) and acute rejection lead to adverse effects on graft outcomes. Optimal induction intervention should include both renal structure injury repair…
  • 2018 American Transplant Congress

    NFkB Inhibitor Improves Glycemic Control after Syngeneic Islet Transplantation by Suppression of Proinflammatory and Apoptotic Gene Expression in a Cerulein-Induced Pancreatitis Model

    G. Yoshimatsu,1 C. Darden,2 K. Kumano,2 C. Chang,2 P. Saravanan,2 M. Lawrence,2 B. Naziruddin.3

    1Fukuoka University, Fukuoka, Japan; 2Baylor Scott and White Research Institute, Dallas; 3Baylor Simmons Transplant Institute, Dallas.

    Total pancreatectomy with islet autotransplantation (TPIAT) is an effective treatment for refractory chronic pancreatitis. Repeated or continuous pancreatitis attack leads islet damage beyond inflamed exocrine…
  • 2018 American Transplant Congress

    Two Years of the HOPE Act

    A. Wilk,1 C. Durand,2 D. Segev,2 D. Klassen.1

    1United Network for Organ Sharing, Richmond, VA; 2Johns Hopkins University, Baltimore, MD.

    The HOPE Act allows research on transplantation of organs from HIV+ donors into patients infected with HIV prior to transplantation. There are 42 kidney and…
  • 2018 American Transplant Congress

    Potential Living Donors Identified through Social Media

    S. Weeks, K. Kumar, J. Konel, E. King, M. Henderson, A. Cameron, J. Garonzik Wang.

    Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD.

    Purpose: We previously described a smartphone application that harnesses social media to increase potential living donors among kidney and liver transplant candidates. We compared potential…
  • 2018 American Transplant Congress

    Treatment of Post Transplant Hepatitis C (HCV) with Direct-Acting Antiviral (DAA) Agents May Improve Liver Function but Does Not Lead to an Increase in Liver Rejection

    P. Sheiner, N. Mello, G. Baixauli, M. Einstein, C. Rochon, Y. Kwon, M. Bejon.

    Surgery, Hartford Hospital, Hartford, CT.

    Previous studies have suggested that with the use of with (DAA) agents to treat post transplant (HCV), there has been an increased incidence of liver…
  • 2018 American Transplant Congress

    Survival Rates of Patients with Previous Cardiac Surgery Undergoing Lung Transplant

    H. Niikawa, T. Okamoto, K. Ayyat, Y. Itoda, K. McCurry.

    Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, OH.

    Background: Severe heart diseases are traditionally considered a contraindication for Lung transplantation (LTx). There are suggestions that patients with severe heart diseases undergoing LTx will…
  • 2018 American Transplant Congress

    Selection and Stratification of Anti-HLA-A and HLA-B Sensitized Patients in Pig-to-Human Xenotransplantation

    G. Martens,1 J. Ladowski,1 J. Butler,2 L. Reyes,1 M. Tector,1 A. Tector.1

    1University of Alabama at Birmingham, Birmingham, AL; 2Indiana University School of Medicine, Indianapolis, IN.

    Introduction: Patients with anti-HLA-A and –B antibodies are difficult to match and represent a possible population for inclusion in pig-to-human xenotransplantation clinical trials. Donor specific…
  • 2018 American Transplant Congress

    Use of HCV Ab+/NAT- Donors in HCV Naïve Renal Transplant Recipients

    A. Dao,1 M. Cuffy,1 T. Kaiser,1 A. Loethen,1 J. Cafardi,2 A. Shields,2 M. Cardi,2 R. Alloway,1 A. Govil,1 K. Sherman,1 S. Shah,1 E. Woodle.1

    1Univeristy of Cincinnati Medical Center, Cincinnati, OH; 2The Christ Hospital, Cincinnati, OH.

    The continued organ shortage in renal transplantation (RT) has stimulated use of organs from increased-risk donors to expand the donor pool. The rate of denovo…
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