Am J Transplant, Volume 18, Suppl 3 Archives - Page 132 of 211 - ATC Abstracts

2018 American Transplant Congress
Transplantation of DCD Livers vs. NDD and LDLT: Is There a Difference in Post-Transplant Kidney Dysfunction?
D. Kollmann,¹ S. Neong,¹ R. Rosales,¹ G. Sapisochin,¹ M. Bhat,¹ M. Cattral,¹ P. Greig,¹ L. Lilly,¹ D. McGilvray,¹ A. Ghanekar,¹ D. Grant,¹ M. Selzner,¹ F. Wong,² N. Selzner.¹
¹Multi Organ Transplant, Toronto General Hospital, Toronto, Canada; ²Division of Gastroenterology, Toronto General Hospital, Toronto, Canada.
Background. Recipients of donation after circulatory death (DCD) grafts are reportedly at higher risk of developing post liver transplant (LT) renal dysfunction. Our aim was…
2018 American Transplant Congress
Living Liver Donation: The Role of Facebook in Directed Donation
A. Lai, J. Steel, S. Ganesh, O. Ola, S. Shen, N. Zharichenko, S. Nawaz, A. Tevar, A. Humar.
Surgery, University of Pittsburgh, Pittsburgh, PA.
Background: The aims of this study were to understand the number and type of directed living liver donors who contacted the transplant team after learning…
2018 American Transplant Congress
Renal and Bone Safety in Post Liver Transplant Patients with Chronic Kidney Disease Receiving Tenofovir Alafenamide for HBV Prophylaxis
E. Gane,¹ B. George,¹ S. Munn,¹ H. Wang,² V. Suri,² A. Gaggar.²
¹Auckland City Hospital, Auckland, New Zealand; ²Gilead Sciences, Foster City, CA.
Background and Aims: Chronic Hepatitis B (CHB) remains a leading indication for orthotopic liver transplantation (OLT) globally. Common complications following OLT include renal dysfunction secondary…
2018 American Transplant Congress
Incisional Hernia after Orthotropic Liver Transplantation: A Systematic Review and Meta-Analysis
J. Butler, D. O'Brien, J. Kays, C. Kubal, B. Ekser, J. Fridell, R. Mangus, J. Powelson.
Transplant Surgery, Indiana University, Indianapolis, IN.
Background: Incisional hernia is a well-known complication of orthotopic liver transplantation. Despite wide recognition of the impact of this problem, the incidence remains imprecisely known.Methods…
2018 American Transplant Congress
Variation in Hypothermic Machine Perfusion Utilization and Clinical Outcomes for Deceased-Donor Kidneys
V. Krishnamoorthy,¹ S. Wunsch,² K. O'Connor,² M. Souter.³
¹Anesthesiology, Duke University, Durham, NC; ²LifeCenter Northwest, Bellevue, WA; ³Anesthesiology and Pain Medicine, University of Washington, Seattle, WA.
Introduction:Hypothermic machine perfusion (HMP) has been shown to be an effective method for preserving kidney allografts from deceased donors (1), but data suggests that low-risk…
2018 American Transplant Congress
Living-Donor Preemptive Kidney Transplant Timing Calculator: An Online Decision Support Tool
M. Barah,¹ M. Kurt,² A. Khojandi,¹ B. Tanriover.³
¹Industrial and Systems Engineering, Univeristy of Tennessee, Knoxville, TN; ²Economic and Data Sciences, Merck Research Labs, North Wales, PA; ³Division of Nephrology, UT Southwestern Medical Center, Dallas, TX.
Purpose: Optimal glomerular filtration rate (GFR) and timing for living preemptive kidney transplantation (PKT) is not well studied.Method: We developed an online engine to calculate…
2018 American Transplant Congress
Glycolytic Bias in mTORC2-Deficient Dendritic Cells Potentiates Antigen-Specific Immunity and Accelerates Graft Rejection
A. Watson,¹ H. Dai,¹ J. Diaz-Perez,² A. Menk,³ M. Killeen,² G. Delgoffe,³ A. Mathers,² A. Thomson.¹
¹Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; ²Dermatology, University of Pittsburgh, Pittsburgh, PA; ³Cancer Institute, University of Pittsburgh, Pittsburgh, PA.
The mechanistic target of rapamycin (mTOR) is known to function in two complexes: mTOR complex 1 (mTORC1) and mTORC2. While the function of mTORC1 in…
2018 American Transplant Congress
mRNA Transcript Profiles of 14 Genes in Plasma Exosome Predict Risk for Antibody-Mediated Rejection (ABMR) of Renal Allografts
H. Zhang,¹ E. Huang,² C. Nast,³ J. Kahwaji,² A. Vo,² S. Jordan,² M. Toyoda.¹
¹Transplant Immunology Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA; ²Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; ³Pathology, Cedars-Sinai Medical Center, Los Angeles, CA.
Background: Previously we reported that mRNA transcript profiles of 4 genes (gp130, SH2D1B, TNFα and CCL4) in plasma exosome could predict the risk of ABMR,…
2018 American Transplant Congress
Investigation of Lower Treatment Failure Rate Seen among Black Kidney Recipients on LCP-Tacrolimus vs. IR-Tacrolimus: Subgroup Analyses of Two Phase 3 Trials
T. Sparkes,¹ B. Masters,¹ C. Staino,² S. Patel,² M. Cooper.³
¹University of Maryland, Baltimore, MD; ²Veloxis, Cary, NC; ³Medstar Georgetown Transplant Institute, Washington, DC.
Black kidney transplant recipients are recognized as high risk for inferior allograft survival due to immunologic and non-immunologic factors. Pooled data from 2 Phase 3…
2018 American Transplant Congress
Inferior Patient and Graft Survival in Highly Sensitized Adult Kidney Transplant Recipients with a Prior Transplant Compared to Pediatric Kidney Transplant Recipients: An Analysis of OPTN Data
P. Almond,¹ S. Al-Akash,¹ D. Stewart,² A. Robinson.²
¹CPSST Departments of Pediatric Surgery and Renal Transplantation, Driscoll Children's Hospital, Corpus Christi, TX; ²UNOS, Richmond, VA.
Under the current kidney allocation system (KAS), pediatric (PED) renal transplant (RTx) candidates have a priority to kidneys from KDPI <35% donors. However, that excludes…