2018 American Transplant Congress
Gastrointestinal Autologous Reconstruction for Management of Chronic Gut Failure in the New Era of Visceral Transplantation
Center for Gut Rehabilitation & Transplantaion, Cleveland Clinic Foundation, Cleveland, OH.
OBJECTIVE(S): Chronic gut failure(CGF) is associated with life-threatening complications, impaired life-quality, and burdened healthcare-cost. With recent advances in autologous-reconstruction along with visceral transplantation, evidence-based practical…2018 American Transplant Congress
Prophylaxis of Wound Infections- Antibiotics in Renal Donation (POWAR): A Multicentre UK Double Blinded Placebo Controlled Randomised Controlled Trial
Abdominal Transplant Unit, Guy's Hospital, London, United Kingdom.
AIM: Postoperative infection following hand assisted laparoscopic donor nephrectomy (HALDN) confers significant morbidity. Previous reports suggest 1 in 5 patients develop infective complications. No modifiable…2018 American Transplant Congress
DAP12 and Its Triggering Co-Receptor TREM2 Play Key Roles in Regulation of Mouse and Human Liver DC Function and Control of Liver Ischemia-Reperfusion Injury
Background: Liver interstitial dendritic cells (DCs) have been implicated in the control of liver ischemia/reperfusion injury (IRI) and in the induction of liver transplant tolerance.…2018 American Transplant Congress
Predicting Survival after Deceased-Donor Kidney Transplants by Donor-Recipient Match: Who Can Tolerate a High-KDPI Kidney?
Johns Hopkins School of Medicine, Baltimore, MD.
Deceased-donor kidney transplantation (DDKT) with high-KDPI kidneys carries an additional risk of mortality and graft failure, which could be tolerable for some candidates but detrimental…2018 American Transplant Congress
Transplantation of Kidneys from Hepatitis C Virus (HCV) Antibody (Ab) Positive, NAT Negative Donors to HCV Negative Patients Results in Seroconversion but Not Viral Transmission
Transplant Surgery, Loma Linda University Health, Loma Linda, CA.
Anecdotal reports have suggested that transplantation of HCV Ab+/NAT- donor kidneys into HCV negative recipients is safe and not associated with HCV transmission. With the…2018 American Transplant Congress
Endothelin-1 Type A Receptor Antibodies Are Associated with Elevated Il-8, Arteritis and Decline in Renal Function in Pediatric Renal Transplant Recipients
1University of California, Los Angeles, Los Angeles, CA; 2Duke University, Durham, NC.
Background: We have recently shown that the non-HLA antibody, AT1R-Ab, is prevalent and associated with poor outcomes in pediatric kidney transplant recipients (KTRs). The prevalence…2018 American Transplant Congress
Impact of Changes to the LAS Calculation
Purpose: On 2/19/2015 major revisions to the Lung Allocation Score (LAS) calculation were made to more appropriately reflect candidates' waiting list urgency and post-transplant survival.…2018 American Transplant Congress
Human Thrombomodulin Expression on Genetically Modified Donor Pigs is Required to Maintain the Anti-Coagulation Profile
Introduction: Coagulation dysregulation is major limitation for xenotransplantation but it is resolved to some extent by making genetically engineered (GE) pigs, which express complement inhibitors…2018 American Transplant Congress
Treatment Outcomes of Recurrent Primary Focal Segmental Glomerulosclerosis (FSGS) after Kidney Transplantation
Introduction: Primary FSGS can recur in the renal allograft and is associated with poor graft outcomes. There is no established therapeutic intervention to prevent or…2018 American Transplant Congress
Precision Medicine for Determining the Efficacy of a Novel Belatacept Regimen
Transplant Nephrology, UCSF, San Francisco, CA.
IntroBelatacept is increasingly used as maintenance immunosuppression to improve long term outcomes in kidney transplant. Since acute rejection in patients on belatacept have been noted…
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