Am J Transplant, Volume 18, Suppl 3 Archives - Page 125 of 211 - ATC Abstracts

2018 American Transplant Congress
Development of a Predictive Model for Deceased Donor Organ Yield
W. Marrero Colon,¹ M. Lavieri,¹ S. Guikema,¹ D. Hutton,² N. Parikh.³
¹Industrial and Operations Engineering, University of Michigan, Ann Arbor, MI; ²School of Public Health, University of Michigan, Ann Arbor, MI; ³Department of Internal Medicine, University of Michigan, Ann Arbor, MI.
Organ transplantation is a lifesaving intervention for patients with organ failure. However, there is a gap between the supply and demand of organs in the…
2018 American Transplant Congress
Isolated Pancreas Transplantation: Does Rank List Position Matter for Imported Grafts?
J. Adler, R. Redfield, D. Kaufman, J. Odorico.
Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
INTRODUCTION: Pancreata are frequently not recovered or are discarded, resulting in a very low national utilization (~15%). There are many reasons why a transplant center…
2018 American Transplant Congress
Waiting List Outcomes for Patients Registered for Simultaneous Pancreas and Kidney Transplantation
V. Surendrakumar,^1,2 J. Richards,^1,2 M. Hossain,² G. Pettigrew.^1,2
¹Department of Surgery, University of Cambridge, Cambridge, United Kingdom; ²Department of Surgery, Addenbrooke's Hospital, Cambridge, United Kingdom.
IntroductionSimultaneous pancreas and kidney transplantation (SPK) offers a survival advantage to diabetic kidney patients over deceased donor renal transplantation alone. Whereas outcomes for SPK transplantation…
2018 American Transplant Congress
Early Predictors of Metabolic Outcomes in TPIAT
M. Kanak,¹ Y. Shindo,¹ M. Levy.^1,2
¹Surgery, Virginia Commonwealth University, Richmond, VA; ²Hume-Lee Transplant Center, VCU Health System, Richmond, VA.
BackgroundTotal Pancreatectomy with Islet Auto-transplantation (TPIAT) has been actively performed on patients with severe, debilitating pain of chronic pancreatitis or recurrent acute pancreatitis. It is…
2018 American Transplant Congress
Inter-Correlations between Psycho-Social Pre-Transplant Determinants of Post-Transplant Kidney Allograft Function
S. Shah, A. Gamilla-Crudo, B. Schreiber, C. Machner, O. Aleter, M. Mujtaba.
Transplant Services, UTMB, Galveston, TX.
Psycho-social factors are common in patients with advanced and end stage kidney disease and they may be associated with post kidney transplant outcomes. The aim…
2018 American Transplant Congress
Long-Term Nonhuman Primate Renal Allograft Survival without Ongoing Immunosuppression in Recipients of Delayed Donor Bone Marrow Transplantation
K. Hotta, T. Oura, A. Dehnadi, M. Matsunami, I. Rosales, R. Smith, R. Colvin, A. Cosimi, T. Kawai.
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA.
Background: We have previously reported induction of renal allograft tolerance in nonhuman primates following an initial post-transplant period of conventional immunosuppression (IS) using a nonmyeloablative…
2018 American Transplant Congress
Post-Transplant High Dose Cyclophosphamide Treatment Induces Thymus-Independent Immune Tolerance of Vascularized Composite Allografts via Complete Depletion of the Alloreactive TCR Repertoire.
G. Furtmüller,¹ B. Oh,¹ J. Sidhom,² M. Fryer,¹ V. Malek,¹ X. Zhou,¹ D. Cooney,¹ C. Brayton,³ J. Dodd-o,⁴ S. Ganguly,² G. Raimondi,¹ W. Lee,¹ L. Luznik,² G. Brandacher.¹
¹Plastic and Reconstructive Surgery, Johns Hopkins University, Baltimore, MD; ²Sidney Kimmel Cancer Center, Johns Hopkins University, Baltimore, MD; ³Department for Comparative Pathobiology, Johns Hopkins University, Baltimore, MD; ⁴Department of Anesthesiology, Johns Hopkins University, Baltimore, MD.
Background: Treatment with PT/Cy in the setting of combined donor bone marrow transplantation and VCA has shown encouraging results with regards to chimerism induction and…
2018 American Transplant Congress
Tipping the “Immune Balance” towards Tolerance by Specific and Systematic Depletion of Donor and Host Effector Cells
R. Bascom, K. Tao, L. West.
Alberta Transplant Institute, Canadian National Transplant Research Program, University of Alberta, Edmonton, Canada.
Purpose: To induce robust transplant tolerance in neonates with fully allogeneic spleen and bone marrow cells (SC/BMC) it is crucial to define the complex interplay…
2018 American Transplant Congress
The Relative Immunogenicity of HLA Mismatches in Adult Liver Transplant Recipients
V. Jucaud,¹ A. Shaked,² M. DesMarais,³ P. Sayre,³ M. Everly.¹
¹Terasaki Research Institute, Los Angeles, CA; ²University of Pennsylvania, Philadelphia, PA; ³Immune Tolerance Network, Seattle, WA.
Determining the immunogenicity of HLA mismatches (MM) may help preventing the appearance of de novo DSA (dnDSA) and avoiding antibody-mediated injuries.We studied the development of…
2018 American Transplant Congress
An In Vitro Model of Human Antibody-Mediated Rejection Depicts Key Role for NK Cells
L. Hidalgo,¹ M. Racape,² A. Loupy,² C. Lefaucheur.²
¹Lab. Med. and Pathology, University of Alberta, Edmonton, AB, Canada; ²Paris Cardiovascular Research Center INSERM, Paris, France.
AIM: Antibody-mediated rejection (ABMR) is the leading cause of kidney allograft loss but its immune mechanisms are incompletely understood. We sought to examine key interactions…