Am J Transplant, Volume 18, Suppl 3 Archives - Page 125 of 211 - ATC Abstracts

2018 American Transplant Congress
Living Liver Donor Follow-Up: Fewer Than Half of Centers Meet Follow-Up Requirements in the US
A. Thomas, C. Holscher, A. Shaffer, J. Garonzik-Wang, A. Massie, D. Segev, M. Henderson.
JHU, Baltimore.
OPTN/UNOS began requiring 1-year living donor follow-up (LDF) for living liver donors (LLDs) in 2014. Compliance with a similar policy for living kidney donors was…
2018 American Transplant Congress
T Cell Exhaustion in Kidney Transplant Patients
M. Fribourg,¹ C. Fischman,² L. Anderson,² B. Burrell,³ P. Heeger,² P. Cravedi.²
¹Department of Neurology, Icahn School of Medicine, New York; ²Department of Medicine, Icahn School of Medicine, New York; ³Immune Tolerance Network, Bethesda.
Background: T cell exhaustion is a dysfunctional state that arises during chronic infection and cancer in response to persistence of high antigenic load. Whether chronic…
2018 American Transplant Congress
Donor Liver Apoptosis is Associated with Early Allograft Dysfunction and Short-Time Graft Survival after Liver Transplantation
Z. Guo, Z. Zhu, Y. Tang, S. Huang, Z. Zhang, X. He, G. Chen.
Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.
Aims The aim of the study was to determine whether donor liver apoptosis is predictive for early allograft dysfunction (EAD) and graft survival after liver…
2018 American Transplant Congress
Time in Therapeutic Range Predicts DSA Development and Acute Rejection in Kidney Recipients with High Tacrolimus Coefficient of Variation
S. Davis, J. Gralla, P. Klem, A. Wiseman, J. Cooper.
University of Colorado, Aurora, CO.
High tacrolimus trough coefficient of variation (TAC CV) has been associated with an increased risk of de novo donor-specific antibody (dnDSA) and acute rejection (AR).…
2018 American Transplant Congress
What Deceased Donors Do KPD Candidates Accept?
A. Toll,¹ R. Leishman,¹ V. Casingal,² M. Aeder,³ T. Sandholm,⁴ N. Turgeon.⁵
¹UNOS, Richmond, VA; ²Carolinas HealthCare Sys, Charlotte, NC; ³Univ Hosp Med Ctr, Cleveland, OH; ⁴Carnegie Mellon Univ, Pittsburgh, PA; ⁵Emory Univ, Atlanta, GA.
Background: Possible utilization of deceased donors (DDs) to initiate KPD chains has been of interest to the transplant community. OPTN KPD candidates are required to…
2018 American Transplant Congress
Liver Transplant Survival Index for Recipients with High MELD Score: A Model for Post-Transplant Survival in Severely Ill Patients
J. Steggerda,¹ M. Bloom,¹ C. Bresee,² D. Malinoski,³ A. Klein,¹ K. Kim.¹
¹Surgery, Cedars-Sinai Medical Center, Los Angeles, CA; ²Biostatistics, Cedars-Sinai Medical Center, Los Angeles, CA; ³Surgery, Oregon Health Science University, Portland, OR.
Background: SHARE-35 prioritizes patients with MELD scores ≥35 for regional sharing of liver allografts. Because this policy incentivizes transplantation of sicker patients, this study examines…
2018 American Transplant Congress
Enteric Conversion after Bladder-Drained Pancreas Transplantation: The Wisconsin Experience
J. Adler, R. Redfield, D. Kaufman, J. Odorico, H. Sollinger.
Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI.
INTRODUCTION: In the early experience of pancreas transplantation, bladder drainage was favored. However, this often caused metabolic and infectious complications that necessitated conversion to enteric…
2018 American Transplant Congress
Urinary C5b-9 is an Independent Predictor of Graft Failure in Renal Transplant Recipients
R. Lammerts, M. Eisenga, M. Alyami, M. Seelen, M. Daha, J. van den Born, S. Bakker, S. Berger, On behalf of the COMBAT Comsortium.
Department of Nephrology, University Medical Centre Groningen, Groningen, Netherlands.
IntroductionChronic antibody-mediated rejection is thought to be the main cause of late kidney-allograft loss, involving donor-specific antibody–mediated activation of the complement system. Activation of filtered…
2018 American Transplant Congress
Not All HLA Mismatches Are Equal: Determining the Relative De Novo DSA Induction Capacity of HLA Mismatches
V. Jucaud,¹ L. Rebellato,² K. Briley,² A. Maldonado,³ C. Haisch,² P. Bolin,² S. Kendrick,⁴ H. Jones,⁴ K. McLawhorn,⁴ D. Leeser,² M. Everly.¹
¹Terasaki Research Institute, Los Angeles, CA; ²East Carolina University, Greenville, NC; ³Vidant Medical Center, Greenville, NC; ⁴Eastern Nephrology Associates, Greenville, NC.
We studied the immunogenicity, defined as the development of de novo DSA (dnDSA), of HLA-A, -B, -DR and -DQ MM (serological) in a cohort of…
2018 American Transplant Congress
Center Variation in Six-Month Post-Donation Follow-Up of Obese Living Kidney Donors
R. Reed,¹ P. MacLennan,¹ B. Shelton,¹ M. Mustian,¹ D. McWilliams,¹ J. Blackburn,² D. Sawinski,³ J. Locke.¹
¹Surgery, University of Alabama at Birmingham, Birmingham, AL; ²Health Care Organization & Policy, University of Alabama at Birmingham, Birmingham, AL; ³Medicine, University of Pennsylvania, Philadelphia, PA.
Introduction: While post-donation follow-up in the United States has improved since implementation of minimum center compliance standards, it is still suboptimal and brief (only 2…