Am J Transplant, Volume 18, Suppl 3 Archives - Page 122 of 211 - ATC Abstracts

2018 American Transplant Congress
Economic Evaluation of Contemporary Kidney Transplant Practice
D. Axelrod,¹ M. Schnitzler,² H. Xiao,² W. Irish,³ J. Tuttle-Newhall,³ S-.H. Chang,⁴ B. Kasiske,⁵ T. Alhamad,⁴ K. Lentine.²
¹Lahey Clinic, Burlington; ²Saint Louis University, St. Louis; ³East Carolina University, Greeneville; ⁴Washington University, St. Louis; ⁵Hennepin County, Minneapolis.
Kidney transplantation (KTx) has been established as the optimal therapy for medically suitable patients with end-stage renal disease, prolonging survival and reducing health care spending.…
2018 American Transplant Congress
Information Needs of Adolescent Transplant Recipients Transitioning to Adult Care
B. Kosmach-Park,¹ D. Shellmer,² C. Nguyen,³ G. Mazariegos.²
¹Department of Transplant Surgery, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; ²Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA; ³Department of Pediatric Nephrology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.
Background: As adolescent and young adult (AYA) tx recipients transition to adulthood, a parallel transition in care is essential. The AYA should achieve skills for…
2018 American Transplant Congress
Activity Nanosensors for Early and Noninvasive Detection of Acute Organ Transplant Rejection
Q. Mac,¹ D. Mathews,² J. Kahla,¹ C. Stoffers,¹ O. Delmas,¹ B. Holt,¹ A. Adams,² G. Kwong.¹
¹Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA; ²Department of Surgery, Emory University School of Medicine, Atlanta, GA.
Purpose: We engineered activity nanosensors that sense anti-allograft T cell activity in vivo to noninvasively detect the onset of acute cellular rejection from urine.Methods: Granzyme…
2018 American Transplant Congress
IL-21 Regulates Creation of Tertiary Lymphoid Organs in Chronic Allograft Rejection
J. Breidenbach, C. Baum, P. Schroder, S. Stepkowski.
Medical Microbiology and Immunology, University of Toledo College of Medicine and Life Science, Toledo, OH.
Background: IL-21 is a cytokine expressed almost exclusively by cells of the adaptive immune system, making it an attractive target for reducing chronic allograft rejection…
2018 American Transplant Congress
Early Steroid Withdrawal and Kidney Transplant Outcomes for Recipients with Delayed Graft Function
S. Bae, A. Massie, X. Luo, J. Garonzik Wang, D. Segev.
Johns Hopkins, Baltimore, MD.
Current guidelines suggest early steroid withdrawal (ESW) regimen for kidney transplant (KT) recipients with low immunological risk. Delayed graft function (DGF) is a risk factor…
2018 American Transplant Congress
The Advantage of Utilizing ABO and HLA Compatible Pairs in Kidney Paired Donation
A. Basu,¹ C. Kosberg,¹ H. Khamash,² M. Mai,³ M. Prieto,¹ C. Schinstock.¹
¹Nephrology and Hypertension, Mayo Clinic, Rochester, MN; ²Nephrology and Hypertension, Mayo Clinic, Scottsdale, AZ; ³Nephrology and Hypertension, Mayo Clinic, Jacksonville, FL.
BACKGROUND: Kidney paired donation (KPD) programs are mainly used to facilitate transplantation for candidates with ABO or HLA incompatible living donors. However, the benefit of…
2018 American Transplant Congress
Viral-Specific Cytotoxic T-Cell (Viral-Tc) Responses in Highly-HLA-Sensitized Patients (HS) Maintained on Tacrolimus and Everolimus Post-HLAi Kidney Transplant
S. Ge,¹ M. Chu,¹ A. Karasyov,¹ D. Lovato,¹ J. Kahwaji,² A. Vo,¹ J. Choi,¹ S. Louie,¹ S. Jordan,¹ M. Toyoda.¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; ²Kidney Transplantation, Kaiser Permanente Medical Center, Los Angeles, CA.
Introduction: Viral infections represent significant infectious complications post- kidney transplant which may be increased with desensitization. CMV, EBV and BKV infections are the most prevalent.…
2018 American Transplant Congress
Program-Specific Survival from Listing: Variability and Association with Pretransplant and Posttransplant Metrics
A. Wey, N. Salkowski, B. Kasiske, A. Israni, J. Snyder.
SRTR, Minneapolis.
Transplant program performance assessment has traditionally focused on posttransplant outcomes. However, the survival benefit conferred by transplant offers a compelling reason to broaden program assessment…
2018 American Transplant Congress
Prospective Multicenter Validation of Human Transitional B Cell Cytokines as a Predictive Biomarker in Renal Transplantation
A. Cherukuri,¹ D. Chittka,¹ A. Sharma,¹ A. Salama,² C. Magee,² D. Rothstein.¹
¹UPMC, Pittsburgh; ²UCL, London, United Kingdom.
In renal transplantation, non-invasive biomarkers are needed to identify patients at risk for poor outcomes and guide pre-emptive therapy. Here, we assessed B cell cytokines…
2018 American Transplant Congress
A Low Level of De Novo DSA Sialylation is Associated with a Decreased of Allograft Survival in Non-Sensitized Kidney Transplant Recipients
M. Bonnet,^1,2 V. Pernin,^1,3 J-.E. Serre,¹ V. Georgescu,⁴ M. Le Quintrec,^1,2,3 G. Mourad,^1,2 J-.F. Eliaou,^2,5 C. Rene.^2,5
¹Nephrology, Dialysis and Transplantation, Hôpital Lapeyronie, Montpellier University Hospital, Montpellier, France; ²University of Medicine, Montpellier University, Montpellier, France; ³Inserm U1183, IRMB, Hôpital Saint Eloi, Montpellier University Hospital, Montpellier, France; ⁴Department of Medical Information, Montpellier University Hospital, Montpellier, France; ⁵Department of Immunology, Hôpital Saint Eloi, Montpellier University Hospital, Montpellier, France.
Background. In kidney transplantation, de novo donor specific antibodies (dnDSA) are associated with antibody-mediated rejection (ABMR) and graft failure. While appearance of dnDSA, there is…