2018 American Transplant Congress
Cognition and Self-Management in Liver Transplant Recipients
1Vanderbilt University, Nashville; 2University of Wisconsin-Madison, Madison.
Cognitive impairment in the liver transplant (LT) population could negatively affect one's ability to self-manage. This study examined cognition and its relationship with self-management in…2018 American Transplant Congress
Acquired Resistance to Transplantation Tolerance as a Result of Prior Pregnancy Requires B Cells
Introduction: Clinical data suggest allogeneic pregnancy is a sensitizing event; yet, recent data from mouse models indicates it induces fetal-specific regulatory T cell (Treg) expansion…2018 American Transplant Congress
Respiratory Viral Infections Induces Exosomes and Antibodies to Lung Self-Antigens, Kα1Tubulin and Collagen V, Following Human Lung Transplantation
Respiratory viral infection (RVI) following human lung transplantation (LTx) increases the risk for chronic rejection. We demonstrated that lung transplant recipients (LTxR) with acute and…2018 American Transplant Congress
Impact of KDPI and CPRA on Outcomes in Kidney Transplant Recipients
Cedars Sinai Medical Center, Los Angeles.
Introduction: The new KAS has led to a marked increase in kidney transplants among highly sensitized recipients, mostly attributable to higher allocation of low KDPI…2018 American Transplant Congress
The Etiologies and Impact of Hospitalization in Older Kidney Transplant Recipients
Medical University of South Carolina, Charleston, SC.
Older kidney transplant recipients (KTR) face challenges of post-transplant complications related to frailty and comorbidities. They are particularly vulnerable to infectious complications. This study elucidates…2018 American Transplant Congress
The Risk Factors of Acute Rejection in Patients with BK Nephropathy after the Reduction of Immunosuppression
Background: BK nephropathy (BKN) affects graft function and increases the risk of graft failure. The reduction of immunosuppression is the main treatment for BKN. However,…2018 American Transplant Congress
Cost Effectiveness of Lifelong Medicare Immunosuppressant Drug Coverage for Kidney Transplant Recipients in the Current Era
While there is no Medicare time limit for dialysis patients, kidney transplant recipients lose their Medicare coverage 36 months after they receive their transplant. The…2018 American Transplant Congress
Recipient IFNAR1 Signaling Supports Costimulation Independent Rejection by Promoting T Cell Activation
Department of Surgery, Emory University, Atlanta, GA.
Costimulation blockade (CoB) is a promising strategy for more targeted/less toxic transplant immunosuppression which has led to the first improvement in long-term outcomes for transplant…2018 American Transplant Congress
Curative Correction of FAH Deficiency by Chimeric Stem Cells Transplantation
Fumarylacetoacetate hydrolase (FAH) deficient pigs have been proposed as surrogate hosts for large scale in vivo expansion of normal FAH+ hepatocytes. However, immunologic rejection prevents…2018 American Transplant Congress
Follow Up of Patients Treated with the IgG Endopeptidase (IdeS) for Desensitization and HLA Incompatible (HLAi) Kidney Transplantation
Introduction:Donor-specific antibodies (DSAs) create an immunologic barrier to transplantation. This prevents transplantation for a significant percentage of highly-HLA sensitized patients (HS). Current desensitization therapies are…
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