Am J Transplant, Volume 18, Suppl 3 Archives - Page 109 of 211 - ATC Abstracts

2018 American Transplant Congress
Inhibition of Neutrophil Recruitment and Activation Protects Airway Epithelium after Transplantation
R. Zhang,¹ H. Fang,¹ Q. Chen,² J. Ochando,³ Y. Ding,¹ J. Xu.¹
¹Department of Immunology, Capital Medical University, Beijing, China; ²Department of Thoracic Surgery, Chaoyang Hospital, Beijing, China; ³Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.
Background: Obliterative bronchiolitis (OB) is the major obstacle limiting long-term allograft survival of lung transplantation. Airway epithelium is the primary target in obliterative airway diseases.…
2018 American Transplant Congress
Significance of Antibody-Mediated Vascular Rejection (AMVR) on Graft Survival: Correlation with Pure Antibody-Mediated Rejection (AMR)
B. Ozdemir,¹ F. Ozdemir,² A. Terzi,² G. Ozdemir,¹ A. Ok Atilgan,¹ E. Ayvazoglu Soy,³ A. Akdur,³ G. Moray,³ M. Haberal.³
¹Pathology, Baskent University, Ankara, Turkey; ²Nephrology, Baskent University, Ankara, Turkey; ³Transplantation, Baskent University, Ankara, Turkey.
Introduction: The importance of the endarteritis on graft survival in recipients with AMR is controversial. Thus we aimed to understand the prognostic value of the…
2018 American Transplant Congress
Early Experience Using Donor-Derived Cell-Free DNA for Detection of Rejection in Kidney Transplantation
E. Huang, A. Vo, J. Choi, A. Peng, S. Sethi, R. Najjar, S. Jordan.
Medicine/Nephrology, Cedars Sinai Medical Center, Los Angeles, CA.
Introduction:Donor-derived cell free DNA (ddDNA; Allosure, CareDX) has been validated as a non-invasive test that can discriminate rejection from non-rejection in kidney transplantation, but has…
2018 American Transplant Congress
Is the NETos Increased in Acute Antibody Mediated Rejection?
R. Villca-Gonzales,¹ J. Torres-Ruiz,² D. Gomez-Martin,² J. Alberu,³ L. Morales-Buenrostro.¹
¹Nephrology, Inst. Nacional de Ciencias Médicas y Nutrición SZ, Mexico City, CDMX, Mexico; ²Immunology, Inst. Nacional de Ciencias Médicas y Nutrición SZ, Mexico City, CDMX, Mexico; ³Transplantation, Inst. Nacional de Ciencias Médicas y Nutrición SZ, Mexico City, CDMX, Mexico.
Neutrophils can promote graft inflammation through a form of programmed cell death termed "NETosis". How alloantibodies contribute to neutrophil responses in grafts is not clear…
2018 American Transplant Congress
Haematological Autoimmune Disorders Associated with Alemtuzumab Induction in Renal and Simultaneous Pancreas and Kidney Recipients
A. Kousios,¹ R. Charif,¹ M. Atta,² A. Luqmani,² N. Cooper,² D. Taube.¹
¹Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom; ²Department of Haematology, Imperial College NHS Trust, London, United Kingdom.
Introduction Haematological Autoimmune Disorders (HAD) have been associated with Alemtuzumab (Az); namely immune thrombocytopenia (ITP), autoimmune haemolytic anaemia (AIHA), Evans syndrome (ES) and Red Cell…
2018 American Transplant Congress
Transplant Candidates and Potential Living Kidney Donors Are Supportive of Reciprocity for Transplant Candidates Who Participate in Kidney Paired Donation with a Compatible Donor
J. Gill,¹ J. Gill,¹ F. Ballesteros,² M. Fortin.²
¹UBC, Vancouver, Canada; ²Centre de Recherche du CHUM, Montreal, Canada.
The inclusion of compatible pairs in kidney paired donation (KPD) is a strategy to increase transplantation for incompatible pairs in KPD. We proposed a reciprocity…
2018 American Transplant Congress
Outpatient Prophylactic Valganciclovir Dose Optimization Post-Renal Transplant
M. Spinner,¹ V. Athans,¹ C. Koval.²
¹Dept. of Pharmacy, Cleveland Clinic, Cleveland, OH; ²Dept. of Infectious Diseases, Cleveland Clinic, Cleveland, OH.
Purpose: Renal function rapidly changes post-transplant requiring dose adjustment of CMV prophylaxis. We describe valganciclovir (VGCV) dosing accuracy in the outpatient setting and its associated…
2018 American Transplant Congress
Prevention of Hepatitis B Virus Reactivation in HBsAg-Positive Renal Transplant Recipients with Rituximab Treatment
J. Choi, J. Jung, H. Kwon, S. Shin, Y. Kim, D. Han.
Division of Kidney and Pancreas Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Background: The risk of Hepatitis B virus (HBV) reactivation under immunosuppressant has been well known. Hepatitis B virus reactivation increase patient mortality and graft failure…
2018 American Transplant Congress
The Impact of Immunosuppression on Mineral Metabolism One Year after Kidney Transplantation: Differences between a Mycophenolate-Based Regimen versus an mTOR-Inhibitor-Based One
D. Cucchiari,¹ S. Karam,² P. Ventura-Aguiar,¹ F. Diekmann,¹ J. Torregrosa.¹
¹Renal Transplant Unit, Hospital Clinic, Barcelona, Spain; ²Department of Medicine, Saint George Hospital University Medical Center, Beirut, Lebanon.
INTRODUCTION: after kidney transplantation, a substantial amount of patients still suffer from Mineral Bone Disorder. The role of different immunosuppressive therapies on mineral metabolism in…
2018 American Transplant Congress
Influence of mTOR Inhibitors on Metabolic Outcomes One Year after Kidney Transplantation: The Role of Pre-Transplantation Diabetes
D. Cucchiari,¹ S. Karam,² P. Ventura-Aguiar,¹ J. Torregrosa,¹ F. Diekmann.¹
¹Renal Transplant Unit, Hospital Clínic, Barcelona, Spain; ²Department of Medicine, Saint George Hospital, Beirut, Lebanon.
INTRODUCTION: mTOR inhibitors alter lipids and carbohydrate metabolism in kidney transplant recipients. Little is known if there is any difference between patients who were already…