Am J Transplant, Volume 18, Suppl 3 Archives - Page 104 of 211 - ATC Abstracts

2018 American Transplant Congress
Potential Impact of DCD Donor Recoveries on Heart Transplantation: Retrospective Analysis of a Limited UNOS Dataset
J. Lindower,² M. Farr,¹ S. Taylor,² U. Jorde,³ L. Chen,⁴ A. Gass,⁵ L. Truby,¹ S. Delair,² S. Pinney.⁶
¹New York Cardio-Thoracic Transplant Consortium, Troy, NY; ²Columbia/New York Presbyterian Hospital, New York; ³Montefiore Medical Center, Bronx, NY; ⁴Rochester University Medical Center, Rochester, NY; ⁵Westchester Medical Center, Valhalla, NY; ⁶Mount Sinai Medical Center, New York, NY.
Purpose: To review the volume and quality of potential DCD (Donation after Cardiac Death) Heart Transplant (HT) donors in the US, evaluate trends over time…
2018 American Transplant Congress
Evaluation of Drug Action on IgM Memory B Cell Survival and Growth In Vitro; -Application for Individualized Immunosuppression after Kidney Transplants-
Y. Matsuda,¹ K. Takahashi,¹ R. Imamura,² N. Nonomura,² Y. Yuzawa.¹
¹Nephrology, Fujita Health University, Toyoake, Aichi, Japan; ²Urology, Osaka University, Suita, Osaka, Japan.
(Background)Recently, the establishment of early diagnosis and treatment methods for antibody-mediated rejection (ABMR) has garnered much attention.Strong immunosuppression including desensitization is accompanied by severe side…
2018 American Transplant Congress
Factors Predicting Viability Achievement on Discarded Donor Livers Submitted to Extra-Corporeal Machine Perfusion
Y. Boteon,^1,2 R. Laing,^1,2 A. Schlegel,² J. Attard,^1,2 L. Wallace,¹ A. Smith,² T. Perera,² J. Isaac,² D. Mirza,² S. Afford,¹ H. Mergental.²
¹National Institute for Health Research, Birmingham Liver Biomedical Research Centre, University of Birmingham, Institute of Immunology and Immunotherapy, Birmingham, United Kingdom; ²Liver Unit, Queen Elizabeth Hospital, University Hospitals Birmingham, Birmingham, United Kingdom.
Background: Ex-vivo machine perfusion of livers (MP) may offer superior preservation for marginal donor organs. During normothermic machine perfusion (NMP) is possible to assess liver…
2018 American Transplant Congress
Comparison of Outcomes in African-American and White Primary Kidney Transplant Recipients: A Matched-Pair Analysis
F. Tedla, A. Brar, D. John, N. Sumrani, R. Gruessner, A. Gruessner, M. Salifu.
SUNY Downstate Medical Center, Brooklyn, NY.
Background: Racial differences in clinical and sociodemographic characteristics have been well recognized. This study aims to assess outcomes in African-American (AA) and white primary deceased…
2018 American Transplant Congress
Change in Estimated Glomerular Filtration Rate Pre and Post Development of Donor-Specific Antibodies after Kidney Transplantation
B. Ho,¹ S. Montag,^1,2 H. Bhagat,³ K. Atiemo,¹ A. Daud,¹ R. Kang,¹ L. Zhao,^1,2 J. Schwartz,³ D. Ladner.¹
¹Northwestern University Transplant and Outcomes Research Collaborative (NUTORC), Chicago; ²Dept of Preventive Medicine, Northwestern University, Chicago; ³Astellas Pharma Global Development, Inc., Northbrook.
Formation of de novo donor-specific antibodies (dnDSA) against human leukocyte antigens contributes to inferior kidney transplant (KT) outcomes. We assessed the effect of dnDSA on…
2018 American Transplant Congress
Characteristics and Outcomes of Kidney Transplant Recipients with More Than 25 Years of a Functioning Graft
S. Parajuli, D. Mandelbrot, F. Aziz, N. Garg, M. Mohamed, B. Muth, B. Astor, A. Djamali.
University of Wisconsin, Madison.
Background: There is limited information on clinical characteristics and outcomes of kidney transplant recipients (KTRs) with more than 25 years of graft survival.Methods: We addressed…
2018 American Transplant Congress
Successful Utilization of Deceased Donor Kidney Allografts with KDPI>85: The Organ is Not Wholly to Blame
A. Agarwal,¹ A. Nishio Lucar,² A. Nickkholgh,¹ K. Brayman,¹ A. Doyle,² J. Oberholzer.¹
¹Dept. of Surgery, University of Virginia Health System, Charlottesville, VA; ²Dept. of Internal Medicine, University of Virginia Health System, Charlottesville, VA.
Background: High kidney donor profile index (KDPI)>85% organs are increasingly discarded, suggesting missed opportunities to provide patients the benefits of transplantation. Herein, we report the…
2018 American Transplant Congress
Donor Acute Kidney Injury Does Not Affect Fibrosis on 1 Year Post-Transplant Kidney Biopsy
D. van der Windt, X. Chen, K. Lemon, C. Wu, N. Shah, R. Mehta, C. Puttarajappa, P. Sood, S. Hariharan, A. Ganoza, M. Wijkstrom, A. Humar, A. Tevar.
Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA.
PurposeThe use of kidneys from deceased donors with acute kidney injury (AKI) at the time of donation is a potential method by which to expand…
2018 American Transplant Congress
Impact of Direct Antiviral Therapy for Hepatitis C on Acute Rejection and DSA Formation in Kidney Transplant Recipients
Z. Zaky, S. Armanyous, L. Herlitz, E. Poggio, J. Augustine.
Cleveland Clinic, Cleveland, OH.
Background: Hepatitis C virus infection (HCV) has historically portended a poor outcome after kidney transplantation. With recent advent of direct antiviral agents (DAA), there has…
2018 American Transplant Congress
Use of Granulocyte Colony-Stimulating Factor for Leukopenia Post-Renal Transplant
S. Hamel,¹ V. Kuo,² D. Johnson,¹ R. Bloom,³ D. Sawinski,³ J. Trofe-Clark.^1,3
¹Pharmacy, Hosp of Univ. of Pennsylvania, Philadelphia; ²Pharmacy, Univ. of California San Francisco, San Francisco; ³Renal Division, Perelman School of Medicine, Univ. of Pennsylvania, Philadelphia.
Purpose: Leukopenia is a frequent complication in renal transplant recipients (RTRs). Granulocyte colony-stimulating factor (G-CSF) accelerates white blood cell (WBC) count recovery; but, published experience…