Am J Transplant, Volume 18, Suppl 3 Archives - Page 104 of 211 - ATC Abstracts

2018 American Transplant Congress
National Landscape of HIV+ Liver Transplant Candidates
A. Shaffer,¹ A. Thomas,¹ A. Massie,¹ S. Gustafson,² J. Snyder,² B. Shelton,³ R. Reed,³ J. Locke,³ D. Segev,¹ C. Durand.¹
¹JHU, Baltimore; ²SRTR, Minneapolis; ³UAB, Birmingham.
The annual number of HIV+ liver transplant (LT) recipients has increased >10-fold since 2002. However, candidate HIV-status is not collected by UNOS, and the national…
2018 American Transplant Congress
Characterization of Mycobacterium Tuberculosis Memory T Cell Subsets in Solid Organ Transplant Recipients with Previously Treated Active Tuberculosis
S. Nellimarla, Y. Natori, V. Ferreira, S. Husain, A. Humar, D. Kumar.
UHN, Toronto, Canada.
Introduction:Cell-mediated immune (CMI) responses including CD4+ and CD8+ T-cells contribute to control of Mycobacterium tuberculosis (MTb) infection. There are no data on long term TB-specific…
2018 American Transplant Congress
Infection Outcomes in Solid Organ Transplant Recipients Receiving Trimethoprim-Sulfamethoxazole as Opposed to Atovaquone for Prophylaxis
A. Drelick,¹ W. Mowrey,² G. Minamoto.³
¹Medicine, Division of Infectious Diseases, Weill Cornell Medical Center, New York, NY; ²Epidemiology & Population Health, Albert Einstein College of Medicine, Bronx, NY; ³Medicine, Division of Infectious Diseases, Montefiore Medical Center and the Albert Einstein College of Medicine, Bronx, NY.
Background: Pneumocystis jiroveci pneumonia (PJP) is an important illness amongst solid organ transplant (SOT) recipients. Trimethoprim-sulfamethoxazole (TMP-SMX) is the prophylaxis of choice based on efficacy…
2018 American Transplant Congress
Accommodation and Antibody Mediated Rejection Are Associated with Distinct TACI Polymorphisms in Kidney Transplant Recipients
M. Cascalho, M. Barbosa,¹ E. Farkash,² J. Platt.¹
¹Surgery, University of Michigan, Ann Arbor, MI; ²Pathology, University of Michigan, Ann Arbor, MI.
A. Trans-membrane Activator and CAML Interactor (TACI) gene is among the 5% most polymorphic genes in humans, TACI controls B cell differentiation and memory and…
2018 American Transplant Congress
Comparison of Temperatures for Optimal Preservation of Donor Kidneys during Oxygenated Pulsatile Perfusion
R. Bhattacharjee,¹ M. Richard-Mohamed,² A. Ruthirakanthan,³ R. Mayer,² S. Luke,³ H. Sharma,² M. TunAbraham,² B. Alharbi,² A. Haig,² P. Luke.^1,2,3
¹Matthew Mailing Centre for Translational Transplant Studies, London Health Sciences Centre, London, ON, Canada; ²Multi-Organ Transplant Program, London Health Sciences Centre, London, ON, Canada; ³Western University, Canada, London, ON, Canada.
Background. The current methods of preserving DCD renal allografts in either static cold solution or hypothermic pulsatile perfusion are unable to adequately protect the kidney…
2018 American Transplant Congress
The Superiority of Plasma Enriched Perfusate for Assessment of Donor Kidneys in an Ex-Vivo Normothermic Perfusion (EVNP) Setting
J. Palma, I. Palma, Y. Smolin, A. Perry, J. Sageshima, R. Perez.
Surgery, Transplant Division, UC Davis Health System, Sacramento, CA.
EVNP has been used to assess and repair marginal organs prior to transplantation but the optimal perfusate composition is unknown. We hypothesize that EVNP with…
2018 American Transplant Congress
Consistency of DCD Procurement Procedures across Organ Procurement Organizations – Preliminary Findings
G. Mitro,¹ A. Ortiz,² R. Warnock,³ P. Wiederhold,³ K. Jiles,³ J. Ortiz.¹
¹University of Toledo College of Medicine, Toledo, OH; ²University of California Los Angeles, Los Angeles; ³Life Connection of Ohio, Toledo, OH.
Intro: Variation among procedures across Organ Procurement Organizations (OPOs) may account for discrepancies in outcomes associated with the use of deceased after cardiac death (DCD).…
2018 American Transplant Congress
Cognitive Impairment and Graft Loss in Kidney Transplant Recipients
A. Thomas,¹ J. Ruck,¹ A. Shaffer,¹ C. Haugen,¹ H. Ying,¹ F. Warsame,¹ N. Chu,¹ M. Carlson,¹ A. Gross,¹ S. Norman,² D. Segev,¹ M. McAdams-DeMarco.¹
¹JHU, Baltimore; ²University of Michigan, Ann Arbor.
Cognitive impairment is common in end-stage renal disease patients and impedes adherence to complex treatment regimens. Given the complexities of post-transplant immunosuppression, we hypothesized that…
2018 American Transplant Congress
Urinary Sulfate Excretion and Late Graft Failure in Renal Transplant Recipients
M. Said,¹ A. Post,¹ I. Minovic,¹ M. van Londen,¹ H. van Goor,² D. Postmus,³ M. Heiner-Fokkema,⁴ E. van den Berg,¹ A. Pasch,⁵ G. Navis,¹ S. Bakker.¹
¹Department of Internal Medicine, University Medical Center Groningen, Groningen, Netherlands; ²Department of Pathology and Medical Biology, University Medical Center Groningen, Groningen, Netherlands; ³Department of Epidemiology, University of Groningen, Groningen, Netherlands; ⁴Department of Laboratory Medicine, University Medical Center Groningen, Groningen, Netherlands; ⁵Department of Biomedical Research, University of Bern, Bern, Switzerland.
BackgroundHydrogen sulfide (H2S), produced from the metabolism of dietary sulfur-containing amino acids, is allegedly a potential renoprotective compound. High 24h urinary excretion of pathway intermediate…
2018 American Transplant Congress
Histogenomics: Molecular Profiling of Kidney Biopsies Predict Delayed Graft Function
P. Rao,¹ D. Deo,¹ B. Fyfe-Kirschner,² R. Siderits.²
¹NJ Sharing Network, New Providence, NJ; ²Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ.
IntroductionHistologic assessments of donor renal biopsies for percentage global glomerulosclerosis, interstitial fibrosis and arterial sclerosis can predict renal graft failure post-transplant.The morphologic evaluation of renal…