Am J Transplant, Volume 17, Suppl 3 Archives - Page 95 of 181 - ATC Abstracts

2017 American Transplant Congress
Inflammatory Conditions Dictate the Effect of MSC on B Cell Function.
F. Luk,¹ L. Carreras-Planella,² S. Korevaar,¹ S. de Witte,¹ F. Borràs,² M. Betjes,¹ C. Baan,¹ M. Hoogduijn,¹ M. Franquesa.^1,2
¹Nephrology and Transplantation, Dept. of Internal Medicine, Erasmus MC, University Medical Center, Rotterdam, Netherlands; ²Nephrology and Transplantation, Institut d'Investigació Germans Trias i Pujol, Badalona, Spain
The immunomodulatory capacity of mesenchymal stem or stromal cells (MSC) makes them a promising therapeutic tool for immune disease and organ transplantation. The effects of…
2017 American Transplant Congress
Avoidance or Reduction of Rituximab Might Improve Clinical Outcomes in ABO-Incompatible Renal Transplantation: Advantages and Disadvantages of Rituximab.
M. Okada,¹ Y. Watarai,¹ K. Iwasaki,² K. Murotani,³ T. Hiramitsu,¹ M. Tsujita,¹ N. Goto,¹ S. Narumi,¹ T. Kobayashi.²
¹Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan; ²Renal Transplant Surgery, Aichi Medical University, Nagakute, Japan; ³Clinical Research Center, Aichi Medical University, Nagakute, Japan
BACKGROUNDPretransplant desensitization with rituximab has contributed to drastic improvements in ABO-incompatible renal transplantation (ABO-I). However, ABO-I outcomes are still worse than those of ABO-identical or…
2017 American Transplant Congress
Recurrent HCC After Radiofrequency Ablation or Liver Resection Can Be Effectively Treated with Salvage Transplantation.
H. Muaddi,¹ D. Al-Adra,¹ J. Shaw,¹ D. Grant,¹ P. Greig,¹ I. McGilvray,¹ M. Cattral,¹ A. Wei,¹ C.-A. Moulton,¹ J. Kachura,² R. Beecroft,² M. Selzner,¹ A. Ghanekar,¹ S. Gallinger,¹ S. Cleary,¹ G. Sapisochin.¹
¹General Surgery, University of Toronto, Toronto, ON, Canada; ²Medical Imaging, University of Toronto, Toronto, ON, Canada
Background:Liver resection (LR) and radiofrequency ablation (RFA) represent curative therapies for early stages of hepatocellular carcinoma (HCC). If tumour recurrence occurs, salvage liver transplant (SLT)…
2017 American Transplant Congress
Variations in Risk-Appetite Between UK Kidney Transplant Centres and Impact on Patient and Graft Outcomes.
P. Trotter,^1,2 M. Robb,² D. Summers,^1,2 J. Bradley,¹ J. Neuberger,^2,4 C. Callaghan.^2,3
¹Department of Surgery, University of Cambridge, Cambridge, United Kingdom; ²Organ Donation and Transplantation, NHS Blood and Transplant, Bristol, United Kingdom; ³Transplant Unit, Guys and St Thomas' NHS Foundation Trust, London, United Kingdom; ⁴Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom
Introduction: Risks associated with deceased donors may be donor-related, organ-related, or both. Variations between transplant centres in the risks they are prepared to accept ('risk…
2017 American Transplant Congress
Successful Utilization of Deceased Donor Kidney Allografts with KDPI>85: A Single Center Experience.
A. Agarwal, W. Ally, K. Brayman.
University of Virginia, Charlottesville, VA
In December 2014, UNOS implemented broad changes in the new Kidney Allocation System (KAS). Recent UNOS summary reports suggest that nationally, organ discard rates have…
2017 American Transplant Congress
MicroRNAs Differentiate Between Antibody and T-Cell Mediated Renal Allograft Rejection.
T. van den Bosch,¹ M. Clahsen-van Groningen,² F. Rezaee,³ D. Nieboer,⁴ E. Steyerberg,⁴ C. Baan,¹ A. Rowshani.¹
¹Internal Medicine, Section of Nephrology and Transplantation, Erasmus University Medical Center, Rotterdam, Netherlands; ²Pathology, Erasmus University Medical Center, Rotterdam, Netherlands; ³Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands; ⁴Public Health, Erasmus University Medical Center, Rotterdam, Netherlands
Purpose: MicroRNAs are important immune regulators of gene and protein expression. Both circulating and intragraft expression of microRNAs have been related to renal allograft rejection.…
2017 American Transplant Congress
Medicinal Herb Cordyceps Sinensis Promotes Long-Term Allograft Survival by Tipping the Balance Between CD4+FoxP3+ Tregs and CD8+ Tcm Cells.
Z. Dai,¹ H. Dai.²
¹Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou, China; ²University of Pittsburgh, Pittsburgh, PA
Achieving long-term allograft survival or tolerance without continuously global immunosuppression is highly desirable in transplantation. This study was set to induce long-term allograft survival using…
2017 American Transplant Congress
Hypoxia Induces Tissue Factor Upregulation in Isolated Human Islets.
B. Sandhu,¹ M. Prendecki,¹ G. Rutter,¹ A. Martinez-Sanchez,¹ N. Kanda,¹ N. Galloway-Phillips,¹ R. Smith,² C. Pusey,¹ V. Papalois.¹
¹Imperial College, London, United Kingdom; ²King's College, London, United Kingdom
Purpose: Early islet loss post-infusion remains a significant problem in islet transplantation, despite the use of heparinised media to abrogate the effects of Tissue Factor…
2017 American Transplant Congress
Protective Effect of Crepidiastrum denticulatum Extract Pretreatment Against Hepatic Ischemia-Reperfusion Injury in Mice.
H. Jang, H. Lee, C. Park, D. Eom, J. Lee, M. Oh, J. Yoo, C. Rho.
Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Anesthesia, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Pathology, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Natural Medicine Center, Korea Institute of Science and Technology, Gangneung, Gangwon, Korea; Natural Medicine Center, Korea Institute of Science and Technology, Gangneung, Gangwon, Korea
Crepidiastrum denticulatum (CD) is a well-known, traditionally consumed vegetable in Korea, which was recently reported to have bioactive compounds with detoxification and antioxidant properties. Ischemia-reperfusion…
2017 American Transplant Congress
Bacteremia in Kidney Transplant Recipients: Incidence, Risk Factors, and Outcomes.
S. Brar, Y. Wang, A. Cannitelli, Y. Li, O. Famure, S. Husain, J. Kim.
Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada
Background: Bloodstream infections or bacteremia is a serious complication after kidney transplantation. The incidence, risk factors, and outcomes of bacteremia among kidney transplant recipients have…