ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Single Nuclear Polymorphisms of Complement Component 4 and Component 5 in Renal Transplant Recipients with Antibody-Mediated Rejection.

    Z. Wang, Z. Han, J. Tao, R. Tan, M. Gu.

    Urology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China

    Background: Antibody-mediated rejection (ABMR) is an important cause of allograft dysfunction in short-term and long-term period. The complement component 4 (C4) and component 5 (C5)…
  • 2017 American Transplant Congress

    The Role of Toll-Like Receptor 4 in Islet Transplantation and a Novel Method of Protection Using Chemical Surface Modification.

    C. Chang,1 G. Yoshimatsu,2 B. Akinbobuyi,4 M. Lawrence,2 R. Kane,1 B. Naziruddin.3

    1Institute of Biomedical Studies, Baylor University, Waco, TX; 2Baylor Scott and White Research Institute, Dallas, TX; 3Baylor Simmons Transplant Institute, Dallas, TX; 4Department of Chemistry and Biochemistry, Baylor University, Waco, TX

    Toll-like Receptor 4 (TLR4) is the canonical receptor for lipopolysaccharide (LPS), however recent evidence reveals that TLR4 also plays an important role in ischemia-reperfusion injury…
  • 2017 American Transplant Congress

    Percentage of CD19+ B Cells as a Predictor of Acute Antibody-Mediated Rejection After Administration of Rituximab in ABO-Incompatible Kidney Transplantation.

    T. Hirose, D. Iwami, K. Hotta, H. Sasaki, H. Higuchi, N. Shinohara.

    Urology, Hokkaido University, Sapporo, Japan

    [Introduction] Administration of rituximab to ABO-incompatible kidney transplant (ABOi-KTx) recipients is recognized as effective and safe. A single dose of 375 mg/m2 rituximab is generally…
  • 2017 American Transplant Congress

    Prognostic Significance of Preoperative Neutrophil-Lymphocyte Ratio in Patients Undergoing Liver Transplantation with Hepatocellular Carcinoma within Milan Criteria.

    S.-K. Kwon,1 J. Lee,1 S. Song,1 J. Lee,1 D. Kim,1 J. Lee,2 M. Kim,1 G. Choi,1 J. Choi,1 D. Han,1 S. Kim,1 D. Joo.1

    1Department of Surgery, Yonsei University College of Medicine, Seoul, Korea; 2Department of Surgery, CHA University, Bundang, Korea

    Introduction: The systemic inflammation biomarker, neutrophil-to-lymphocyte ratio (NLR) has been reported to be a predioctor of poor survival in patients with various cancers. The purpose…
  • 2017 American Transplant Congress

    Comparison of Long-Term Survival Outcome Between Primary Liver Transplantation and Hepatic Resection with Consequent Salvage Transplantation for Hepatocellular Carcinoma within Milan Criteria – A Single-Center Experience.

    K. Ng,1 K. Chok,1 A. Chan,1 T. Wong,1 J. Fung,2 C.-M. Lo.1

    1Department of Surgery, The University of Hong Kong, Hong Kong, Hong Kong; 2Department of Medicine, The University of Hong Kong, Hong Kong, Hong Kong

    Background: Whether primary liver transplantation (PLT) is superior to the upfront hepatic resection (HR) and salvage liver transplantation (SLT) for hepatocellular carcinoma (HCC) within Milan…
  • 2017 American Transplant Congress

    Donor/Recipient Matching Using the Creatinine Clearance Match Ratio (CCMR) Is Superior to the Kidney Donor Profile Index (KDPI) Predicting Early but Not Late Outcomes for Deceased Donor Kidney Transplantation.

    J. Halldorson, N. Karimi.

    Transplant Surgery, University of California, San Diego, CA; Surgery, Royal College of Surgeons, Dublin, Ireland

    A Creatinine Clearance based Donor/Recipient matching strategy (CCMR) was developed to better optimize metabolic demand of the recipient with donor kidney function. Prior work in…
  • 2017 American Transplant Congress

    Estimating Donor Organ Quality with Baseline Histology and Kidney Donor Risk Index for Predicting Graft Outcomes in Deceased Donor Kidney Transplantation.

    K. Park,1 S. Park,2 H. Park,2 J. Park,1 H. Chung,1 M. Kim,3 H. Cho,2 J. Lee.1

    1Internal Medicine, Ulsan University Hospital, Ulsan, Republic of Korea; 2Surgery, Ulsan University Hospital, Ulsan, Republic of Korea; 3Pathology, Ulsan University Hospital, Ulsan, Republic of Korea

    Background: Donor organ quality is a key determinant of graft outcomes in deceased donor kidney transplantation (DDKT). The effect of baseline histology at the time…
  • 2017 American Transplant Congress

    Identification of Novel Diagnostic Biomarkers in Liver Transplantation Tolerance.

    G.-Q. Shen,1 M. Morita,1 C. Miller,1 K. Hashimoto,1 L. Lu,1 S. Qian,1 J. Fung.2

    1Cleveland Clinic, Cleveland; 2University of Chicago, Chicago

    Current success in liver transplantation (LTX) relies on life-time administration of non-specific immunosuppressive drugs, leaving patients prone to infection and cancer. Previous reports indicated about…
  • 2017 American Transplant Congress

    D-Dimer Level, in Association with Humoral Responses, Negatively Correlates with Survival of Porcine Islet Grafts in Nonhuman Primates with Immunosuppression.

    H. Kang,1 H. Lee,1 E. Park,1 J. Kim,2 B. Min,2 C.-G. Park.2

    1Laboratory Medicine, Hallym University College of Medicine, Anyang, Korea; 2Xenotransplantation Research Center, Seoul National University College of Medicine, Seoul, Korea

    Background: Several immunosuppression (IS) regimens achieve long-term graft survival in nonhuman primates (NHPs) after porcine islet transplantation (PITx), but their success rates vary. To understand…
  • 2017 American Transplant Congress

    Role of Protease Activated Receptor 1 and Sphingosine-1-Phospate Receptor 1 in Mice Hepatic Ischemia-Reperfusion Injury for Targeting Cell Signal Pathways of Activated Protein C.

    T. Ito, N. Kuriyama, H. Kato, Y. Iizawa, A. Tanemura, Y. Murata, Y. Azumi, M. Kishiwada, S. Mizuno, M. Usui, H. Sakurai, S. Isaji.

    Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Japan

    Introduction: Hepatic ischemia-reperfusion injury (IRI) is a serious comlication during liver surgery. As for therapeutic strategies on hepatic IRI, we previously demonstrated that activated protein…
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