2017 American Transplant Congress
A Combination of Anti-CD40L-Ab, Rapamycin, and Donor Apoptotic Cells Prolongs Allogeneic Pancreatic Islet Survival in Sensitized Mice by Regulating Memory Responses.
Accelerated rejection of allografts has been a clinical challenge in solid organ transplantation particularly in sensitized recipients with donor-specific antibodies (DSA) and memory cell repertoires.…2017 American Transplant Congress
Impact of a B-Cell Targeting Agent on Antibody Mediated Rejection and Graft' Survival in Liver Transplantation with Preformed DSAs.
Introduction The negative impact of preformed anti-HLA donor specific antibodies (DSAs) in liver transplantation is clearly established. However, the potential interest of a B-cell depleting…2017 American Transplant Congress
Myeloid HO-1 Orchestrates Liver Graft Function via SIRT1/p53 Signaling: From Mouse-to-Human.
Background/Aim: Although the efficacy of heme oxygenase-1 (HO-1) to combat liver ischemia-reperfusion injury (IRI) in animal models is well-established, cell-specific HO-1 function and mechanisms of…2017 American Transplant Congress
Efficacy and Safety of Everolimus with Reduced-Exposure Tacrolimus and Corticosteroid Withdrawal in De Novo Pediatric Renal Transplant Recipients: 12-Month Results from the CRADLE Study.
PURPOSE: We present 12-month (M) results from the CRADLE study (NCT01544491) that assessed efficacy and safety of everolimus (EVR) with reduced-exposure tacrolimus (rTAC) and early…2017 American Transplant Congress
Risk Factors of Treatment Failure in Antibody Mediated Rejection.
Background: Antibody-mediated rejection (AMR) is recognized as the major cause of kidney allograft loss. Despite an aggressive treatment, prognosis is usually poor. The aim of…2017 American Transplant Congress
DSA Presence Does Not Affect Renal Histology and Clinical Outcome in Chronic Active Antibody Mediated Rejection.
1Erasmus MC, Rotterdam, Netherlands; 2Leiden UMC, Leiden, Netherlands
Introduction. Chronic active antibody mediated rejection (caABMR) is a major cause of long term renal allograft dysfunction. It is defined by the presence of microvascular…2017 American Transplant Congress
Donor Lymphoid Chimerism in Early Recognition and Prediction of Clinical Outcome Caused by Acute Graft versus Host Disease After Solid Organ Transplant.
Introduction: Acute graft versus host disease (aGvHD) after solid organ transplant (SOT) is rare but related with high mortality. Early accurate diagnosis is critical for…2017 American Transplant Congress
Three Year Outcomes Following Positive Crossmatch Renal Transplantation Despite Failure to Convert to Negative Flow Crossmatch After Desensitization.
Purpose: To determine outcomes of positive crossmatch (PXM) renal transplant recipients that failed to convert to a negative flow cytometry crossmatch (FCXM) despite desensitization. Methods:…2017 American Transplant Congress
Different Prognostic Factors for Early and Late Recurrence After Adult Living Donor Liver Transplantation for Hepatocellular Carcinoma.
Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea
Recurrence after liver transplantation (LT) for hepatocellular carcinoma (HCC) remains unsatisfactory. However, some patients with HCC recurrence after LT show good long-term survival results. The…2017 American Transplant Congress
Expanded Criteria for HCC in Liver Transplantation.
Introduction: Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and the third highest cause of death related to malignancy. Since HCC diagnosis is…
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