ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Predictive Value of Renal Poly (ADP-Ribose) Polymerase (PARP) Expression Both in Inflammation and Interstitial Fibrosis Processes in Recipients with Antibody-Mediated Rejection.

    B. Ozdemir,1 F. Ozdemir,2 E. Baskin,2 M. Haberal.3

    1Pathology, Baskent University, Ankara, Turkey; 2Nephrology, Baskent University, Ankara, Turkey; 3Transplant Surgery, Baskent University, Ankara, Turkey

    The activation of PARP is well considered to play an augmenting role in inflammation. However, its role in the development of fibrosis is not well…
  • 2017 American Transplant Congress

    Inferior 10-Year Graft and Patient Survival After End-to-Side Reconstruction for Two Renal Arteries in Living Donor Renal Transplantation.

    S. Yamanaga,1,2,3 A. Posselt,1 C. Freise,1 C. Niemann,1 A. Rosario,1 D. Fernandez,1 T. Kobayashi,3 A. Ahearn,4 M. Tavakol,1 S.-M. Kang.1

    1Department of Surgery, UCSF, San Francisco, CA; 2Department of General Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan; 3Department of Renal Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan; 4Department of Transplant Surgery, UMass Memorial Medical Center, Worcester, MA

    Purpose: Living donor kidneys with two arteries can be revascularized using various techniques depending on anatomy and surgeon preference. We hypothesized that the revascularization technique…
  • 2017 American Transplant Congress

    Potential Living Kidney Donors (LKD) Concerns About Opting Out and Preferences for an 'Alibi'.

    K. Yu,1 C. Thiessen,1 S. Li,1 D. Dobosz,1 J. Gannon,1 K. Kennedy,2 D. Gray,3 A. Mussell,3 P. Reese,3 S. Kulkarni,1 E. Gordon.2

    1Yale U, New Haven; 2Northwestern U, Chicago; 3U Pennyslvania, Philadelphia

    PurposeTo evaluate potential LKDs comfort discussing opting out with their intended recipient (IR) and preferences for alibisMethodsWe conducted a prospective, longitudinal study of potential LKDs…
  • 2017 American Transplant Congress

    Impact of Dialysis During the Transplant Admission on Transplant and Post-Transplant Cost of Care.

    J. Tao,1 C. Horstman,1 W. Bannister,1 M. Schnitzler,2 F. Irwin,1 A. Bonagura,1 B. Laihinen.1

    1Complex Medical Conditions, Optum, UnitedHealth Group, Eden Prairie, MN; 2Surgery, St Louis University, St Louis, MO

    This study examines the impact of dialysis during the transplant admission on total cost of transplant and one year post-transplant care for kidney, liver, and…
  • 2017 American Transplant Congress

    Biological Interplay Between Circulating HLA-sp Alloreactive Memory B-Cells and Long-Lived Plasma Cells in Kidney Transplant Patients Undergoing Chronic ABMR.

    S. Luque,2 M. Lúcia,4 M. Jarque,2 E. Crespo,2 E. Melilli,1 J. Martorell,3 J. Cruzado,1,2 J. Torras,1,2 J. Grinyó,1,2 O. Bestard.1,2

    1Kidney Transplant Unit, Bellvitge University Hospital, Barcelona, Spain; 2Experimental Nephrology Laboratory, IDIBELL, Barcelona, Spain; 3Immunogenetics Laboratory, Hospital Clínic, Barcelona, Spain; 4Transplant Immunology, School of Medicine, Stanford

    Alloreactive humoral responses are one of the main causes of immune-mediated allograft injury in kidney transplantation. Different biological compartments are involved in the generation and…
  • 2017 American Transplant Congress

    Sirolimus Prolonged Survival After Living Donor Liver Transplantation for HCC Beynd Milan Criteria; Outcome of a Multicenter Prospective Randomized Phase II Trial (ClinicalTrials.gov Identifier: NCT01374750).

    K.-W. Lee,1 S.-H. Kim,2 N.-J. Yi,1 S.-K. Hong,1 G. Yoon,1 H. Kim,1 D. Oh,1 S.-S. Han,2 S.-J. Park,2 K.-S. Suh.1

    1Department of Surgery, Seoul National University, Seoul, Republic of Korea; 2Center for Liver Cancer, National Cancer Center, Goyangsi, Republic of Korea

    Background:It is unclear whether the reported benefit of mTORi in LT for HCC is from direct effect of mTOR inhibitors. We aimed to compare directly…
  • 2017 American Transplant Congress

    Autophagy Regulates LG3 Maturation and Export in Apoptotic Exosome-Like Vesicles.

    D. Beillevaire,1,2,4 M. Francis,1,2,4 G. Diane,2 B. Éric,3,4 D. Mélanie,1,2,4 H. Marie-Josée.1,2,4

    1CRCHUM, Montréal, Canada; 2Université de Montréal, Montréal, Canada; 3CHUL, Québec, Canada; 4CNTRP, Edmonton, Canada

    Background: Autoantibodies to apoptotic antigens such as LG3 – a C-terminal fragment of perlecan– are present pre-transplantation and contribute to organ rejection in renal transplant…
  • 2017 American Transplant Congress

    Post-Donation Remaining Donor Kidney Function as Measured by CKD-EPI Formula at 2 Years Correlates and Is Predicted by Remaining Donor Kidney Volume.

    S. Hussain, A. Diez, A. Khalil, M. Yaqub, D. Mishear, T. Taber, O. Adebiyi, C. Sundaram, W. Goggins, J. Powelson, A. Sharfuddin.

    Indiana University School of Medicine, Indianapolis

    Aim: The aim of our study was to evaluate whether preserved kidney volume correlates with and can predict donor renal function at 2-years post-donation using…
  • 2017 American Transplant Congress

    De Novo Use of Everolimus Reduces Late-Onset Cytomegalovirus Primary Disease Occurring After Antiviral Prophylaxis Discontinuation in Kidney Transplant Recipients.

    A. Devresse,1 V. Avettand-Fenoel,2 A. Scemla,3 L. Morin,3 X. Lebreton,3 C. Tinel,3 L. Amrouche,3 L. Lamhaut,4 M.-O. Timsit,5 J. Zuber,3 C. Legendre,3 D. Anglicheau.3

    1Nephrology Unit, Cliniques Universitaires Saint-Luc, Brussels, Belgium; 2Virology Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France; 3Kidney Transplantation and Intensive Care Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France; 4Anesthesia Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France; 5Urology Unit, Hôpital Necker-Enfants Malades, AP-HP, Paris, France

    Background: Donor (D)+/recipient (R)- serostatus is critically associated with an higher risk of cytomegalovirus (CMV) infection and disease. Antiviral prophylaxis is conventionally used in such…
  • 2017 American Transplant Congress

    The Impact of Social Support on Kidney Transplant Listing Decisions: Results from a Discrete Choice Experiment.

    K. Ladin,1,2 J. Emerson,2 Z. Butt, E. Gordon, D. Hanto, T. Lavelle.2

    1Occupational Therapy, Tufts University, Medford, MA; 2Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA

    Background: Although the Centers for Medicare and Medicaid Services require that social support be used to determine transplant eligibility, guidance is vague and centers vary…
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