ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Usefulness of Multi-Detector Computed Tomography (MDCT) Scanning as a Replacement for Diethylenetriamine Pentaacetic Acid (DTPA).

    H. Lee,1 W. Han,1 K. Huh,2 M. Kim,2 S. Kim,2 Y. Kim,2 Y. Yoon.1

    1Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Transplantation Surgery, Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea

    Objective: Diethylenetriamine pentaacetic acid (DTPA) and multi-detector computed tomography (MDCT) can predict postoperative estimated glomerular filtration rate (eGFR) in a live kidney donor. Accordingly, we…
  • 2017 American Transplant Congress

    Seasonality of Mortality and Graft Failure Among Kidney Transplant Recipients in the US.

    B. Astor,1 M. Melamed,2 D. Mandelbrot,1 A. Djamali.1

    1University of Wisconsin School of Medicine and Public Health, Madison, WI; 2Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY

    The incidence of mortality in the general population is significantly higher in winter than in summer. It is unknown whether such a seasonal difference exists…
  • 2017 American Transplant Congress

    State Law Restrictions on HIV Positive-to-Positive Transplantation.

    S. Rasmussen,1 A. Glazier,2 A. Cash,1 M. Henderson,1 B. Boyarsky,1 K. Miller,3 S. Schoettes,4 D. Segev,1 C. Durand.1

    1JHU, Baltimore; 2NEOB, Waltham; 3HIV Medicine Association, Arlington; 4Lambda Legal, Chicago

    Background In 1984 the National Organ Transplant Act banned the recovery of organs from HIV-positive (HIV+) individuals. In 2013 the HIV Organ Policy Equity (HOPE)…
  • 2017 American Transplant Congress

    Willingness of Canadian ESRD Patients to Consider Transplant Tourism.

    J. Gill, G. Gill, Y. Joffres, C. Rose, J. Gill, L. Russell, A. Levin, C. Richardson.

    UBC, Vancouver, Canada

    BackgroundTransplant tourism refers to travel for transplantation involving organ trafficking or transplant commercialism, and is associated with poor outcomes. While some characteristics of transplant tourists…
  • 2017 American Transplant Congress

    Uptake of Extracellular Mitochondria Activates Human Endothelial Cells That Stimulate Alloreactive Effector T Cell Responses.

    T. Brennan,1 F. Feng,1 L. Lin,1 M. Song,1 Q.-J. Li,2 A. Kirk,1,2 H. Xu.1

    1Surgery, Duke University, Durham, NC; 2Immunology, Duke University, Durham, NC

    Introduction: Vascular endothelial cells (VECs), the initial barrier between host immunity and donor allograft tissue, play a critical role in allograft rejection. We investigated the…
  • 2017 American Transplant Congress

    Current Treatments for Small Hepatocellular Carcinoma: A Network Meta-Analysis of Randomized Controlled Trials.

    Z. Guo, Z. Zheng, X. He, G. Chen.

    The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Purpose: Numerous randomized controlled trials (RCTs) concerning treatments for small hepatocellular carcinoma (HCC) have been reported. Herein, we conducted a network meta-analysis integrating current evidence…
  • 2017 American Transplant Congress

    Precise Antibody Characterization Using Multiple Solid Phase Assay Platforms Is Critical for Accurate Virtual Crossmatching.

    D. Li,1 O. Timofeeva,1 M. Awwad,1 C. Cody,2 S. Najjar,2 S. Rosen-Bronson.1

    1Histocompatibility Laboratory, MedStar Georgetown University Hospital, Washington, DC; 2MedStar Heart Institute, Washington Hospital Center, Washington, DC

    Purpose: Virtual crossmatch (VXM) has been utilized in heart transplant (txp) for more than a decade. Many labs base the VXM solely on single antigen…
  • 2017 American Transplant Congress

    Graft Survival in De Novo Donor-Specific Antibodies and Positive Flow Crossmatch Kidney Transplants Is influenced by Class I and Class II.

    S. Montag,1,2 B. Ho,1 H. Bhagat,3 E. Lee,3,4 K. Atiemo,1 A. Daud,1 R. Kang,1 L. Zhao,1,2 J. Schwartz,3 D. Ladner.1

    1Northwestern University Transplant and Outcomes Research Collaborative (NUTORC), Chicago; 2Dept of Preventive Medicine, Northwestern University, Chicago; 3Astellas Pharma Global Development, Northbrook; 4Now with UCB, Atlanta

    Patients with de novo donor-specific antibodies (dnDSA) show inferior graft survival in numerous small studies. We assessed the effect of dnDSA on graft and patient…
  • 2017 American Transplant Congress

    Infusion of Polyclonal Tregs Modulates Subclinical Kidney Transplant Inflammation: Final Report of TASK Pilot Trial.

    S. Chandran, Q. Tang, M. Sarwal, Z. Laszik, A. Putnam, T. Sigdel, E. Tavares, J. Bluestone, F. Vincenti.

    UCSF, San Francisco

    Purpose:Treg therapy can reverse established inflammation in animal models. We conducted a pilot safety & feasibility trial of Treg therapy for subclinical kidney transplant inflammation.Methods:Peripheral…
  • 2017 American Transplant Congress

    Pre-Transplant Circulating TNFR2+ Regulatory T Cells Predict Acute Rejection within the First 6 Months After Kidney Transplantation.

    M.-T. Nguyen,1 S. Sahakian,2 S. Liu,2 Y. Wang,2 J. Tchervenkov,2 S. Paraskevas.2

    1Department of Surgery, Columbia University, New York, NY; 2Department of Surgery, McGill University, Montreal, QC, Canada

    Background: Acute rejection (AR) mostly occurs during the first 6 months after kidney transplantation and contributes importantly to graft loss. Diagnosis relies on changes in…
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