2017 American Transplant Congress
Anti-Angiotensin Type 1 Receptor Antibodies Associate with Rejection in Simultaneous Pancreas and Kidney Transplant and Pancreas Transplant Alone Recipients.
Comprehensive Transplant Center, Cedars Sinai Medical Center, Los Angeles, CA
Background: Anti-angiotensin type 1 receptor antibodies (AT1R Ab) have been found to have a strong association with antibody mediated rejection (Reinsmoen et al, Transpl 2010;…2017 American Transplant Congress
TFR:TFH Cell Ratio Correlates with Anti-Donor Germinal Center Reactivity and Donor-Specific Antibody Formation Following Transplantation.
Emory Transplant Center, Emory University School of Medicine, Atlanta, GA
Kidney transplantation is the treatment of choice for patients with end-stage renal disease. Although short-term outcomes are excellent, long-term allograft survival rates remain inadequate. It…2017 American Transplant Congress
Mouse FCs May Contain Lymphoid Progenitor Cells That Have the Capacity to Generate B and T Cells In Vivo.
Institute for Cellular Therapeutics, University of Louisville, Louisville, KY
CD8+/TCR- facilitating cells (FCs) are a rare bone marrow-derived cell population that enhances engraftment of hematopoietic stem cells (HSC) in major histocompatibility complex disparate recipients…2017 American Transplant Congress
Primary Graft Dysfunction After Pediatric Heart Transplant.
Pediatric Cardiology, Washington University School of Medicine, St. Louis, MO
Background: Primary graft dysfunction (PGD), as defined by ISHLT Consensus Guidelines, has been associated with worse outcomes in adult heart transplant recipients, even in patients…2017 American Transplant Congress
Emergency Department Utilization Among Kidney Transplant Recipients in the United States.
Background:Single center studies suggest that kidney transplant (KTx) recipients have a high rate of emergency department (ED) utilization, and ED visits are associated with graft…2017 American Transplant Congress
APOL1 Genotype Does Not Affect Donor Renal Function Post Live Kidney Donation.
Background: Apolipoprotein-L1 (APOL1) risk variants have emerged as a predictor of renal disease in individuals of African Ancestry (AA). The effect of APOL1 risk variants…2017 American Transplant Congress
Differential Expression of Long Noncoding RNAs During Cardiac Allograft Rejection.
While transplant rejection is the major restriction in successful long lasting graft survival, induction of sustainable immune tolerance against transplant is one of the major…2017 American Transplant Congress
We Wish This Would Never Happen Again! Implementation of an Adverse Event Review System to Improve the Safety of Pediatric Solid Organ Transplant (SOT) Patients.
Background: 50% of SOT centers are cited by CMS for inadequate review of adverse events (AE)s. AE reviews are inconsistently performed, rarely cover near misses…2017 American Transplant Congress
Strategy for Analysis of Donor-Specific Antibody Repertoire: Paired Immunoglobulin Heavy and Light Chain Analysis of Individual Memory B Cells.
Antibody-mediated rejection (ABMR) is the most challenging immunological barrier to overcome in human transplantation and one of the most prevalent causes of kidney allograft loss.…2017 American Transplant Congress
Training for Transplant: Frailty Assessment and Optimization in Kidney Transplant Candidates.
Surgery, Scott & White Medical Center, Temple, TX
Purpose: To design and implement a frailty assessment and optimization program addressing potential modifiable risk factors that would ordinarily disqualify patients from kidney and/or pancreas…
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