ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Once-Daily versus Twice-Daily Tacrolimus in Living Kidney Transplantation: A Multicenter, Parallel Group, Open-Label, 5-Year, Randomized Non-Inferiority Trial.

    K. Unagami,1 M. Okumi,2 T. Hirai,2 D. Toki,3 H. Shirakawa,4 T. Shimizu,2 K. Omoto,5 M. Inui,3 H. Ishida,2 K. Nitta,1 K. Tanabe.2

    1Nephrology, Tokyo Women's Medical University, Tokyo, Japan; 2Urology, Tokyo Women's Medical University, Tokyo, Japan; 3Urology, Tokyo Women's Medical University Yachiyo Medical Center, Yachiyo, Japan; 4Urology, Ohkubo Hospital, Tokyo, Japan; 5Transplant Surgery, Toda Chuo General Hospital, Toda, Japan

    Background:Tacrolimus (TAC)-based induction therapy appears to be the standard immunosuppressive regimen for most kidney transplantation recipients (KTRs). TAC is available as a twice-daily (TAC-BID) and…
  • 2017 American Transplant Congress

    Efficacy of Calcineurin Inhibitors Transferring to Rapamycin in Live Kidney Transplantation from Old Donors to Young Recipients.

    G. Chen, C. Wang, Z. Wu, C. Wang, J. Qiu, L. Chen.

    Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    Background Calcineurin inhibitor(CNI) nephrotoxicity is one of the major reasons for chronic allograft injury in live kidney transplantation from old donors to young recipients. Therefore…
  • 2017 American Transplant Congress

    Tacrolimus and Mycophenolate Exposure and Subclinical Tubulo-Interstitial Inflammation in Low Immunological Risk Renal Transplants.

    I. Torres,1 A. Reisaeter,2 F. Moreso,1 A. Asberg,2 M. Perello,1 C. Dörje,2 J. Sellares,1 K. Midtved,2 H. Holdaas,2 D. Seron.1

    1Nephrology, Hospital Universitari Vall d'Hebron, Barcelona, Spain; 2Transplant Medicine, Rikshospitalet Oslo University Hospital, Oslo, Norway

    The aim is to evaluate the relationship between maintenance immunosuppression, subclinical inflammation (i-score plus t-score) and interstitial fibrosis/tubular atrophy (IF/TA) (ci-score plus ct-score) in paired…
  • 2017 American Transplant Congress

    Change in QTC Interval After Kidney Transplant.

    E. Lai, V. Acharya, D. Nguyen, E. Graviss, W. Suki.

    Houston Methodist Hospital, Houston, TX

    Cardiovascular (CV) disease is the leading cause of mortality in ESRD patients. A prolonged QTc interval on EKG is a predictor of adverse CV outcomes.…
  • 2017 American Transplant Congress

    Impact of Six-Month Surveillance Biopsies and Monitoring in Pediatric Renal Transplant Recipients.

    J. Lyons,1,2,3 D. Ranch,1,2 R. Hall,1,2,3 P. Maxwell,1,2,3 K. Hitchman,1,2 Y. Hirase,3 B. Crowther.1,2,3

    1University Health System, San Antonio, TX; 2University of Texas Health Science Center San Antonio, San Antonio, TX; 3University of Texas College of Pharmacy, Austin, TX

    Purpose: Evaluate the utility of surveillance biopsies and monitoring 6 months post-transplant.Methods: A retrospective single center chart review of pediatric renal transplant recipients from 01/2011–10/2015…
  • 2017 American Transplant Congress

    Importance of HLA-DR Expression in Pediatric Renal Transplant Biopsies.

    O. Moussa, S. Self, K. Twombley.

    Medical University of South Carolina, Charleston

    ObjectiveTo determine which types of injuries in pediatric kidney transplant patients were associated with HLA-DR expression.Design/MethodsA retrospective chart review was conducted of children receiving a…
  • 2017 American Transplant Congress

    A UNOS Database Analysis of Patient Outcomes from Kidney Alone versus Simultaneous Kidney Liver Transplants Utilizing Matched Donor Pairs.

    T. Zens, J. Danobeitia, P. Stahler, G. Leverson, R. Redfield III, A. D'Alessandro, L. Fernandez.

    Surgery - Division of Transplantation, University of Wisconsin - Madison, Madison, WI

    Introduction: Renal grafts used in simultaneous kidney liver (SLK) transplants are allocated by arbitrary clinical criteria without entering the kidney allocation algorithm. The goal of…
  • 2017 American Transplant Congress

    Subclinical Histologic Findings Are Observed in 25% of Stable Adult Liver Transplant Recipients (ALTRs) Screened for Immunosuppression Withdrawal (ISW): OPTIMAL (NCT02533180).

    S. Chandran,1 M. Abecassis,2 J. Levitsky,2 S. Feng,3 A. Humar,4 J. Emond,5 G. Klintmalm,6 A. Demetris,4 K. Much,7 L. Sun,1 A. Priore,8 D. Ikle,7 N. Bridges,8 M. DesMarais,1 B. Burrell,9 J. Markmann.10

    1ITN, San Francisco; 2Northwestern, Chicago; 3UCSF, San Francisco; 4UPMC, Pittsburgh; 5Columbia, New York; 6Baylor, Dallas; 7Rho, Chapel Hill; 8NIAID/NIH, Bethesda; 9ITN, Bethesda; 10MGH, Boston

    OPTIMAL is a 6-center ISW study in non-autoimmune, non-HCV ALTRs ≥3 yrs post-transplant (tx). Studies have shown a correlation between portal inflammation associated with tissue…
  • 2017 American Transplant Congress

    Plasma Cell Hepatitis in Primary Sclerosing Cholangitis Patients: 15-Year Experience at a Transplant Center.

    J. Putra,1 T. Schiano,2 M. Fiel.3

    1Pathology, Icahn School of Medicine at Mount Sinai, New York, NY; 2Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY

    Background: Plasma cell hepatitis (PCH) is an uncommon liver graft dysfunction which occurs in liver transplant (LT) recipients of different etiologies other than autoimmune hepatitis.…
  • 2017 American Transplant Congress

    Semi-Automated Pre-Donation Computed Topography (CT) Cortical Renal Volume to Predict Kidney Function in Live Kidney Donors 2 Years Following Donation.

    L.-X. Chen,1 G. Fananapazir,2 R. Benzl,2 M. Corwin,2 S. Stewart,3 C. Troppmann.4

    1Transplant Nephrology, UC Davis Medical Center, Sacramento, CA; 2Radiology, UC Davis Medical Center, Sacramento, CA; 3Biostatistics, UC Davis School of Medicine, Davis, CA; 4Transplant Surgery, UC Davis Medical Center, Sacramento, CA

    Objective: To evaluate whether volume of the remnant kidney based on pre-donation CT and donor age correlates with post-donation 2-year renal function in live kidney…
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