2017 American Transplant Congress
Digital Image Analysis of Pediatric Liver Allograft Biopsies Correlates with METAVIR Fibrosis Score.
1Children's Mercy Hospital, Kansas City, MO; 2University of Kansas Medical Center, Kansas City, KS
Background: Serial surveillance biopsies demonstrate post-transplant inflammation and fibrosis in long-surviving pediatric liver allografts. These changes can ultimately lead to cirrhosis and graft failure. However,…2017 American Transplant Congress
Systemic Immunosuppression in the Setting of Ocular Surface Stem Cell Transplantation.
1University of Cincinnati, Cincinnati, OH; 2Cincinnati Eye Institute, Cincinnati, OH
Purpose: To evaluate the success, tolerability, and side effects of systemic immunosuppression (SI) in patients undergoing ocular surface stem cell transplantation (OSST) under the SI…2017 American Transplant Congress
Prevention of Donor Specific Antibody Production After Skin Allografting by Mobilization of Endogenous Stem Cells Using a Combination of AMD3100 and Low-Dose FK506 in Rats.
Background: We have developed a stem cell mobilizing strategy that enables long-term liver and kidney allograft survival without sustained immunosuppression in small and large animals…2017 American Transplant Congress
Prediction of Positive Cytotoxic and Flow Crossmatches for Sensitized Wait List Candidates: Comparison of Luminex MFI, C1q and FcR Binding Assays.
Surgery, University of Cincinnati, Cincinnati
Clinical relevance of HLA antibodies identified in solid phase assays includes their ability to generate a positive crossmatch (XM) test, which often precludes transplantation. The…2017 American Transplant Congress
Awareness of Change in the Kidney Allocation System Among Dialysis Providers from Facilities with Low Waitlisting.
Background: In December 2014, the new kidney allocation system (KAS) was implemented and is expected to particularly benefit patients who have spent an extended time…2017 American Transplant Congress
Neighborhood Poverty and Racial/Ethnic Disparities in Access to Live Donor Kidney Transplantation in the US.
Johns Hopkins University, Baltimore
Black transplant candidates have substantially lower rates of live donor kidney transplantation (LDKT) than their White counterparts. We hypothesized that neighborhood poverty might play a…2017 American Transplant Congress
Reduced Racial Disparity in Outcomes of Kidney Transplant Recipients.
Alpert Medical School of Brown University, Providence, RI
OBJECTIVE: Earlier studies reported inferior outcomes among African-American (AA) compared with white kidney transplant (KT) recipients.DESIGN: Prospective database.SETTING: Single center.PATIENTS: During 1997-2015, 1102 patients underwent…2017 American Transplant Congress
Using Buccal Swabs for Deceased Organ Donor HLA Typing.
Aim: In some cases, getting enough cells from a deceased donor to perform crossmatches and DNA extraction for HLA typing is challenging. Specifically this is…2017 American Transplant Congress
Immunosuppressive Therapy and Acute Rejection in Combined Heart and Kidney Transplantation.
University of Louisville, Louisville
Background. This study evaluated the management of immunosuppressive therapy and the incidence of acute heart rejection within 1 year from concomitant heart-kidney transplantation (cHTKx) compared…2017 American Transplant Congress
DC-SIGN Functionalized Porous Silicon Nanoparticles Targeting to Human and Non-Human Primate Dendritic Cells.
Porous silicon (pSi) nanoparticles, modified to specifically target DC, provide a novel platform to carry and deliver immunosuppressive drugs. The aim was to conjugate DC-SIGN…
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