2017 American Transplant Congress
Ornithine Transcarbamylase Deficiency (OTC) in the Donor Liver, the Importance of Ascertaining the Cause of Death in the Brain Dead Donor.
The importance of ascertaining the cause of brain death in the donor is vital . We present a case of cadaveric liver donation (seg 2…2017 American Transplant Congress
Ex vivo Expanded Regulatory T cells Combined with Short-Term Costimulation Blockade Prevent Rejection of Vascularized Composite Allografts.
Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD
[Background] Reconstructive transplantation represents a valid therapeutic option after devastating tissue loss. Routine clinical application, however, is hampered by the toxicity of long-term maintenance immunosuppression.…2017 American Transplant Congress
Effects of Tofacitinib (JAK-3 Inhibitor) on De Novo HLA-A2 Antibody Production in a Mouse Model of Allo-Sensitization.
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
Purpose: Tofacitinib is a Janus Kinase Inhibitor currently approved by FDA for treatment of rheumatoid arthritis. In considering its effect in reducing B cell proliferation…2017 American Transplant Congress
Brain-Dead Donors Terminal Inflammation Is Associated to Delayed Graft Function in Kidney Transplant Recipients.
BACKGROUND: in kidney transplantation recipients, increased biomarkers of systemic inflammation before and after the transplant are associated to worse short- and long-term renal outcomes. However,…2017 American Transplant Congress
Three Induction Therapies on Patients with Delayed Graft Function After Kidney Transplantation, a Three-Year Outcome Analysis.
Departments of Medicine and Surgery, Tulane University School of Medicine, New Orleans, LA
We compare the 3-year outcomes of induction therapies with either methylprednisolone (group 1, n=58), basiliximab (group 2, n=56) or alemtuzumab (group 3, n=98) in primary…2017 American Transplant Congress
Access to Living Donor Kidney Transplantation in Nepal.
1JHU, Baltimore; 2Grinnell College, Grinnell; 3Human Organ Transplant Center, Bhaktapur, Nepal
Kidney transplantation is a relatively new and rapidly growing treatment modality in Nepal. Disparities in access to care are greatly amplified in a developing country…2017 American Transplant Congress
Concurrent Psychosocial Variables Confound Perioperative and Postoperative Care in Liver Transplant Recipients with Alcoholic Liver Disease.
Purpose: Liver transplant centers tend to focus primarily on duration of sobriety prior to consideration for transplantation in patients with alcoholic liver disease, with limited…2017 American Transplant Congress
A Novel Technique to Increase Donor Utilization: Our Experience Using High-Dose Tissue Plasminogen Activator Flush in Donation-After-Cardiac-Death Donors for Liver Transplantation.
Surgery, Montefiore Medical Center, Bronx, NY
The utilization of donation-after-cardiac-death (DCD) livers remains generally low. Strategies to address the perceived liabilities associated with DCD organs could influence their utilization in a…2017 American Transplant Congress
A Pilot Trial of Genotype-Guided Dosing versus Standard Clinical Dosing in Pediatric Solid Organ Transplants.
The Hospital for Sick Children, Toronto, ON, Canada
Purpose: Tacrolimus pharmacokinetics are influenced by age and variation in the CYP3A5 gene with CYP3A5 expressors (AA/AG) being fast metabolizers. The purpose of this trial…2017 American Transplant Congress
CD40/CD40 Ligand Signal Controls Cytotoxic Ability of Natural Killer Cells After Invariant Natural Killer T Cell Stimulation.
Because iNKT cells have powerful immune-regulatory function, an administration of iNKT cell ligand; α-galactosylceramide (aGC) is one of the potent strategies for induction of transplant…
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