2017 American Transplant Congress
Development and Validation of an FLF-Transplant Score to Predict Mortality of Patients with Fulminant Liver Failure.
The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
BACKGROUND & AIMS: We aimed to develop a simple prognostic model in predicting fulminant liver failure (FLF) patient mortality within 14 days after being listed…2017 American Transplant Congress
Exception Scores for Patients on the Liver Waiting List.
Liver waitlist candidates are prioritized for allocation using model for end-stage liver disease (MELD) scores, and some patients receive higher MELD scores through exception. The…2017 American Transplant Congress
Impact of Intensive Dosing of Mycophenolate on Pancreas Allograft Survival.
1Pharmacy, UW Health, Madison, WI; 2Transplant Surgery, UW Health, Madison, WI
Purpose: The primary objective was to evaluate the effect of mycophenolate (MPA) dicharge (DC) dose on pancreas allograft (PTX) survival. Secondary endpoints included patient survival…2017 American Transplant Congress
HLA Mismatching Does Not Have an Impact on Graft or Patient Survival in Simultaneous Kidney-Pancreas Transplantation. A Single Institution Experience.
Indiana University Health, Indianapolis
Purpose: There is conflicting data on whether the level and type of HLA mismatching (MM) has an impact on pancreas, kidney, or patient survival in…2017 American Transplant Congress
Safety and Decreased Inflammation of Early Double Cytokine Blockade (IL-1β and TNF-α) Facilitates Engraftment in Islet Allotransplantation.
Enhanced early islet engraftment offers the potential for improved graft function after islet allotransplantation (IT). Nine patients underwent IT under a fully completed prospective research…2017 American Transplant Congress
Long-Term Malignancy Risk in Kidney Transplant Recipients Treated with Cyclophosphamide Pre-Transplant for Native Glomerular Disease.
1Pharmacy, UW Health, Madison, WI; 2Nephrology, UW Health, Madison, WI
Purpose: To evaluate the incidence of malignancy in kidney transplant recipients who previously received cyclophosphamide for treatment of native glomerular disease.Methods: Single center study of…2017 American Transplant Congress
Induction of Durable Mixed Hematopoietic Chimerism and Immune Tolerance in Non-Human Primates.
Mixed hematopoietic chimerism is a promising approach to achieving transplantation tolerance. Transient mixed chimerism leads to renal allograft tolerance in about 70% of cynomolgus macaques…2017 American Transplant Congress
Liver Transplantation Tolerance Using Outbred Mice.
Success of organ transplantation currently depends on life-time immunosuppression, resulting in severe side effects. Induction of donor specific tolerance is ideal, which actually spontaneously occurs…2017 American Transplant Congress
Generation of Potent Monocytic Myeloid-Derived Suppressor Cells from Rhesus Macaque Bone Marrow.
Surgery (Transplant), University of Pittsburgh, Pittsburgh, PA
Background: Myeloid-derived suppressor cells (MDSC) have shown promise in inhibiting allograft rejection and in promoting transplant tolerance in rodent models. We recently reported that monocytic…2017 American Transplant Congress
High Eomesodermin Expression Correlates with Potent Human Allo-Reactive CD8+ Effector T Cells.
Surgery, University of Pittsburgh, Pittsburgh, PA
BackgroundThe transcription factors Eomesodermin (Eomes) and T-bet are thought to play critical roles in CD8+ effector memory T cell development. However, the role of Eomes…
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