2017 American Transplant Congress
Lymphoid Isolation as an Adjuvant Maneuver for Belatacept-Based Immunotherapy.
Purpose: Belatacept targets de novo alloimmune responses with minimal off target effects in renal transplantation, though adjuvant therapy is required for control of costimulation-blockade resistant…2017 American Transplant Congress
Generation of Autologous CMV and EBV-Specific T-Cell Lines from Seronegative Patients for Cell Therapy of Opportunistic Infections Following Kidney Transplantation.
Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) reactivations after kidney transplant are associated with substantial morbidity, especially in seronegative patients. Adoptive immunotherapy using virus-specific T cells…2017 American Transplant Congress
Non-Human Primate Auto-Immune Responses to Col V, Kα-1Tubulin and Vimentin Are P2X7R Dependent.
1Surgery, University of Wisconsin, Madison, WI; 2Medicine, University of Wisconsin, Madison, WI
Background: Auto-immune responses to Collagen type V (ColV) have been associated with coronary artery disease and lung or heart transplant rejection in humans and murine…2017 American Transplant Congress
Increased T Cell Exhaustion in Dialysis Patients.
Transplantation Research Center, Brigham and Women's Hospital, Boston, MA
Infection is a major complication post-transplantation. Evaluating the immune system prior to transplant may allow better optimization of immunosuppression dose. T cell exhaustion has been…2017 American Transplant Congress
C1q+ and IgG3+ De Novo Donor Specific Antibody Are Associated with Allograft Failure in a Multicenter Cohort.
Introduction: De novo donor specific antibody (dnDSA) is a risk factor for antibody mediated rejection and allograft loss, but dnDSA does not always lead to…2017 American Transplant Congress
Transcript Changes Associated with Graft Rejection Are Not Specific for Rejection Because They Are Shared with Tissue Responses to Wounding.
University of Alberta, Edmonton, Canada
The diagnosis of rejection by histology is based on the presence of relatively non-specific lesions. This is because the histology lesions are actually non-specific, but…2017 American Transplant Congress
Antibiotic Conservatorship in Orthotopic Liver Transplantation.
Post-orthotopic liver transplantation (OLT) infections, especially multidrug resistant organisms (MDRO), are implicated in poorer outcomes, fueling efforts to elucidate risk factors for hospital acquired infections.…2017 American Transplant Congress
Impact of STEEN vs Gelofusine as Perfusate During Normothermic Ex Vivo liver Perfusion on Outcome of Pig Liver Transplantation.
Multiorgan Transplant Program, Toronto General Hospital, Toronto, ON, Canada
European and North American clinical trials have used two different perfusate solutions for normothermic ex vivo liver perfusion (NEVLP): Gelofusine (bovine derived gelatin-based solution) and…2017 American Transplant Congress
EPOR2/ßcR2-Independendent Effects of Low-Dose Epoetin-a in Porcine Liver Transplantation.
Introduction: Ischemia-reperfusion injury (IRI) remains the key component of graft damage during transplantation. Mechanistically, cold-induced apoptosis, microcirculatory disturbances and radical oxygen species formation contribute to…2017 American Transplant Congress
Healthcare Resource Utilization for Patients with Donor-Specific Antibodies Post-Kidney Transplantation.
Formation of de novo donor-specific antibodies (dnDSA) against human leukocyte antigens (HLA) contributes to inferior kidney transplant (KT) outcomes. No data exist on healthcare resource…
- « Previous Page
- 1
- …
- 61
- 62
- 63
- 64
- 65
- …
- 181
- Next Page »