ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Donor SIRPa Polymorphism Modulates the Innate Immune Response to Allogeneic Grafts.

    H. Dai,1 A. Friday,1 K. Abou-Daya,1 A. Williams,1 M. Oberbarnscheidt,1 J. Danska,2 F. Lakkis.1

    1Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA; 2Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

    Mice devoid of T, B, NK, and innate lymphoid cells distinguish between self and allogeneic non-self despite the absence of an adaptive immune system. When…
  • 2017 American Transplant Congress

    Urinary Proteomic Biomarkers Discovery for Prediction of Acute Rejection in Kidney Transplant Recipients.

    H.-Y. Jung, R. Kim, S. Park, J. Park, K. Lee, E. Lee, J.-H. Lim, K. Kim, J.-Y. Choi, J.-H. Cho, S.-H. Park, Y.-L. Kim, C.-D. Kim.

    Internal Medicine, Kyungpook National University Hospital, Daegu, Republic of Korea

    Background: Early prediction and treatment of acute rejection are crucial in kidney transplant recipients (KTRs) to prevent allograft loss. Changes in the serum and urinary…
  • 2017 American Transplant Congress

    A Novel Computational HLA Matching Algorithm for Improving Donor-Recipient Histocompatibility and Graft Outcomes After Kidney Transplantation.

    V. Kosmoliaptsis,1 D. Mallon,1 S. Fuggle,2 R. Johnson,2 C. Watson,1 J. Bradley,1 C. Taylor.1

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom; 2NHS Blood and Transplant, Bristol, United Kingdom

    Introduction: Human Leukocyte Antigen (HLA) matching is a central objective of kidney allocation policies, but current assessment of histocompatibility is inadequate. Building on our previous…
  • 2017 American Transplant Congress

    Suppression of Inflammation by Withaferin A in Cerulein-Induced Pancreatitis Model Results in Improved Syngeneic Islet Engraftment.

    G. Yoshimatsu,1 M. Kanak,2 C. Chang,1 C. Darden,1 M. Lawrence,1 B. Naziruddin.3

    1Baylor Scott and White Research Institute, Dallas, TX; 2Virginia Commonwellth University, Richmond, VA; 3Baylor Simmons Transplant Institute, Dallas, TX

    Introduction: Chronic pancreatitis (CP) is characterized by inflammatory damage to acinar cells followed by islets. In clinical islet autotransplantation, patients with advanced stages of CP…
  • 2017 American Transplant Congress

    Comparing Outcomes of ABO Incompatible to DSA Positive/CDC-AHG Negative Kidney Transplantation.

    T. Kitrungphaiboon,1 N. Townamchai,1 D. Saengpanit,1 K. Iampenkhae,2 K. Jutivorakool,1 Y. Avihingsanon,1 K. Praditpornsilpa.1

    1Department of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand; 2Department of Pathology, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Bangkok, Thailand

    Back ground: Desensitization provides benefit in high risk kidney transplant recipients. We evaluated one year outcomes, including substances removal by apheresis techniques of ABO incompatible…
  • 2017 American Transplant Congress

    Comparison of Locoregional Therapies for Hepatocellular Carcinoma in Liver Transplant Recipients.

    M. Chen, B. Philosophe.

    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD

    Background: Locoregional therapies (LRT) have been employed in patients with hepatocellular carcinoma (HCC) to halt tumor progression and prevent waitlist drop out, as well as…
  • 2017 American Transplant Congress

    OPO Performance Metrics: Relationship with Kidney Transplant Program Performance Metrics and Kidney Utilization.

    A. Wey, N. Salkowski, B. Kasiske, A. Israni, J. Snyder.

    Scientific Registry of Transplant Recipients, Minneapolis, MN

    Organ procurement organization (OPO) performance metrics have been scrutinized due to the perceived disincentives of the regulatory system. In kidney transplantation, OPOs are evaluated on…
  • 2017 American Transplant Congress

    Impact of a Novel Prehabilitation Program in Kidney Transplant Candidates.

    M. McAdams DeMarco, H. Ying, A. Nastasi, D. Segev.

    Johns Hopkins, Baltimore, MD

    Background: Prehabilitation is the process of enhancing surgical patient functional capacity prior to surgery to improve tolerance for the upcoming physiologic stress. While prehabilitation has…
  • 2017 American Transplant Congress

    Genome-Wide Genotyping in > 1500 Liver Allograft Recipient and Donor Pairs Reveals Several Associations with Acute Cellular Rejection.

    B. Keating,1 B.-L. Chang,1 J. van Setten,2 B. Cole,1 L. Jennings,1 G. Klintmalm,3 A. Shaked.1

    1University of Pennsylvania, Philadelphia, PA; 2University Medical Center of Utrecht, UtrechT, Netherlands; 3Baylor Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX

    Introduction:Despite higher survival rates of liver allograft recipients through improvements in post-transplant surgery treatments, acute cellular rejection (ACR) remains a frequent & significant complication impacting…
  • 2017 American Transplant Congress

    Novel Therapies for Diabetic Kidney Disease.

    M. Nguyen, K. Kodama, M. Sarwal.

    University of California, San Francisco, San Francisco, CA

    Introduction: The development and progression of diabetic kidney disease (DKD) is thought to involve a combination of hemodynamic, metabolic, ischemic, and inflammatory factors; however, the…
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