ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    KDPI Obscures Trends in Absolute Donor Risk.

    N. Salkowski, S. Gustafson, A. Wey, J. Snyder.

    Scientific Registry of Transplant Recipients, Minneapolis, MN

    The kidney donor profile index (KDPI) is commonly used to measure deceased donor kidney quality based on the kidney donor risk index (KDRI) (Rao, et…
  • 2017 American Transplant Congress

    Correlation of Donor Clinical and Histopathological Characteristics with Graft Function in Kidney Transplant Recipients.

    M. Zachariah,1 C. Yip,1 M. Zachariah, I. Mallawaarachchi,2 A. Dweivedi,2 S. Patel,4 A. Gundroo,1 J. Tomaszewski,1 L. Lin,1 C. Shirley.1

    1Medicine, SUNY at Buffalo, Buffalo, NY; 2Biostatistics and Epidemiology, Texas Tech University, El Paso, TX; 3Pathology, SUNY at Buffalo, Buffalo, NY; 4Surgery, SUNY at Buffalo, Buffalo, NY

    Background: There is lack of consensus in the perceived accuracy of frozen biopsy interpretation. Interobserver variability in assessment of pre-implantation biopsies limits its value to…
  • 2017 American Transplant Congress

    Validation of a Novel Computational Approach for Predicting HLA Immunogenicity Based on Quantification of Structural and Surface Electrostatic Potential Differences Between Donor and Recipient HLA.

    V. Kosmoliaptsis,1 C. Kling,2 M. Robb,3 D. Collett,3 J. Bradley,1 C. Taylor,1 D. Kabelitz,2 D. Mallon.1

    1Department of Surgery, University of Cambridge, Cambridge, United Kingdom; 2University of Kiel, Kiel, Germany; 3NHS Blood and Transplant, Bristol, United Kingdom

    Background: Our preliminary work indicates that donor HLA immunogenicity in kidney and haematopoietic stem cell transplantation can be predicted by comparative assessment of donor and…
  • 2017 American Transplant Congress

    Mycophenolic Acid Needs Ca2+ to Exert Its Anti-inflammatory Action via Shedding of Toll-Like Receptor4 and Tumor Necrosis Factor Receptor 1.

    J. Kim,1 W. Yang,1 C. Baek,1 N. Han,2 S.-K. Park.1

    1Division of Nephrology, Department of Internal Medicine, Asan Medical Center, Seoul, Republic of Korea; 2Asan Institute for Life Science, Seoul, Republic of Korea

    Background Mycophenolic acid (MPA) has been used for many years to prevent transplantation rejection. Recently, it has been investigated for its anti-inflammatory effects. MPA can…
  • 2017 American Transplant Congress

    Nox4 and Oxidative Stress Mediate TGF-β1 Induced Human Kidney Proximal Cell Apoptosis in Ischemic Reperfusion Injury.

    S.-H. Yoon,1 S. Cho,1 D.-I. Kim,1 S.-R. Yoon,1 W.-M. Hwang,1 S.-L. Yu,2 J. Kang.2

    1Internal Medicine, Konyang University, Deajeon, Republic of Korea; 2Pharmacology, Konyang University, Daejeon, Republic of Korea

    AimsIschemia/reperfusion injury, resulting from hypoxic damage within a graft, is the leading cause of cell death and graft rejection. In this study, we investigated whether…
  • 2017 American Transplant Congress

    The Feared Five Fungal Infections in Kidney Transplant Recipients: 20-Year Experience at a Midwestern Center.

    S. Parajuli, A. Wick, S. Pandeya, B. Astor, J. Smith, A. Djamali, D. Mandelbrot.

    University of Wisconsin, Madison, WI

    Invasive fungal infections (IFI) are increasing in kidney transplant recipients (KTR). Here we present our experience with five feared IFIs in KTR transplanted between 01/01/1994…
  • 2017 American Transplant Congress

    Occult Hepatitis C Virus in Recipients of Kidney Transplantation: Prevalence and Clinical Implications.

    C. Jimenez,1 T. Olea,1 M. Lopez,1 I. Castillo,2 J. Bartolomé,2 J. Quiroga,2 E. Gonzalez,1 V. Carreño,2 R. Selgas.1

    1Nephrology, Hospital Universitario La Paz/IdiPaz, Madrid, Spain; 2Instituto de Estudios Virales, Madrid, Spain

    Occult HCV infection (OCI) is characterized by the presence of HCV- RNA in liver or in peripheral blood mononuclear cells in the absence of serological…
  • 2017 American Transplant Congress

    The Incidence, Mortality and Prediction Model for Fractures After Kidney Transplantation in the United States.

    X. Liu, S. Bae, M. McAdams DeMarco, D. Segev.

    JHU, Baltimore, MD

    Kidney transplant (KT) recipients are more likely than general population to have fractures. In the general population, fractures are associated with morbidity, mortality, and high…
  • 2017 American Transplant Congress

    Improvement in Inflammatory Response Follows Clearance of BKVN.

    E. Abuhelaiqa,1 S. Salvatore,2 J. Lee,1 J. Lee,1 T. Muthukumar,1 S. Seshan,2 D. Dadhania.1

    1Transplant Medicine, Weill Cornell Medicine, NY, NY; 2Dept. of Pathology, Weill Cornell Medicine, NY, NY

    Intro: Development of BKV nephropathy (BKVN) is a significant risk factor for graft loss. Proximate cause of graft loss is commonly attributed to acute/chronic rejection…
  • 2017 American Transplant Congress

    Donor and Recipient Outcomes with Trans-Umbilical Laparoendoscopic Single-Site Donor Nephrectomy.

    H. El Hennawy, A. Fahmy.

    Surgery Department, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia

    Introduction: Laparoendoscopic single-site donor nephrectomy (LESS-DN) emerged as an advancement to standard laparoscopic surgery with its advantage of using a single small incision concealed in…
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