2017 American Transplant Congress
Survival Benefit of Liver Transplantation for Patients with MELD Spike.
We recently showed that patients with a recent sudden MELD increase of >30% over 7 days (MELD spike) have higher waitlist mortality than patients with…2017 American Transplant Congress
Geographic Differences in Secular Trends of Liver Supply and Demand.
1JHU, Baltimore; 2US Naval Academy, Annapolis
Geographic disparities in access to deceased donor liver transplant reflect geographically disparate levels of supply of and demand for organs. Proposed policy changes like redistricting…2017 American Transplant Congress
Simultaneous Pancreas and Kidney Transplant (SPK) – The New Standard of Care for Uremic Patients with Type 2 Diabetes Mellitus (T2DM).
Surgery, SUNY Upstate Medical University, Syracuse, NY
Introduction: While a SPK is now considered standard of care for uremic T1 DM patients, it is not for T2DM (despite similar medical issues). The…2017 American Transplant Congress
Improved Method to Obtain High Islet Mass from Severely Fibrotic Pancreatitis Pancreases Intended for Clinical Islet Auto-Transplantation.
A total pancreatectomy and islet autotransplant (TPIAT) offers substantial pain relief and improved quality of life for pancreatitis patients. Isolating a large quantity of islet…2017 American Transplant Congress
Simultaneous Pancreas-Kidney Transplantation Can Be Safely Done on Dabigatran Therapy.
Due to convenient application, novel oral anticoagulants (NOAC), although not registered for renal failure, are an attractive therapeutic option. They are even more tempting in…2017 American Transplant Congress
Medication Adherence and Medicare B Coverage Among Transplant Recipients.
Purpose: Impact of nonadherence among transplant recipients has been well documented as a significant contributor of allograft failure. Medicare covers immunosuppressive medications for eligible patients…2017 American Transplant Congress
Increased Expression of Fibrillin-1 and Presence of Fibroblastic Reticular Cells in Treg-Rich Organized Lymphoid Structures (TOLS) of Accepted Kidney Allografts.
Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA
Background: Fibrillin-1, found in connective tissue, plays a role in the sequestration of TGF-b, and is produced by fibroblastic reticular cells (FRCs). It has been…2017 American Transplant Congress
Induction of Tolerance to Renal Allografts in Non Human Primates by Concomitant Donor-Matched Vascularized Osteomyocutaneous Allotransplantation.
Introduction: We hypothesized that hematopoietic stem cell (HSC) niches in bone marrow of vascularized osteomyocutaneous allografts (VOMA) will facilitate mixed chimerism (MC) and tolerance to…2017 American Transplant Congress
In Vitro Optimisation of the Immunotherapeutic Effects of Umbilical Cord Derived MSC.
Mesenchymal stromal cells (MSC) possess immunomodulatory properties and are low immunogenic, which are both important for their development into an effective cellular immunotherapy after organ…2017 American Transplant Congress
Senescence and Uremia Effects in Circulating T Cells Diverge in TREG Population and Cause T Cell Shift to a Memory Profile.
Elderly kidney transplant recipients(EKtx) have higher malignancies and infections rates, but lower acute rejection incidence. Senescence seems to result in shift to memory profile and…
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