ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Lung Preservation Solution Exposure at Cardiac Procurement Is Associated Increased Incidence of Coronary Arterial Vasculopathy.

    H. Copeland,1 V. Garcia,2 A. Sima,2 D. Baran,3 A. Mankind,4 G. Katlaps,1 N. Lewis,4 B. Dharmaj,1 J. Copeland.5

    1Cardiothoracic Surgery, McGuire VA Medical Center, Richmond, VA; 2Biostatistics, Virginia Commonwealth University, Richmond, VA; 3Cardiology, Beth Israel Medical Center Barnabas Health, Newark, NJ; 4Cardiology, McGuire VA Medical Center, Richmond, VA; 5Surgery, Division of Cardiothoracic Surgery, University of Arizona, Tucson, AZ

    Purpose: To evaluate cardiac recipient survival and incidence of coronary artery vasculopathy (CAV) in recipient hearts that have been exposed to lung preservation solution, Perfadex.Methods:…
  • 2017 American Transplant Congress

    Exploring Differential Antibody Response to Bortezomib in Heart Transplantation.

    K. Ghafourian, R. Hod-Dvorai, S. McCabe, N. Cool, M. Fine, M. Ackerman, J. Rich, J. Wilcox, E. Vorovich, A. Anderson, A. Tambur.

    Northwestern University, Chicago, IL

    Twelve heart transplant candidates (2013-2016) received Bortezomib (BTZ) for desensitization. Differential antibody (Ab) response was observed. BTZ cycles consisted of 4 injections of 1.3 mg/m2;…
  • 2017 American Transplant Congress

    CD16+ Monocytes and Skewed Macrophage Polarization Towards M2 Type Hallmark Heart Transplant Acute Cellular Rejection.

    T. van den Bosch,1 K. Caliskan,2 M. Kraaij,1 A. Constantinescu,2 O. Manintveld,2 P. Leenen,3 J. von der Thüsen,4 M. Clahsen-van Groningen,4 C. Baan,1 A. Rowshani.1

    1Internal Medicine and Transplantation, Erasmus University Medical Center, Rotterdam, Netherlands; 2Cardiology, Erasmus University Medical Center, Rotterdam, Netherlands; 3Immunology, Erasmus University Medical Center, Rotterdam, Netherlands; 4Pathology, Erasmus University Medical Center, Rotterdam, Netherlands

    Purpose: During acute heart transplant rejection, infiltration of lymphocytes and monocytes is followed by endothelial injury and eventually myocardial fibrosis. To date, no information is…
  • 2017 American Transplant Congress

    Renal Function, Albuminuria, and the Risk of Death and Graft Loss After Kidney Transplantation.

    N. Lam,1 M. Tonelli,2 K. Lentine,3 B. Hemmelgarn,2 F. Ye,1 K. Wen,1 S. Klarenbach.1

    1University of Alberta, Edmonton, Canada; 2University of Calgary, Calgary, Canada; 3Saint Louis University, St. Louis

    In 2012, the KDIGO guidelines updated the classification system for chronic kidney disease to include albuminuria. Whether this classification system prognosticates adverse clinical outcomes among…
  • 2017 American Transplant Congress

    Building a Conceptual Framework of Treatment Burden After Kidney Transplant: A Qualitative Study.

    E. Lorenz, J. Egginton, M. Stegall, A. Cheville, D. Eton.

    Mayo Clinic, Rochester

    Background: After kidney transplant, patients must negotiate complex medication regimens, lifestyle changes, laboratory monitoring and clinic appointments. The personal workload of healthcare and its impact…
  • 2017 American Transplant Congress

    Scoring of Distinct Tubular Injury Features and Assessment of Cellular Proliferation and of Non-Apoptotic Cell Death by the Novel Marker FACL4 Allow to Determine the Long-Term Prognosis of Renal Grafts.

    A. Bohlmann,1 J. Schmitz,1 A. Melk,1 R. Schmitt,1 I. Scheffner,1 V. Broeker,2 H. Haller,1 J. Metzger,3 J. Braesen,1 W. Gwinner.1

    1Hannover Medical School, Hannover, Germany; 2University of Gothenburg, Gothenburg, Sweden; 3Mosaiques Diagnostics, Hannover, Germany

    Acute tubular injury (ATI) is common in renal grafts and is related to an inferior long-term function. There is no consensus which of the tubular…
  • 2017 American Transplant Congress

    Regional Variation in Liver Donor Utilization Across the U.S.

    A. Friedman,1 P. Bagavan,2 S. Florman,3 H. Irving,1 B. Samstein,4 B. Schleich.1

    1LiveOnNY, New York, NY; 2Binghamton University, Binghamton, NY; 3Recanati/Miller Transplant Institute, New York, NY; 4Weill Cornell Medical College, New York, NY

    Unequal patient access to deceased donor liver transplantation across the U.S. has generated efforts to redesign the allocation system. Geographic disparities include the severity of…
  • 2017 American Transplant Congress

    Outcomes of Moderately to Severely Steatotic Grafts in Liver Transplantation: A Meta-Analysis.

    K. Bonner,1 C. Thongprayoon,2 W. Cheungpasitporn,1 M. Leise.1

    1Mayo Clinic, Rochester; 2Bassett Medical Center, Cooperstown

    Background/Objectives:There is a worldwide need to expand the pool of available liver grafts. Livers with >50% steatosis are discarded for orthotopic liver transplantation (OLT) by…
  • 2017 American Transplant Congress

    Impact of Early Pancreas Graft Failure on Patient and Kidney Graft Survival After Simultaneous Pancreas and Kidney Transplantation (SPK).

    A. Gruessner, M. Laftavi, V. Whittaker, Z. Acun, O. Pankowycz, R. Gruessner.

    SUNY Upstate Medical University, Syracuse, NY

    Introduction: In SPK transplants, the major risk factors for poor patient survival are early pancreas and/or kidney graft loss. In this study, we specifically examined…
  • 2017 American Transplant Congress

    Simultaneous Pancreas/Kidney Transplant Recipients Are Predisposed to Symptomatic CMV-Infection and Concomitant Infectious Complications.

    T. Schachtner,1,2,3 M. Zaks,1 A. Kahl,1 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany; 3Berlin Institute of Health BIH, Berlin, Germany

    Infections have increased in simultaneous pancreas/kidney transplant recipients (SPKTRs) with CMV-infection being the most important viral infection with adverse impact on patient and allograft outcomes.…
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