ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Bortezomib for Late Antibody-Mediated Rejection After Renal Transplantation: A Single Center Experience of 22 Cases.

    J. Choi, J. Jung, S. Chun, S. Shin, Y. Kim, D. Han.

    Department of General Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea

    Despite of tradifional treatments for AMR, such as plasapheresis, ingravenous immunoglobulin, and rituximab, current treatment for antibody-mediated rejection(AMR) after renal transplantation is insufficient. Recently, Bortezomib…
  • 2017 American Transplant Congress

    Outcomes of Active Screening for Carbapenem-Resistant Enterobacteriaceae among Liver Transplant Recipients.

    T. Bias,1 G. Malat,1 D. Lee,2 S. Talluri,2 K. Ranganna,2 S. Epstein,2 V. Patel,2 S. Guy.3

    1Department of Pharmacy, Drexel University College of Medicine, Philadelphia, PA; 2Department of Medicine, Drexel University College of Medicine, Philadelphia, PA; 3Department of Surgery, Drexel University College of Medicine, Philadelphia, PA

    Background: Preventive strategies to combat the transmission of Carbapenem-Resistant Enterobacteriaceae (CRE) include the use of active screening for CRE colonization; however, this approach is not…
  • 2017 American Transplant Congress

    Prevalence of Cutaneous Disease in Solid Organ Transplant Recipients: A 5-Year Study from a Medical -Surgical Transplant Dermatology Center.

    R. Allawh, A. Weiffenbach, K. Nadhan, M. Abdelmalek, C. Cusack, C. Chung.

    Dermatology, Drexel University College of Medicine, Philadelphia, PA

    Background: Solid organ transplant recipients (OTR) on chronic immunosuppression exhibit heightened risk of developing a myriad of cutaneous manifestations compared to non-transplant patients, including cutaneous…
  • 2017 American Transplant Congress

    Gene Editing of Keap1/Nrf2 in Human T Cells Using CRISPR-Cas9 to Improve Outcome from Ischemia Reperfusion Injury and Other T Cell Mediated Diseases.

    S. Noel,1 S. Lee,1 M. Sadasivam,2 A. Hamad,2 H. Rabb.1

    1Department of Medicine, Johns Hopkins University, Baltimore, MD; 2Department of Pathology, Johns Hopkins University, Baltimore, MD

    Background: T lymphocytes are important mediators of ischemia reperfusion injury (IRI) during organ transplantation. Using genetically engineered mice, we demonstrated that augmentation of Nrf2 dependent…
  • 2017 American Transplant Congress

    Alternations in Amplitude of Low Frequency Fluctuation in Renal Allograft Recipients That Received Tacrolimus or Sirolimus: An fMRI Study.

    J. Wen,1 X. Ni,1 L. Wu,2 G. Zheng,2 L. Zhang,2 J. Chen.1

    1National Clinical Research Center of Kidney Diseases, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; 2Department of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, Nanjing, China

    Objective The side-effects of resting tremor was common in renal transplant receipts receive tacrolimus. But the mechanism of this side-effect was unknown. This study want…
  • 2017 American Transplant Congress

    Immunosuppressant Costs for Medicare Part D and Kidney Transplant Recipients Since the Introduction of Generic Formulations in an Incident Kidney Transplant Population.

    M. Helmuth,1 M. Turenne,1 J. Park,2 Q. Liu,1 M. Oguntimein,3 S. Dutcher,3 R. Balkrishnan,4 J. Zee,1 A. Smith,1 A. Leichtman.1

    1Arbor Research Collaborative for Health, Ann Arbor, MI; 2U of Michigan, Ann Arbor, MI; 3Food and Drug Administration, Silver Spring, MD; 4U of Virginia, Charlottesville, VA

    Background: Substitution of generics (GEN) for brand name (BN) immunosuppressants (IS) has increased in kidney transplant recipients (KTR) since the introduction of GEN mycophenolate mofetil…
  • 2017 American Transplant Congress

    Understanding the Role of Induction Agents in Older versus Younger Kidney Transplant Recipients.

    Q. Huang, F. Ammary, M. McAdams-DeMarco, D. Segev.

    Johns Hopkins University, Baltimore, MD

    Background: There has been an increase in the number of older (over 65) KT recipients. Aging-related changes such as differences in immune senescence may influence…
  • 2017 American Transplant Congress

    Using Basiliximab Does Not Increase De Novo DSA Incidence but Reduces Cytomegalovirus Infections and Neoplastic Complications in Non-Sensitized Kidney Transplant Patients.

    M. Marron-Wojewodzki,1 I. Szwarc,1 C. Rene,2 J.-F. Eliaou,2 G. Mourad,1 M. Le Quintrec.1,3

    1Department of Nephrology, Dialysis and Transplantation, Hôpital Lapeyronie, Montpellier University Hospital, Montpellier, France; 2Departement of Immunology, Hôpital Saint Eloi, Montpellier University Hospital, Montpellier, France; 3Inserm U1183, IRMB, Hôpital Saint Eloi, Montpellier University Hospital, Montpellier, France

    Background. In kidney transplantation, de novo donor specific antibodies (dnDSA) are associated with antibody-mediated rejection (AMR) and graft failure. After dnDSA development, 24% of the…
  • 2017 American Transplant Congress

    Endoscopic Therapy of Bile Duct Strictures After Liver Transplant.

    H. Woller, P. Mantry, A. Mejia, S. Cheng, C. Fasola.

    Gastroenterolgy and Hepatology, Methodist Dallas Medical Center, Dallas, TX

    Background and Aims: Common Bile Duct Strictures (CBDS) are a significant source of morbidity after liver transplantation (LT) We report our outcomes of endoscopic treatment…
  • 2017 American Transplant Congress

    Extending the Limit for Living Donor Liver Transplantation: Similar Outcomes After Left vs. Right Lobe Graft, a Propensity Score Analysis.

    T. Wong, K. Ng, J. Fung, K. Chok, A. Chan, C. Lo.

    Surgery, The University of Hong Kong, Hong Kong, Hong Kong

    BackgroundThis study aimed to investigate the impact of graft selection (left vs. right lobe) in LDLT.MethodThis was a retrospective study that included all patients who…
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