Am J Transplant, Volume 17, Suppl 3 Archives - Page 49 of 181 - ATC Abstracts

2017 American Transplant Congress
Using Donors with False Positive HIV Tests – An Unexpected Benefit of the HOPE Act.
C. Durand,¹ S. Halpern,¹ G. Bismut,¹ B. Doby,¹ N. Desai,¹ A. Cameron,¹ S. Florman,² S. Lerner,² S. Huprikar,² J. Locke,³ S. Mehta,³ P. Stock,⁴ N. Neidlinger,⁵ D. Brown,¹ B. Haydel,² A. Redd,^1,6 A. Massie,¹ A. Tobian,¹ D. Segev.¹
¹JHU, Baltimore, MD; ²Mount Sinai, New York, NY; ³UAB, Birmingham, AL; ⁴UCSF, San Francisco, CA; ⁵Donor Network West, San Ramon, CA; ⁶NIH, Bethesda, MD
Deceased donors are screened for HIV infection using anti-HIV antibody (Ab) and nucleic acid testing (NAT). Historically, organs were discarded in cases of a suspected…
2017 American Transplant Congress
When Does the Learning Curve End? A High-Volume Single Center Experience with Laparoscopic Donor Nephrectomy Over 16 Years.
S. Yamanaga,^1,2,3 A. Posselt,¹ C. Freise,¹ C. Niemann,¹ A. Rosario,¹ D. Fernandez,¹ T. Kobayashi,³ A. Ahearn,⁴ M. Tavakol,¹ S.-M. Kang.¹
¹Division of Transplant Surgery, Department of Surgery, University of California San Francisco, San Francisco, CA; ²Department of General Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan; ³Department of Renal Transplant Surgery, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan; ⁴Department of Transplant Surgery, UMass Memorial Medical Center, Worcester, MA
Purpose: No studies for any type of surgery have examined learning curves beyond a decade or 100 cases because surgeon turnover and lack of complete…
2017 American Transplant Congress
Donation After Circulatory Death (DCD) Kidneys Are More Likely to Be Discarded than Kidneys from Neurologically Brain Dead Donors (NBD).
J. Gill,¹ C. Rose,¹ J. Lesage,¹ Y. Joffres,¹ J. Gill,¹ K. O'Connor.²
¹UBC, Vancouver, Canada; ²LifeCenter, Seattle
Strategies to decrease organ discard are needed. We determined the adj odds of discard of DCD vs NBD kidneys in kidney donor profile index (KDPI)…
2017 American Transplant Congress
Cultural Competency of a Mobile, Customized Patient Education Tool for Improving Potential Kidney Transplant Recipients' Knowledge and Decision-Making.
D. Axelrod,¹ C. Kynard-Amerson,² D. Wojciechowski,³ K. Lentine,⁴ M. Schnitzler,⁴ J. Peipert,² A. Waterman.²
¹Surgery, East Carolina University, Greenville, NC; ²Medicine, UCLA, Los Angeles, CA; ³Medicine, Massachusetts General Hospital, Boston, MA; ⁴Transplant, Saint Louis University, St. Louis, MO
Patients with ESRD face a complex array of treatment options as a result of the revised kidney allocation system. Decision aids improve patient care through…
2017 American Transplant Congress
Is There an Association Between Number of Outpatient Primary Care Visits (OPV) and Outcomes in Kidney Transplantation (KTP)?
A. O'Shea, R. Kalil.
Medicine, University of Iowa Carver College of Medicine, Iowa City, IA; Department of Veterans Affairs, Comprehensive Access and Delivery Research Evaluation (CADRE), Iowa City, IA
Background: Periodic outpatient primary care visits (PCV) after KTP is recommended to achieve optimal outcomes, but annual rates of PCV by KTP recipients is not…
2017 American Transplant Congress
Experience with Belatacept (CTLA4-Ig) Conversion in Highly HLA Sensitized (HS) and ABO-Incompatible (ABOi) Patients Who Received Incompatible Kidney Transplants Post Desensitization (DES).
J. Choi,¹ A. Peng,¹ A. Vo,¹ E. Huang,¹ R. Najjar,¹ S. Louie,¹ A. Kang,¹ S. Ge,¹ M. Toyoda,¹ X. Zhang,² S. Jordan.¹
¹Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA; ²HLA Laboratory, Cedars-Sinai Medical Center, Los Angeles, CA
Introduction: Recent experience with belatacept (bela) in nonsensitized kidney tx recipients suggest that costimulatory blockade in a CNI-free environment results in superior graft survival &…
2017 American Transplant Congress
The miRNome of EBV+ PTLD is Distinct from EBV+ Infectious Mononucleosis.
Y. Balachandran,¹ V. Kaul,¹ E. Maloney,¹ A. Harris-Arnold,¹ K. Weinberg,² S. Boyd,² D. Bernstein,² C. Esquivel,¹ O. Martinez,¹ S. Krams.¹
¹Transplant Immunology Lab/Division of Abdominal Transplant, Stanford University, Stanford; ²Stanford University, Stanford
Post-transplant lymphoproliferative disorder (PTLD) is a potentially fatal complication of organ transplantation commonly associated with Epstein Barr virus (EBV) infection. More than 90% of the…
2017 American Transplant Congress
Maribavir for Treatment of Cytomegalovirus Infections Resistant or Refractory to Ganciclovir or Foscarnet in Solid Organ Transplant Recipients: A Phase 2 Study.
M. Pereira,¹ F. Silveira,² G. Papanicolaou,³ A. Langston,⁴ R. Avery,⁵ A. Wijatyk,⁶ J. Wu,⁶ M. Boeckh,⁷ F. Marty,⁸ S. Villano.⁹
¹Columbia University Medical Center, New York, NY; ²University of Pittsburgh Medical Center, Pittsburgh, PA; ³Memorial Sloan Kettering Cancer Center, New York, NY; ⁴Winship Cancer Institute, Atlanta, GA; ⁵Johns Hopkins University, Baltimore, MD; ⁶Shire, Lexington, MA; ⁷Fred Hutchinson Cancer Research Center, Seattle, WA; ⁸Brigham and Women's Hospital, Boston, MA; ⁹Shire (At Time of Study), Wayne, PA
Study NCT01611974 assessed safety, tolerability, and antiviral activity of maribavir (MBV) for treatment of resistant or refractory (R/R) CMV infections among transplant recipients. Those aged…
2017 American Transplant Congress
Regulatory T Cells Inhibit Plasmablast Formation and IgG Production by Tempering T Follicular Helper Cell Function.
P. Fadakar, C. Macedo, M. Yamada, K. Hadi, D. Metes.
Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh, PA
Background: Donor-specific antibodies (DSA) are an important biomarker for acute rejection, transplant glomerulopathy and late allograft failure in kidney transplantation. Few studies have characterized the…
2017 American Transplant Congress
HLA Donor-Specific Antibody (DSA) Negative Antibody-Mediated Rejection (AMR): Incidence, Treatment and Outcomes.
R. Redfield, S. Parajuli, W. Zhong, B. Astor, A. Djamali, D. Mandelbrot.
UW, Madison
Background: Banff 2013 criteria for the diagnosis of antibody-meditated rejection (AMR) in kidney transplants require the presence of donor-specific antibody (DSA). Clinical significance of histological…