2017 American Transplant Congress
Experience with Obinutuzumab (Type II Anti-CD20) in Kidney Transplant Patients with Donor Specific Antibody (DSA+) Antibody Mediated Rejection.
Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA
Introduciton:Rituximab is a type I chimeric IgG1 anti-CD20 antibody that has revolutionized the management and treatment of B-cell malignancies, and numerous autoimmune diseases. In addition,…2017 American Transplant Congress
TIM-4 Identifies Pro-Inflammatory B Effector Cells That Are Potent Drivers of Alloimmunity and Allograft Rejection Through Expression of Both IFN-γ and IL-17.
Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pittsburgh
B cells can either augment or inhibit immune responses due to the presence both regulatory (Bregs) and effector (Beff) B cells expressing anti- or pro-…2017 American Transplant Congress
CD47 Blockade Reduces Ischemia/Reperfusion Injury in Donation After Cardiac Death Rat Kidney Transplantation.
Purpose: We evaluated the potential effects of antibody-mediated CD47 blockade to modulate vascular endothelial nitric oxide activity and reduce ischemia reperfusion injury in a rat…2017 American Transplant Congress
Importance of Acquisition of Carbapenemase (KPC)-Producing Enterobacteriaceae in Solid Organ Transplant Recipients: A Single-Center Experience.
Background: Among multi-drug resistant bacteria, carbapenem-resistant Enterobacteriaceae (CRE) is recently spreading in several countries. Carbapenemase-producing (CP) Enterobacteriaceae (CPE) has great clinical importance because it could…2017 American Transplant Congress
The Relationship Between Frailty and Decreased Physical Performance with Death on the Kidney Transplant Waiting List.
Background: Frailty and decreased physical performance are associated with poor outcomes after kidney transplant. Less is known about their relationship with pre-transplant outcomes. The aim…2017 American Transplant Congress
State Population Health and Center-Level Variation in Rate of Living Kidney Donation.
University of Alabama at Birmingham, Birmingham
Background: Comorbid conditions that exclude individuals from living kidney donation are highly prevalent in the United States, but the relationship between population characteristics and the…2017 American Transplant Congress
A Multidimensional Prognostic Score and Nomogram to Predict Kidney Transplant Survival: The Integrative Box (iBox) System.
The transplant field currently lacks of robust risk stratification models leading to major problems for clinical care, clinical trials, and medical progress. The goal of…2017 American Transplant Congress
Outcomes of Hand Assisted Laparoscopic Right Donor Nephrectomy, Single Center Experience.
Transplant Surgery, The Ohio State Wexner Medical Center, Columbus, OH
Right donor nephrectomy,especially when conducted laparoscopically,has not been accepted by most transplant surgeons because of the consequent short right renal vein and the possible increased…2017 American Transplant Congress
Induction Therapy in Low Risk Elderly Kidney Transplant Recipients: Donor Factors.
Johns Hopkins, Baltimore; University of Colorado, Denver
It is not known whether depleting induction is needed in low-risk elderly kidney transplant (KT) recipients in whom concern for infectious and complications is higher…2017 American Transplant Congress
A Mutation of the Erythropoietin Receptor Correlates with Improved Function of Deceased-Donor Renal Transplants.
Erythropoietin (Epo) protects renal tubular cells from ischemia/reperfusion injury in experimental transplantation, suggesting a relevant effect of erythropoietin receptor (EPOR) mediated signalling. Previously 6 mutations…
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