2017 American Transplant Congress
Endocapillary NK Cells Are Increased in Indication Renal Transplant Biopsies with Antibody and T Cell Mediated Rejection.
Pathology, University of Michigan Medical School, Ann Arbor, MI
Detection of NK cell transcripts in renal transplant biopsies is associated with antibody mediated rejection (AMR). Similarly, quantification of endocapillary NK cells in paraffin tissue…2017 American Transplant Congress
One-Year Graft and Patient Survival of Deceased Donor Kidney Transplants Under KAS.
Background: The new kidney allocation system (KAS) was implemented on 12/4/14 and led to more transplants for highly sensitized and long-term dialysis patients. Clinical characteristics…2017 American Transplant Congress
Comparing the Role of Post-Transplant Readmissions and Bed Days on Total One Year Cost of Care.
This study examines the marginal impact of readmissions and total bed days during the 90-day period following transplant in order to better understand drivers of…2017 American Transplant Congress
VO2peak: A Significant Marker of All-Cause Mortality Among Patients with End-Stage Renal Disease Being Evaluated for Kidney Transplant.
1Mayo Clinic AZ, Phoenix; 2ASU, Tempe
Background: Peak oxygen uptake (VO2peak), obtained from cardiopulmonary exercise testing is a marker of functional capacity and a modifiable risk factor. VO2peak is a strong…2017 American Transplant Congress
Belatacept After Kidney Transplantation in Adolescents.
Pediatric Nephrology, Hannover Medical School, Hannover, Germany
Background: Regardless of recipient age at kidney transplantation (KTx), patients are at greatest risk for graft loss in adolescence. This is in part due to…2017 American Transplant Congress
A Regulatory T Cell (Treg)-Intrinsic Role for p27kip1 in Acquired Transplant Tolerance.
Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA
We previously found that the cyclin-dependent kinase CDK2 phosphorylates the Treg transcription factor Foxp3, targeting it for proteolytic degradation. Treg with defective CDK2 activity express…2017 American Transplant Congress
Donor-Derived Cell-Free DNA Correlates with Antibody-Mediated Rejection in Kidney Allografts.
Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a noninvasive test of allograft injury that may enable more frequent, quantitative, and safer assessment of allograft rejection and…2017 American Transplant Congress
Simplified Classification of Pancreas Transplant Insufficiency.
To date, the definition of pancreas transplant (PTX) failure is based on the need for antidiabetic therapy. However, as even a marginal PTX function can…2017 American Transplant Congress
Renal Function After Liver Transplantation Alone in Patients Meeting the Proposed UNOS Simultaneous Liver-Kidney (SLK) Criteria.
Background & Aim: The United Network for Organ Sharing (UNOS) has proposed criteria for simultaneous liver and kidney transplantation (SLK) incorporating strict definitions for eligibility…2017 American Transplant Congress
The Objective Liver Frailty Index Significantly Improves the Clinician “Eyeball Test” to Predict Mortality in Liver Transplant Candidates.
Background: Frailty is a critical determinant of waitlist outcomes. The most commonly-used test to assess frailty in liver transplant (LT) candidates is the “eyeball test”,…
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