ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    The Immunophenotype of Peritubular Capillaritis in Renal Transplant Biopsies.

    T. Chen,1 L. Rasch,1 T. Al Johani,2 H. McPhail,1 M. Willicombe,3 A. McLean,3 J. Galliford,3 T. Cook,1 C. Roufosse.1

    1Centre for Complement and Inflammation Research, Imperial College, London, United Kingdom; 2Cellular Pathology, King Saud University, Riyadh, Saudi Arabia; 3Dept Renal Medicine, Imperial College Healthcare NHS Trust, London, United Kingdom

    Background: Peritubular capillaritis (ptc) is a feature of acute antibody-mediated rejection (ABMR) in the renal allograft. However, it is not an specific feature for ABMR…
  • 2017 American Transplant Congress

    Proteins in Preservation Fluid Predict Delayed Graft Function of Kidneys from Donors After Circulatory Death.

    B. van Balkom,1 H. Gremmels,1 L. Ooms,4 R. Toorop,2 F. Dor,5 O. de Jong,1 L. Michielsen,1 G. de Borst,2 W. de Jager,3 A. van Zuilen,1 M. Verhaar.1

    1Nephrology and Hypertension, UMC Utrecht, Utrecht, Netherlands; 2Vascular Surgery, UMC Utrecht, Utrecht, Netherlands; 3Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands; 4Surgery, Erasmus MC, Rotterdam, Netherlands; 5Renal and Transplant Services, Imperial College Healthcare NHS Trust, London, United Kingdom

    Background and objectivesKidney transplantation is the preferred treatment for end-stage kidney disease, and donor kidney shortage urges proper donor-recipient matching. Zero-hour biopsies provide predictive value…
  • 2017 American Transplant Congress

    Early Steroid Withdrawal and Infection in Kidney Transplant Recipients.

    S. Bae, C. Durand, L. Kucirka, S. DiBrito, R. Avery, J. Garonzik Wang, D. Segev.

    Johns Hopkins School of Medicine, Baltimore, MD

    One third of kidney transplant (KT) recipients currently undergo early steroid withdrawal (ESW). Although ESW may slightly increase the risk of rejection in certain subgroups,…
  • 2017 American Transplant Congress

    An Analysis of Tacrolimus XL Dosing in Obese Kidney Transplant Recipients.

    N. Jasiak, J. Thielke, K. Progar, J. Chen, C. Adams, E. Benedetti, P. West-Thielke.

    Univ of Ill, Chicago

    Background:Tacrolimus extended-release (XL) is utilized in many immunosuppressive regimens post-kidney transplantation. Current dosing recommendation for the XL formulation in renal transplant (txp) is 0.15 mg/kg/day…
  • 2017 American Transplant Congress

    More Than Renal Function: Use of Belatacept to Improve Drug Toxicities.

    E. Cohen,1 B. Knight,3 W. Asch.2

    1Department of Pharmacy, Yale-New Haven Hospital, New Haven, CT; 2Department of Nephrology, Yale University, New Haven, CT; 3UCONN School of Pharmacy, Storrs, CT

    Background: Data with belatacept has demonstrated that patients on de novo belatacept have better renal function and improved patient and graft survival seven years post-transplant.…
  • 2017 American Transplant Congress

    Evolution of CCR4highCD4+ Subpopulations in Renal Graft Blood After Steroid Withdrawal: A Prospective, Randomized, Controlled Study in Parallel Groups. Preliminary Results.

    J. Alonso-Titos,1 P. Ruiz-Esteban,1 E. Palma,1 A. Caballero,2 E. Sola,1 M. Cabello,1 T. Vazquez,1 A. Duarte,1 C. Jironda,1 D. Hernandez.1

    1Nephrology, Regional University Hospital and Malaga University, IBIMA, RD16/0009/0006, Malaga, Spain; 2Immunology, Regional University Hospital of Malaga, Malaga, Spain

    Introduction:Steroids are a mainstay of immunosuppression after kidney transplant (KT). The infiltration into the graft of active T cells following KT depends on the expression…
  • 2017 American Transplant Congress

    Lipid Abnormalities and Cardiovascular Events After Early Conversion to Everolimus in Kidney Transplant Recipients with Pretransplant Diabetes: 24-Month Analysis from Elevate Study.

    M. van der Giet,1 J. de Fijter,1 F. Oppenheimer,1 G. Russ,1 P. Lopez,2 G. Bader,2 J. Cruzado,1 H. Holdaas.1

    1ELEVATE Study Group, Berlin, Germany; 2Novartis Pharma AG, Basel, Switzerland

    PURPOSE: Pretransplant (preTx) diabetes is an independent risk factor for cardiovascular (CV) events, and posttransplant (post-Tx) hyperlipidemia further increases CV risk. To analyze the influence…
  • 2017 American Transplant Congress

    Propensity-Matched Comparison of Diabetic Patients and Non-Diabetic Patients in Living Donor Kidney Transplantation.

    C. Baek,1 H. Kim,1 W. Yang,1 D. Han,2 S.-K. Park.1

    1Division of Nephrology, Department of Internal Medicine, Asan Medical Center, Seoul, Republic of Korea; 2Department of Surgery, Asan Medical Center, Seoul, Republic of Korea

    Background: Kidney transplantation (KT) reportedly provides a significant survival advantage over dialysis in diabetic patients. However, KT outcome in diabetic patients compared with that in…
  • 2017 American Transplant Congress

    Long Term Outcomes of Adult Kidney Transplants from Small Single Pediatric Donors Are Equivalent to Standard Criteria Donors.

    R. McMillan, K. Gray, T. Khader, A. Jabri, J. Kim, A. Watkins.

    Surgery, Weill Cornell Medicine, New York, NY

    PurposeWe analyzed long term outcomes of adult kidney transplant recipients from single pediatric donors at a large volume center.MethodsA retrospective review of 90 adult kidney…
  • 2017 American Transplant Congress

    Successful Implementation of a Pneumococcal Vaccination Program for Pediatric Kidney Transplant Recipients.

    K. Sprott, S. Nadig, K. Twombley.

    Medical University of South Carolina, Charleston

    Vaccine preventable diseases remain a serious problem among transplanted patients. Many children remain under vaccinated after a kidney transplant because of a lack of physician…
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