ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Rabbit Anti-Human Thymocyte Immunoglobulin (rATG) for Rescue Treatment of Chronic Antibody-Mediated Rejection (cAMR) After Pediatric Kidney Transplantation.

    L. Pape, T. Ahlenstiel-Grunow, J. Drube, M. Kreuzer, C. Lerch, N. Kanzelmeyer, S. Wente, I. Hennies, Y. Cihan.

    Pediatric Nephrology, Hannover Medical School, Hannover, Germany

    Background. Chronic antibody-mediated rejection (cAMR) is the leading cause of long-term graft loss after kidney transplantation. Treatment guidelines include rituximab, immunoadsorption, immunoglobulins and/or bortezomib, but…
  • 2017 American Transplant Congress

    Combined Dual-Kidney Liver Transplantation in the United States: A Review of UNOS/OPTN Data Between 2002 and 2012.

    G. Shekhtman, E. Huang, E. Lum, G. Danovitch, P.-T. Pham, B. Abdalla, S. Bunnapradist.

    Department of Medicine, UCLA, Los Angeles, CA

    BackgroundSimultaneous liver-kidney transplantation (SLKT) has increased demand for donor kidneys during a national organ shortage. In kidney-alone recipients, dual kidney transplantation (DKT) using “marginal” donor…
  • 2017 American Transplant Congress

    This is Why We Can't Have Nice Things- Real World Experience with Everolimus in Livers.

    C. Perez,1 J. Fleming,1 M. Sell,1 B. O'Brien,1 A. Rogers,1 I. Lee,1 C. Mardis,1 A. Mardis,1 N. Patel,1 H. Meadows,1 N. Pilch,2 K. Chavin,2 D. Dubay,2 D. Taber.2

    1Pharmacy, Medical University of South Carolina, Chareleston, SC; 2Surgery, Medical University of South Carolina, Charleston, SC

    Purpose: To determine if discontinuation rates of everolimus (RAD) in clinical practice is higher than the 30% demonstrated in trials.Methods: This was a retrospective cohort…
  • 2017 American Transplant Congress

    Liver Allograft Hepatitis and Graft Loss After Hepatitis C Clearance.

    D. Bruno, S. Brown, S. Hanish, J. LaMattina, W. Hutson, S. Kottilil, W. Twadell, R. Barth.

    Surgery, University of Maryland School of Medicine, Baltimore, MD

    Successful HCV therapies should improve inferior outcomes of liver transplantation (LT) for HCV cirrhosis. We hypothesize certain patients may be predisposed to heterologous immunity that…
  • 2017 American Transplant Congress

    Lower Rates of Living Donation Among Transplant Centers Located in the Stroke Belt.

    R. Reed, B. Shelton, P. MacLennan, M. Hanaway, V. Kumar, R. Gaston, J. Locke.

    University of Alabama at Birmingham, Birmingham

    Background: The prevalence of comorbid disease continues to increase in the United States, particularly in areas like the Stroke Belt, but it is unknown whether…
  • 2017 American Transplant Congress

    Renal Function Variability Is a Significant and Independent Risk Factor for Graft Loss and Death in Kidney Transplantation.

    D. Taber,1 Z. Su,1 A. Posadas,1 D. Dubay,1 C. Bratton,1 J. McGillicuddy,1 K. Chavin,1 T. Srinivas,2 S. Nadig,1 V. Rohan,1 P. Baliga.1

    1Transplant, MUSC, Charleston, SC; 2Transplant, Intermountain Healthcare, Salt Lake City, UT

    Previous studies have demonstrated that the magnitude of decline in renal function can predict graft loss after kidney transplant (KTX), but there is limited research…
  • 2017 American Transplant Congress

    25-Hydroxyvitamin D [25(OH)D], but Not 1,25-Dihydroxyvitamin D [1,25(OH)2D], Independently Predicts Kidney Graft Failure: The Wisconsin Allograft Recipient Database (WisARD).

    B. Astor,1 M. Melamed,2 D. Mandelbrot,1 A. Djamali.1

    1University of Wisconsin School of Medicine and Public Health, Madison, WI; 2Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY

    Vitamin D deficiency is common in chronic kidney disease and is associated with cardiovascular events and mortality. Kidney transplant recipients are at elevated risk of…
  • 2017 American Transplant Congress

    Transplantation of Hepatitis C Kidneys to Hepatitis C Recipients Confers Significantly Shorter Waiting Times in the Era of the New Kidney Allocation System.

    B. Concepcion, A. Langone, B. Edmundson, J. Johnson, A. Rajput, T. Johnson, D. Rybacki, D. Hale, R. Forbes.

    Nashville VA Medical Center, Nashville, TN

    Background: Prior to the new KAS, transplantation with HCV+ compared to HCV- kidneys provided shorter waiting times on the deceased donor list. In the current…
  • 2017 American Transplant Congress

    Cost-Effectiveness of Renal Machine Perfusion Use After Long Cold Ischemia Time.

    A. Matos,1 D. Malheiro,3 S. Morgado,1 L. Requi[acirc]o-Moura,1 M. Souza-Durão,1,2 E. Tonato,1 M. Nogueira,1 M. Borrelli,1 A. Pacheco-Silva.1,2

    1Renal Transplant, Hospital Israelita Albert Einstein, São Paulo, Brazil; 2Nephrology, Universidade Federal de São Paulo, São Paulo, Brazil; 3Health Economics Department, Hospital Israelita Albert Einstein, São Paulo, Brazil

    High cold ischemia time (CIT) and inadequate care of donors in Brazil lead to a high incidence of delayed graft function (DGF), 60%-70%, and as…
  • 2017 American Transplant Congress

    Long-Term Liver and Kidney Survival Following Combined Liver-Kidney Transplantation, with or without Preformed Donor-Specific Antibodies.

    A. Del Bello,1 O. Bestard,2 J. Visentin,3 N. Congy-Jolivet,1 L. Couzi,3 M. Neau-Cransac,3 F. Jambon,3 N. Kamar.1

    1Nephrology and Organ Transplant Department, CHU Toulouse, Toulouse, France; 2Nephrology and Kidney Transplant Department, Bellvitge University Hospital, Barcelona, Spain; 3Nephrology and Kidney Transplant Department, CHU Bordeaux, Bordeaux, France

    Introduction: Successful kidney transplantation despite a positive crossmatch is well known after combined liver-kidney transplantation (CLKT). However, recently, concerns regarding the impact of preformed anti-HLA…
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