ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Biodistribution of Adipose Derived Regenerative Cells Administered via the Renal Artery in Novel Rat Transplant Model.

    R. Ghita,1,2 R. Lathan,2 D. Hillyard,2 P. Mark,1,2 M. Clancy.1,2

    1Glasgow Renal and Transplant Unit, Queen Elizabeth University Hospital Glasgow, Glasgow, United Kingdom; 2Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom

    Introduction:A novel rodent model of ischaemia- reperfusion injury (IRI) has shown significant improvement in renal function and histology after administration of adipose derived regenerative cells…
  • 2017 American Transplant Congress

    Analysis of ApoL1 and MYH9 Genetic Polymorphisms Among the Hispanic Kidney Allograft Recipients.

    Y. Chang,1,2 T. Shah,1,3 D. Min.1

    1Western University of Health Sciences, Pomona, CA; 2Mendez National Institute of Transplantation Foundation, Los Angeles, CA; 3St. Vincent Medical Center, Los Angeles, CA

    Introduction: Genetic polymorphisms of Apolipoprotein 1 (ApoL1) and non-muscle heavy chain 9 (MYH9) genes are known to be strongly associated with focal segmental glomerulosclerosis, HIV-associated…
  • 2017 American Transplant Congress

    Mitochondrial Dysfunction Is a Common Feature of Injury in Donor Kidneys After Brain and Circulatory Death.

    M. Lo Faro,1 M. Akhtar,1 H. Huang,1 M. Kaisar,1 R. Rebolledo,2 K. Morten,1 L. Heather,1 A. Dona,3 H. Leuvenink,2 S. Fuggle,1 B. Kessler,1 C. Pugh,1 R. Ploeg.1

    1University of Oxford, Oxford, United Kingdom; 2University of Groningen, Groningen, Netherlands; 3University of Sydney, Sydney, Australia

    The pro-coagulatory and pro-inflammatory environment in donors after brain death (DBD) and warm ischemia in donors after circulatory death (DCD) can cause injury to target…
  • 2017 American Transplant Congress

    Effect of HLA-DQ Mismatch on Efficacy Outcomes and Renal Function in Kidney Transplant Recipients: Subanalysis from the ELEVATE Study.

    W. Arns,1 J. Cruzado,1 H. Holdaas,1 P. Lopez,2 P. Bernhardt,2 G. Bader,2 F. Claas,1 M. van der Giet,1 J. de Fijter.1

    1ELEVATE Study Group, Köln, Germany; 2Novartis Pharma AG, Basel, Switzerland

    Purpose: Human leukocyte antigen (HLA)-DQ mismatches are often associated with acute rejection, independent of mismatches at other loci. Previous analysis from the ELEVATE (NCT01114529) study…
  • 2017 American Transplant Congress

    Benefits of Mycophenolate Sodium Over Mycophenolate Mofetil in Renal Transplant Patients Carrying UGT1A9 Polymorphism.

    N. Calvo Romero, I. Perez-Flores, A. Shabaka, M. Moreno De La Higuera, B. Rodriguez-Cubillo, J. Delgado, M. Calvo, V. Lopez De La Manzanara, A. Sanchez-Fructuoso.

    Nephrologist, Hospital Clínico San Carlos, Madrid, Spain

    Aims: To analyze the differences in mycophenolic acid (MPA) pharmacokinetics and digestive side effects in renal transplant recipients on treatment with Mycophenolate mofetil (MMF) and…
  • 2017 American Transplant Congress

    Steroid Free Maintenance Immunosupression in Kidney Transplantation: Indiana University Experience.

    S. Hussain, T. Taber, A. Sharfuddin, M. Yaqub, W. Goggins, D. Mishler, O. Adebiyi.

    Renal Transplant, Indiana University School of Medicine, Indianapolis, IN

    Background: Steroid based maintenance Immunosuppression (IS) regimen is the standard protocol for many kidney transplant(tx) centers. However, concerns for chronic steroid impact on patients remains…
  • 2017 American Transplant Congress

    CMV and BK Virus Infections in Kidney Transplant Recipients Receiving an mTORi-Based Regimen versus a CNI-Based Regimen: A Systematic Review and Meta-Analysis.

    B. Tanios,1 S. Mallat,1 H. Itani,1 T. Lotfi,1 S. Gabardi,2 E. Akl,1 J. Azzi.2

    1Division of Nephrology, American University of Beirut Medical Center, Beirut, Lebanon; 2Renal Division, Harvard Medical School, Boston

    The objective of this systematic review is to compare the incidence of CMV and BK virus infections in kidney transplant recipients receiving an mTORi-based as…
  • 2017 American Transplant Congress

    Clinic-Based Medication Education Pilot Program.

    N. Sulejmani,1 H. Albanna,1 T. Rendulic,2 B. Summers,1 A. Jantz.1

    1Henry Ford Hospital, Detroit, MI; 2University of Kentucky, Lexington, KY

    Purpose: Adherence to medications is crucial for transplant patients as missing medications can result in increased risk of rejection and graft loss. Augmented education may…
  • 2017 American Transplant Congress

    Glucose Tolerance After Kideney Transplant Is Affected by Systemic Insulin Sensitivity Rather Than Usage of Tacrolimus.

    D. Iwami,1 A. Nakamura,2 K. Hotta,1 H. Sasaki,1 T. Hirose,1 H. Higuchi,1 Y. Takada,1 H. Miyoshi,2 N. Shinohara.1

    1Urology, Hokkaido University Hospital, Sapporo, Hokkaido, Japan; 2Internal Medicine II, Hokkaido University Hospital, Sapporo, Hokkaido, Japan

    Introduction and Objective: Tacrolimus and steroid can affect insulin secretion and insulin sensitivity, resulting in worsened glucose tolerance after kidney transplant (KTx). However, the effect…
  • 2017 American Transplant Congress

    mTOR Inhibitor and Low-Dose Tacrolimus in Pediatric Kidney Transplant (PKT): 9-Years Data of a Bi-Therapy Treatment.

    R. Vilalta, E. Lara, A. Madrid, M. Muñoz, S. Chocron, G. Ariceta.

    Pediatric Nephrology, Hosptal Vall d´Hebron, Barcelona, Spain

    INTRODUCTIONNephrotoxicity , serious infectious, or malignancy risk , curtails tacrolimus use in PKT . However, based on potential antiviral and antitumoral actions of mTOR inhibitor…
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