ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Utility of Electron Microscopy in Kidney Transplant Biopsies.

    J. Grodsky,1 R. Craver,1,2 I. Ashoor.2

    1LSUHSC, New Orleans, LA; 2Children's Hospital, New Orleans, LA

    Background: Banff 2013 criteria recommends performing ultra-structural studies with electron microscopy (EM) in most kidney transplant (KT) biopsies if the technology is available. We aimed…
  • 2017 American Transplant Congress

    Variables Associated with Liver Graft Utilization and 30-Day Failure: A Liver Graft Quality Index.

    J. Tang,1 M. Esfandiari,1 A. Zarrinpar.2

    1Statistics, University of California, Los Angeles, CA; 2Surgery, University of California, Los Angeles, CA

    The quantitative evaluation of liver graft quality remains one of the most understudied clinical problems in transplantation. A few scoring systems have been proposed, but…
  • 2017 American Transplant Congress

    WHO Group II Pulmonary Hypertension Is Associated with Decreased Survival in Patients Awaiting Liver Transplantation.

    H. Memon, J.-A. Guerra, B. Trachtenberg, J. Estep, A. Bhimaraj, I. Hussain, M. Park, H. Monsour, M. Ghobrial, A. Guha.

    Medicine, Houston Methodist Hospital, Houston, TX

    End stage liver disease (ESLD) patients with cirrhotic cardiomyopathy often have WHO Group II pulmonary hypertension (PH), characterized by pulmonary capillary wedge pressure (PCWP) >15…
  • 2017 American Transplant Congress

    Utility of Concomitant Biopsy in Simultaneous Pancreas Kidney Transplant Recipients in the Identification of Rejection of Pancreas and Kidney.

    C. Johnson, K. Johnson, B. Kaplan, M. Temkit, R. Heilman, S. Sukumaran Nair, H. Khamash, J. Huskey, G. Mour, H. Chakkera.

    Mayo Clinic Arizona, Phoenix, AZ

    Background: In simultaneous pancreas and kidney transplant (SPKTx) recipients, animal studies suggest concordant rejection rates of 88% (ref: Gruessner et al,1994). Limited information is available…
  • 2017 American Transplant Congress

    Elevated Serum Lipase Levels in Simultaneous Pancreas and Kidney Transplantation May Indicate Anti-HLA Donor Specific Antibody Response.

    B. Javaid, T. Raza, P. Abrams, S. Ghasemian, J. Moore, A. Gilbert, M. Grafals, J. Verbesey, M. Cooper.

    Kidney and Pancreas Transplant Program, MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Georgetown University School of Medicine, Washington, DC

    Background: Development of anti-HLA donor specific antibodies (DSAs) has been associated with inferior pancreas transplant outcomes. We analyzed data for pancreas and kidney transplant recipients…
  • 2017 American Transplant Congress

    Total Pancreatectomy and Islet Autotransplantation into the Liver of a Patient with Previous Hepatitis C Infection.

    A. Rajab,1 J. Buss,1 P. Hart,2 D. Conwell,2 S. Black,1 K. Washburn.1

    1Transplant Surgery, The Ohio State Wexner Medical Center, Columbus, OH; 2Internal Medicine, The Ohio State Wexner Medical Center, Columbus, OH

    Hepatic parenchymal disease such as hepatitis has been considered a relative contraindication to islet transplantation as the islets are infused into the liver. Islet transplantation…
  • 2017 American Transplant Congress

    10 Years of DTAC Experience with Kaposi's Sarcoma – Not Just Another PTLD!

    M. Nalesnik,1 M. Clark,2 S. Tlusty,2 M. Michaels,1 C. Wolfe.1

    1DTAC, Richmond; 2United Network for Organ Sharing, Richmond

    Background:Kaposi's Sarcoma (KS), a tumor derived from the oncogenic virus human herpesvirus-8 (HHV8) is strongly associated with immunodeficiencies. Classically seen with AIDS, it can also…
  • 2017 American Transplant Congress

    Expansion, Function and Clonotypic Analysis of Human Alloreactive Treg Stimulated with Different Dendritic Cell Populations or CD40L-Stimulated B Cells.

    H. Zhang,1 Y. Zhao,1 Q. Tang,3 A. Thomson.1,2

    1Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA; 2Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA; 3Department of Surgery, UCSF, San Francisco, CA

    Purpose:In order to establish a protocol to generate large numbers of human alloantigen-reactive regulatory T cells (arTreg) with potent allospecific suppressive capacity for therapeutic application,…
  • 2017 American Transplant Congress

    Functional Mystacial Pad Allograft Tolerance Induced and Maintained by Vascularized Bone Marrow Transplant.

    C.-H. Lin,1,2 M. Anggelia,1,2 C.-J. Wen,1 W.-Y. Chuang,3 H.-Y. Cheng,1 C.-H. Lin,1,2 G. Brandacher.4

    1Department of PRS, Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 2Chang Gung Medical College and Chang Gung University, Taoyuan, Taiwan; 3Department of Pathology, Chang Gung Memorial Hospital, Taoyuan, Taiwan; 4Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD

    Background: Accumulating findings indicate that vascularized bone marrow (VBM) transplantation plays a critical role to promote tolerance of vascularized composite allografts (VCA) without life-long immunosuppression.…
  • 2017 American Transplant Congress

    Experimental Study of Hepatocyte Proliferation Regulated by miR26a.

    J. Zhou, X. Yuan, W. Ju, X. Jiao, D. Wang, X. Zhu, X. He.

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China

    Objective To investigate mechanisms of regulation on hepatocyte proliferation by miRNAs. Methods Normal hepatocyte in ivtro was transfected with vectors harboring Ad5/anti-miR26a or Ad5/miR26a, and…
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