ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Differential Suppressive Effects of Costimulatory Blockade (CD28/B7), Anti-IL6R, Bruton's Tyrosine Kinase and Janus Kinase Inhibition on De Novo vs. Recall Alloantibody Responses: Are Combined Drug Therapy Approaches Desirable?

    I. Kim, G. Wu, N.-N. Chai, A. Klein, S. Jordan.

    Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

    Purpose: Preformed and de novo donor specific antibodies (DSA) contribute significantly to demise of allograft functions. There is no approved therapies for prevention or treatment…
  • 2017 American Transplant Congress

    Kidney Re-Transplantation (KRTx) from Donation After Cardiocirculatory Death (DCD)-Standard Criteria Donors (SCD).

    M. Khan, B. Alradawna, A. Farney, J. Rogers, G. Orlando, A. Reeves-Daniel, A. Palanisamy, M. Gautreaux, W. Doares, S. Kaczmorsky, R. Stratta.

    Transplant, Wake Forest Baptist Medical Center, Winston Salem, NC

    Donation after cardiac death (DCD) donor kidneys increase the organ pool but use in kidney retransplantation (KRTx) has been questioned due to higher rates of…
  • 2017 American Transplant Congress

    Ethnocultural Barriers to Pre-Emptive Kidney Transplantation: A Single Centre Retrospective Cohort Study.

    A. Bansal, M. Kwok, S. Cao, O. Famure, S. Kim, I. Mucsi.

    University Health Network, Toronto, ON, Canada

    BackgroundPre-emptive kidney transplant (PKT) may offer better outcomes compared to kidney transplant (KT) after starting dialysis. There is a well-documented disparity in access to PKT…
  • 2017 American Transplant Congress

    Health Literacy, Functional Status and Transplant Eligibility Among Adult Liver Transplant Candidates.

    M. Serper, K. Dwinnells, M. Wolf, K. Olthoff.

    University of Pennsylvania, Philadelphia; Northwestern University, Chicago

    Introduction/Objectives: Low health literacy is associated with poor self-care in chronic diseases, however, is understudied in liver transplantation (LT). Study objectives were to evaluate associations…
  • 2017 American Transplant Congress

    The Performance of Four Tools for the Prediction of Potential for Organ Donation After Cardiac Death in Neurocritical Patients: A Prospective, Multicenter, Observational Study.

    Z. Guo,1 G. Xu,1 P. Schroder,2 M. Manyalich,3 X. He,1 G. Chen.1

    1Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; 2Department of Surgery, Duke University Medical Center, Durham; 3Transplant Procurement Management-Donation & Transplantation institute Foundation, Barcelona, Spain

    Background Successful donation after circulatory death (DCD) requires identification of patients dieing within limited time after withdrawal of life-sustaining treatment (WLST). We aimed to compare…
  • 2017 American Transplant Congress

    In the Modern Era, Cytomegalovirus Does Not Appear to Increase Intimal Thickening After Heart Transplantation.

    D. Leong, B. Azarbal, J. Patel, M. Kittleson, L. Czer, T. Aintablian, D. Chang, D. Geft, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles

    Background: Cytomegalovirus (CMV) has been associated with the subsequent development of cardiac allograft vasculopathy (CAV) after heart transplantation. In the more recent era, CMV has…
  • 2017 American Transplant Congress

    Severe Tricuspid Regurgitation After Heart Transplantation: Does It Require Surgical Repair?

    J. Patel, M. Kittleson, L. Czer, T. Aintablian, R. Sharoff, R. Levine, A. Velleca, D. Ramzy, F. Esmailian, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles

    Background: Tricuspid regurgitation (TR) after heart transplantation is common. Causes for TR may be due to volume overload, flail tricuspid leaflet from endomyocardial biopsy, pulmonary…
  • 2017 American Transplant Congress

    Histone Methyltransferase EZH2 Was Involved in the Mechanism of let-7e Inhibition of TNF-α Expression.

    J. Huang,1,2,3 Y. Zhang,1,2,3 Q. Zhang,1,2,3 L. Gui,1,2,3 Y. Cai,1,2,3 X. Deng.1,2,3

    1Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; 2Guangdong Provincial International Cooperation Base of Science and Technology (Organ Transplantation), The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China; 3Institute of Immunology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China

    Inflammatory cytokines, such as TNF-α, play important roles in transplantation and infection. The expression of these inflammatory factors can be regulated by many kinds of…
  • 2017 American Transplant Congress

    Titers of Blood Group B Patients Using Non-A1 Reagent/Donor Cells for the Purpose of ABO Incompatible Kidney Transplantation.

    D. King, M. Aguilucho, M. Marchioni, B. Figueiredo, I. Okere, P. Rao.

    NJ Sharing Network, New Providence

    Background: Blood group B patients are eligible to receive offers from non-A1 or non-A1B kidney donors. Current practice in many institutions involves performing these titers…
  • 2017 American Transplant Congress

    Avascular Necrosis in Kidney Transplant Recipients: Recent Data from a Cohort Study.

    P. Perrin,1 R. Felten,2 S. Caillard,1 M. Schaeffer,3 B. Moulin,1 R.-M. Javier.2

    1Nephrology, Transplantation Department, University Hospital, Strasbourg, France; 2Rheumatology Department, University Hospital, Strasbourg, France; 3Public Health Department, University Hospital, Strasbourg, France

    Avascular osteonecrosis (AVN) is the most disabling bone complication after kidney transplantation (KT). Its incidence decreased from 15% to 4% after the introduction of cyclosporine…
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