ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    De Novo Donor-Specific Antibody Formation After Kidney Retransplant Is Associated with Specificity Against Class I.

    K. Atiemo,1 B. Ho,1 H. Bhagat,2 E. Lee,2,3 A. Daud,1 R. Kang,1 S. Montag,1,4 L. Zhao,1,4 J. Schwartz,2 D. Ladner.1

    1Northwestern University Transplant and Outcomes Research Collaborative (NUTORC), Chicago; 2Astellas Pharma Global Development, Northbrook; 3Now with UCB, Atlanta; 4Dept of Preventive Medicine, Northwestern University, Chicago

    Retransplant (RTx) patients are often sensitized due to donor-specific antibody (DSA) formation, with higher acute rejection rates during subsequent transplants vs patients without DSA. However,…
  • 2017 American Transplant Congress

    Long-Term Outcomes of Kidney Transplant Recipients with Primary Idiopathic Focal Segmental Glomerulosclerosis (FSGS).

    D. Khadzhynov, F. Halleck, L. Lehner, E. Schrezenmeier, K. Budde, O. Staeck.

    Nephrology, Charité Universitaetsmedizin, Berlin, Germany

    Introduction:Few data exists analyzing recurrence rates, treatment response and long-term outcomes in kidney transplant recipients (KTR) with primary FSGS.Methods: This retrospective observational study included 1218…
  • 2017 American Transplant Congress

    Alemtuzumab Induction Is Safe, and Permits the Avoidance of Steroids in the Majority of Renal Transplant Recipients.

    A. Seitz,1 M. Robb,2 N. Ahmad,1 A. McLean,3 D. Taube,3 R. Johnson,2 R. Baker.1

    1Renal Unit, St James's Hospital, Leeds, United Kingdom; 2Organ Donation and Transplantation Studies, NHS Blood and Transplant, Bristol, United Kingdom; 3West London Renal and Transplant, Hammersmith Hospital, London, United Kingdom

    IntroductionThe introduction of alemtuzumab into routine clinical use has been hindered by safety concerns surrounding its prolonged effect on the lymphoid compartment. Here we report…
  • 2017 American Transplant Congress

    Evaluation of Low Dose Valganciclovir for the Prevention of Cytomegalovirus in Liver Transplant Recipients.

    C. Payne,1 J. Melaragno,1 D. Hutchinson,1 T. Babu,2 P. Prasad,2,3 T. Dick.1

    1Pharmacy, University of Rochester Medical Center, Rochester, NY; 2Division of Infectious Diseases, University of Rochester Medical Center, Rochester, NY; 3Division of Pulmonary and Critical Care Medicine, University of Rochester Medical Center, Rochester, NY

    BACKGROUND: Cytomegalovirus (CMV) causes significant morbidity and mortality following orthotopic liver transplantation (OLT). Valganciclovir (VGCV) is used to prevent CMV, but at labeled doses can…
  • 2017 American Transplant Congress

    Relationship of Liver Extraction Times to Early Allograft Dysfunction and Post-Transplant Kidney Injury.

    D. Simpson, M. Gupta, C. McAllister, P. Porrett, D. Goldberg, M. Levine, K. Olthoff, A. Shaked, P. Abt.

    Hospital of the University of Pennsylvania, Philadelphia, PA

    Background: Donor extraction times for kidney allografts are associated with inferior kidney outcomes. We hypothesized that that longer donor liver extraction times would be associated…
  • 2017 American Transplant Congress

    Incidence and Outcomes of Re-Explorations in Living Donor Liver Transplantation.

    V. Varma, S. Sable, S. Kapoor, A. Chauhan, V. Kumaran.

    Hepato-Biliary-Pancreatic Surgery and Liver Transplantation, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, Maharashtra, India

    Introduction: Re-exploration in Living Donor Liver Transplantation(LDLT) is required in patients for various causes, bleeding being the commonest cause. The outcome of these patients is…
  • 2017 American Transplant Congress

    Age and Gender Disparities in Post-Lung Transplant Mortality.

    H. Maredia, M. Bowring, A. Massie, S. Oyetunji, C. Merlo, R. Higgins, D. Segev, E. Bush.

    JHU, Baltimore

    Gender, race, and age have been associated with health disparities, including in post-transplant outcomes. Given disparities in post-lung transplant outcomes are not well-understood, we assess…
  • 2017 American Transplant Congress

    Improving Vaccination Rates for Lung Transplant Candidates.

    M. Cortez,1 R. Bag,2 L. Potter.1

    1Pharmacy, The University of Chicago Medicine, Chicago, IL; 2Transplant Center, The University of Chicago Medicine, Chicago, IL

    In 2015, transplant pharmacists at the University of Chicago identified an opportunity to improve vaccination rates for transplant candidates. On 10/1/15, a pharmacist-led program was…
  • 2017 American Transplant Congress

    Variability in Tacrolimus Concentrations Across Pediatric Solid Organ Transplants.

    S. Min,1 T. Daljevic,1 O. Lee,1 M.-E. Alary,6 F. Murdoch,5 R. Parekh,1 V. Ng,1 D. Hebert,1 L. Hamiwka,2 T. Blydt-Hansen,3 V. Phan,4 P. Birk,3 U. Allen,1 S. Urschel,5 CNTRP POSITIVE Research Group, B. Foster,6 S. Mital.1

    1The Hospital for Sick Children, Toronto, Canada; 2Alberta Children's Hospital, Calgary, Canada; 3University of Winnipeg, Winnipeg, Canada; 4Université de Montréal, Motreal, Canada; 5Stollery Children's Hospital, Edmonton, Canada; 6McGill University, Montreal, Canada

    PURPOSE: We characterized the evolution of out-of-range tacrolimus (TAC) concentrations and associated factors during 1 year following a pediatric solid organ transplant (SOT).METHODS: Heart, kidney…
  • 2017 American Transplant Congress

    Distinctive Molecular Features of Antibody-Mediated versus T-Cell Mediated Rejection in Facial Transplantation.

    R. Lopdrup, T. Win, N. Murakami, J. Teague, A. Chandraker, G. Murphy, C. Lian, E. Bueno, B. Pomahac, R. Clark, L. Riella.

    Brigham and Women's Hospital, Boston, MA

    BackgroundA single case of antibody-mediated rejection in a clinical face transplant has been reported worldwide. The availability of repeated allograft biopsies from this patient allowed…
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