Am J Transplant, Volume 17, Suppl 3 Archives - Page 20 of 181 - ATC Abstracts

2017 American Transplant Congress
Immunosuppressive Role of Pancreas Derived Mesenchymal Stem Cells.
M. Kanak,¹ F. Kunnathodi,² M. Levy,^1,3 M. Lawrence,² B. Naziruddin.⁴
¹Transplant Surgery, Virginia Commonwealth University, Richmond, VA; ²Baylor Research Institute, Dallas, TX; ³Hume-Lee Transplant Center, VCU Health System, Richmond, VA; ⁴Simmons Transplant Institute, Baylor Scott and White Health, Dallas, TX
BackgroundThe Edmonton protocol revived islet transplantation therapy for Type-1 Diabetic patients. However, Long-term islet function still remains a challenge. Immunosuppression used after islet transplantation contributes…
2017 American Transplant Congress
Identification of Plasma Protein Biomarkers of Acute Renal Allograft Rejection.
M. Rossetti,¹ C. Fitzpatrick,¹ N. Harre,¹ Y. Zheng,¹ N. Mercer,² G. Sunga,¹ D. Gjertson,¹ E. Reed.¹
¹Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA; ²Department of Biostatistics, University of California Los Angeles, Los Angeles, CA
Background & Aim: Upon presentation of clinical symptoms, renal transplant recipients routinely undergo needle core biopsy to diagnose acute graft rejection. This procedure is invasive…
2017 American Transplant Congress
Mechanistic Insights by RNA Profiling on Rejecting Vascularized Composite Allotransplants.
H.-Y. Cheng,¹ S.-C. Liu,² C.-F. Lin,¹ L.-Y. Shih,³ F.-C. Wei.^1,2,3
¹Center for Vascularized Composite Allotransplantation, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan; ²College of Medicine, Chang Gung University, Taoyuan, Taiwan; ³Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan
Background: Detailed molecular changes associated with rejection to vascularized composite allotransplants (VCA) are not well understood. Materials and Methods: peripheral blood was drawn from the…
2017 American Transplant Congress
Renoprotective Effects of Carbon Monoxide–Releasing Molecule 3 in Ischemia Reperfusion Injury and Cisplatin-Induced Toxicity.
Y. Yoon,¹ H. Lee,¹ K. Huh,² M. Kim,² S. Kim,² Y. Kim,² W. Han.¹
¹Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea; ²Transplantation Surgery, Research Institute for Transplantation, Yonsei University College of Medicine, Seoul, Republic of Korea
Background: We investigated the effects of a soluble carbon monoxide–releasing molecule (CORM) in cisplatin-induced cytotoxicity and ischemia reperfusion injury (IRI) in vitro.Methods: The effects of…
2017 American Transplant Congress
Comparison of Long Term Survival Outcomes for Everolimus (EVR) vs. Mycophenolic Acid (MPA) Immunosuppressive Regimens Post Kidney Transplant.
D. Cibrik,¹ W. Irish,² K. McCague,³ D. Patel,³ H. Tedesco.⁴
¹University of Michigan, Ann Arbor, MI; ²CTI Clinical Trial and Consulting Services, Raleigh, NC; ³Novartis Pharmaceuticals Corporation, East Hanover, NJ; ⁴Hospital do Rim-Escola Paulista de Medicina UNIFESP, Sao Paulo, Brazil
In the US, MPA in combination with calcineurin inhibitors (CNI, tacrolimus [TAC] or cyclosporine A [CsA]) is the most commonly used maintenance immunosuppressive therapy post…
2017 American Transplant Congress
Determinants of Successful Use of Sirolimus in Renal Transplantation.
M. Naik,¹ W. Gwinner,² W. Arns,³ E. Basic,¹⁰ K. Budde,¹ F. Diekmann,⁴ M. Fischereder,⁵ J. Goßmann,⁶ K. Heller,⁷ N. Heyne,⁸ J.-S. Jürgensen,¹ C. Morath,⁹ U. Riester.¹⁰
¹GSSG, Berlin, Germany; ²GSSG, Hannover, Germany; ³GSSG, Köln, Germany; ⁴GSSG, Barcelona, Spain; ⁵GSSG, München, Germany; ⁶GSSG, Frankfurt, Germany; ⁷GSSG, Erlangen, Germany; ⁸GSSG, Tübingen, Germany; ⁹GSSG, Heidelberg, Germany; ¹⁰GSSG - Pfizer, Berlin, Germany
Sirolimus (SLR) is an established component in the immunosuppressive treatment after renal transplantation.The side effects of SLR differ from other immunosuppressants and may limit its…
2017 American Transplant Congress
Effect of Everolimus on the Cardiac Function in Kidney Transplant Recipients.
K. Tsujimura,¹ M. Ota,¹ H. Ishida,² K. Tanabe.²
¹Surgery, Tomishiro Central Hospital, Tomishiro-shi, Okinawa, Japan; ²Urology, Kidney Center, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan
PURPOSE: In this study, we evaluated the effect of everolimus (EVR), one of the mammalian targets of rapamycin on cardiac function in kidney transplant recipients.METHODS:We…
2017 American Transplant Congress
Soluble Human Leukocyte Antigen-G Levels and Prolonged Allograft Survival: A Demographic Analysis.
C. Callaway,¹ A. Ajith,² V. Portik-Dobos,² P. Best,³ C. Zayas,³ R. Kapoor,³ A. Horuzsko,² L. Mulloy.³
¹Medical College of Georgia, Augusta University, Augusta, GA; ²Georgia Cancer Center, Augusta University, Augusta, GA; ³Section of Nephrology, Department of Medicine, Augusta University, Augusta, GA
Human leukocyte antigen-G (HLA-G) is a tolerogenic protein shown to contribute to allograft survival. Dimerized, soluble HLA-G (sHLA-Gd) has been shown to significantly prolong allograft…
2017 American Transplant Congress
Everolimus Reduces Carotid Intima-Media Thickness in Renal Transplant Recipients After One Year: Randomized Controlled Trial.
P. Garcia, H. Takase, H. Nga, M. Contti, J. Hueb, L. Morales-Buenrostro.
Internal Medicine, Botucatu Medical School - Universidade Estadual Paulista, Botucatu, São Paulo, Brazil
Cardiovascular disease remains the commonest cause of death in kidney transplant recipients. Although some studies suggest that Mammalian target of rapamycin (mTOR) inhibitors may reduce…
2017 American Transplant Congress
The Clinical Significance of Red Cell Distribution Width (RDW) in Kidney Transplant Recipients.
S. Park,¹ J. Ha,¹ Y. Kim,¹ H. Lee,¹ Y. Kim,¹ C. Lim,¹ I. Jung,¹ D.-J. Han,² S.-K. Park,² Y. Kim,² J. Lee.¹
¹Seoul National University College of Medicine, Seoul, Korea; ²Asan Medican Center, Seoul, Korea
Background Increased red cell distribution width (RDW) has been known to be associated with worse prognosis in various populations. Although the levels of RDW are…