Am J Transplant, Volume 17, Suppl 3 Archives - Page 181 of 181 - ATC Abstracts

2017 American Transplant Congress
Contributing Factors and Impact of Microbial Contamination in Human Islet Isolation and Transplantation.
R. Meier, D. Andrey, N. Niclauss, P. Sun, C. van Delden, B. Bedat, S. Demuylder-Mischler, S. Borot, P.-Y. Benhamou, A. Wojtusciszyn, N. Pernin, Y. Muller, D. Bosco, T. Berney.
Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospitals and Medical School, Geneva, Switzerland; Division of Infectious Diseases, Department of Medical Specialties, Geneva University Hospitals and Medical School, Geneva, Switzerland
BackgroundThe microbiological safety of islet preparations is of paramount importance. Preservation medium contamination is frequent and its impact on islet yield and function remains unclear.MethodsAll…
2017 American Transplant Congress
Impact of Caregiver on 30 Day Readmission After Lung Transplant.
T. Coco, C. Keller, F. Alvarez, D. Erasmus, J. Mallea.
Department of Transplantation, Mayo Clinic Florida, Jacksonville, FL
The type of primary caregiver has been associated with long-term outcomes after lung transplantation. There is no data on the impact of caregiver associated with…
2017 American Transplant Congress
A-Antigen (Ag)-Specific Tolerance Following A-Ag Administration to Infant Mice.
B. Motyka,¹ Y. Wang,¹ B. Lamarche,¹ I. Adam,¹ J. Pearcey,¹ K. Tao,¹ C. Cairo,² P. Cowan,³ L. West.¹
¹Dept Pediatrics, Alberta Transplant Institute, Canadian National Transplant Research Program, University of Alberta, Edmonton, Canada; ²Dept Chemistry, Alberta Glycomics Centre, University of Alberta, Edmonton, Canada; ³Immunology Research Centre, St Vincent's Hospital, University of Melbourne, Melbourne, Australia
Purpose: In contrast to adults, ABO-incompatible heart transplantation (ABOi HTx) can safely be performed in infants due to absent/low levels of anti-A/B antibodies (Ab). Tolerance…
2017 American Transplant Congress
Which Tr1 Is Better for Transplant Tolerance Induction: Comparing the Tr1 Generated by IL-27 or TGF-βplus IL-27.
G. Gu, H. Hang, Q. Xia.
Department of Hepatic Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China
IL-10 producing T cells (Tr1) are important for the transplant tolerance induction. However, Tr1 can be induced in two methods: IL-27 or TGF-βplus IL-27. We…
2017 American Transplant Congress
Exosomes Containing IL35 Are Secreted by Donor-Specific Regulatory T Cells and Cause Linked-Suppression.
Y. Tomita,¹ W. Bracamonte-Baran,¹ E. Jankowska-Gan,¹ Q. Zhang,² D. Vignali,² W. Burlingham.¹
¹Surgery, Transplant Division, University of Wisconsin-Madison, Madison, WI; ²Immunology, University of Pittsburgh, Pittsburgh
Introduction: We previously reported that donor specific splenocytes transfusion (DST) plus anti-CD40L costimulatory blockade treatment causes allo-specific regulation approximately 5 weeks after the tolerization. The…
2017 American Transplant Congress
Confirmation of the Safety of Cryopreserved Human Cord Blood Derived Di-Chimeric Cells in the NSG Mouse Model.
J. Cwykiel, N. Filipek, E. Szilagyi, E. Tfaily, M. Siemionow.
Orthopaedics, University of Illinois at Chicago, Chicago, IL
Background: Cell therapies are a promising approach for tolerance induction in Vascularized Composite Allotransplantation (VCA). Thus, we have developed a new supportive therapy of ex…