ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    Alcohol-Induced Hepatic Cirrhosis Is Rising Among Young Adults.

    C. Kling,1 J. Perkins,1 D. Donovan,2 R. Carithers,3 L. Sibulesky.1

    1Division of Transplant Surgery, University of Washington, Seattle, WA; 2Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA; 3Division of Hepatology, University of Washington, Seattle, WA

    Background: Alcoholic cirrhosis is a common indication for liver transplantation. Recent population studies have shown no change in the overall prevalence of alcohol use, but…
  • 2017 American Transplant Congress

    Myeloid-Derived Suppressor Cells (MDSC) Accumulate in Intestinal Transplant (IT) Recipients (rc) and Suppress Recipient T-Cell (T) Response Against Donor Antigen.

    S. Okano,1 D. Kish,2 K. Keslar,2 W. Baldwin,2 R. Fairchild,1 C. Miller,1 K. Abu-Elmagd,1 A. Khanna,1 M. Fujiki,1 J. Fung,1 G. Costa,1 K. Hashimoto.1

    1Transplant Center, Dept. General Surgery, Digestive Disease & Surgery Institute, Cleveland Clinic, Cleveland, OH; 2Dept. Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH

    [Introduction] Recent advances of immunosuppressive regimens have decreased rejection rate and improved rc survival of IT. MDSC are potent immature myeloid cells capable of suppressing…
  • 2017 American Transplant Congress

    Prolonged Survival with Co-Stimulatory Blockade Based Immunosuppression in Pig-to-Primate Liver Xenotransplantation.

    J. Shah, M. Patel, N. Elias, I. Rosales, N. Navarro-Alvarez, M. Hertl, A. Cosimi, R. Colvin, J. Markmann, D. Sachs, P. Vagefi.

    Massachusetts General Hospital, Boston, MA

    Background: Since the first attempt in 1968, survival following pig-to-baboon liver xenotransplantation (LXT) has been limited to <9-days due to a lethal coagulopathy. To improve…
  • 2017 American Transplant Congress

    Higher Mortality Among Candidates Who Refused Increased-Infectious Risk Kidney Offers.

    M. Bowring, L. Kucirka, A. Massie, C. Holscher, D. Segev.

    JHU, Baltimore

    Increased infectious risk donors (IRD) are younger and healthier than most deceased donors, but IRD kidneys are discarded at higher rates despite potential benefit to…
  • 2017 American Transplant Congress

    The New Kidney Allocation System in France Meets it's Targets: Improving Age and HLA DR-QD Matching for Young Adults.

    C. Jacquelinet, B. Audry, F. Bayer, M. Macher.

    Direction Medicale et Scientifique, Agence de la Biomedecine, Saint-Denis, France

    A new KAS was implemented in France as of February 2015, resulting from an intensive 3 yrs-simulation work in interaction with KTx advisory committee and…
  • 2017 American Transplant Congress

    Long-Term Outcomes After Liver Transplantation (tx) with Everolimus (EVR) and Mycophenolic Acid (MPA) in a Calcineurin Inhibitor-Free Regimen: The CERTITUDE Trial.

    F. Saliba,1 C. Duvoux,2 S. Dharancy,3 J. Dumortier,4 Y. Calmus,5 F. Di Giambattista,6 F. Conti.5

    1AP-HP Hôpital Paul Brousse, Villejuif, France; 2AP-HP Hôpital Henri Mondor, Créteil, France; 3CHRU de Lille, Lille, France; 4Hôpital Edouard Herriot, Lyon, France; 5AP-HP Hôpital Pitié Salpêtrière, Paris, France; 6Novartis Pharma SAS, Rueil-Malmaison, France

    Background. Long-term outcomes under EVR with MPA and no calcineurin inhibitor are undocumented after liver tx.Methods. CERTITUDE is a prospective, multicenter, observational study of liver…
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