Am J Transplant, Volume 17, Suppl 3 Archives - Page 181 of 181 - ATC Abstracts

2017 American Transplant Congress
Assessment of Simple Indices Based on a Single Fasting Blood Sample in Search for an Optimal Tool to Estimate Beta Cell Function After Islet Transplantation.
J. Golebiewska,¹ J. Solomina,² E. Konsur,² K. Cieply,² L. Basto,² A. Kotukhov,² K. Golab,² C. Thomas,³ A. Debska-Slizien,¹ P. Witkowski.²
¹Department of Nephrology, Medical University of Gdansk, Gdansk, Poland; ²Departemt of Surgery, University of Chicago, Chicago; ³Department of Medicine, University of Chicago, Chicago
Background:Precise yet logistically feasible evaluation of beta-cell function is extremely important after islet allotransplantation. We investigated the utility and possible limitations of indices using only…
2017 American Transplant Congress
Donor Recipient Matching Based on HLA Epitopes Improves Outcome in Kidney Transplant Recipients.
O. Staeck,¹ M. Niemann,³ F. Halleck,¹ D. Khadzhynov,¹ C. Schönemann,² P. Reinke,¹ E. Spierings,⁴ K. Budde,¹ N. Lachmann.²
¹Nephrology, Charité Universitaetsmedizin, Berlin, Germany; ²HLA Laboratory, Charité Universitaetsmedizin, Berlin, Germany; ³PIRCHE, Berlin, Germany; ⁴Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands
Background: HLA mismatches of the donor and recipient causing de novo donor-specific HLA antibodies (dnDSA) are a risk factor for immunologic complications and poor graft…
2017 American Transplant Congress
Gut Microbial Metabolite Improves Function and Prolongs Kidney Allograft Survival in Mice.
H. Wu,^1,2 T. Kwan,¹ Y. Loh,¹ X. Chen,¹ L. Macia,^2,3 S. Alexander,^2,4 S. Chadban.^1,2
¹Kidney Node Laboratory, The Charles Perkins Centre and Renal Medicine, Sydney Medical School and Royal Prince Alfred Hospital, Sydney, Australia; ²University of Sydney, Sydney, Australia; ³Nutritional Immunometabolism Lab, The Charles Perkins Centre, Sydney Medical School, Sydney, Australia; ⁴Nephrology Department, The Children Hospital at Westmead, Sydney, Australia
To determine the impact of dietary administration of the gut microbial metabolite sodium acetate (SA) on kidney rejection and survival in a fully MHC-mismatched murine…
2017 American Transplant Congress
Effect of Preformed Donor-Specific Antibodies in Intestine/Multivisceral Transplantation.
M. Safwan,¹ M. Rizzari,¹ K. Collins,¹ A. Yoshida,¹ S. Skorupski,² O. Fagoaga,² M. Abouljoud,¹ S. Nagai.¹
¹Divison of Transplant and Hepatobiliary Surgery, Henry Ford Transplant Institute, Detroit, MI; ²Transplant Immunology, Henry Ford Hospital, Detroit, MI
Aim: To analyze the effect of preformed donor-specific antibodies (DSA) in intestine/multivisceral transplantation patients.Methods: Retrospective review of preformed and de novo DSAs of all intestine/multivisceral…
2017 American Transplant Congress
CD28 Directed Immunotherapy Is More Potent Than Belatacept in a Nonhuman Primate Xenotransplant Model.
S. Kim,¹ L. Higginbotham,¹ D. Mathews,¹ C. Breeden,¹ A. Stephenson,¹ C. Larsen,¹ M. Ford,¹ J. Tector,² A. Adams.¹
¹Emory Transplant Center, Emory University, Atlanta, GA; ²University of Alabama Birmingham, Birmingham, AL
Introduction. Xenotransplantation may alleviate the organ shortage, yet experimental renal xenotransplantation has met limited success. T cell-mediated damage remains a critical problem. Our group has…
2017 American Transplant Congress
How to Improve Pre-Kidney Transplant Education for Hispanics: Preferences and Perceptions of Northwestern Memorial Hospital's Hispanic Transplant Program.
H. Gomez, E. Malagon-Blackwell, J. Caicedo.
The Comprehensive Transplantation Center, Northwestern University Feinberg School of Medicine, Chicago, IL
Context: Pre-Transplant educational sessions improve access to transplantation. Currently, however, there is lack of culturally competent approaches to improve living kidney donation for Hispanics Americans.…