Am J Transplant, Volume 17, Suppl 3 Archives - Page 181 of 181 - ATC Abstracts

2017 American Transplant Congress
Donor-Derived Nonclassical Monocytes Produce MIP-2 to Recruit Recipient Neutrophils and Cause Ischemia Reperfusion Injury After Lung Transplant.
S. Chiu,¹ Z. Zheng,¹ M. Akbarpour,¹ R. Fernandez,¹ A. McQuattie-Pimentel,¹ P. Reyfman,¹ K. Anekalla,¹ D. Kreisel,² H. Perlman,¹ G. Budinger,¹ A. Misharin,¹ A. Bharat.¹
¹Northwestern University, Chicago; ²Washington University, St Louis
Purpose: Primary graft dysfunction (PGD), the primary cause of early mortality after lung transplant, is mediated by neutrophils. However, neutrophil depletion may not be clinically…
2017 American Transplant Congress
Blood and Biopsy Genomic Signatures of Acute Rejection in Liver Transplant Recipients.
J. Levitsky,¹ T. Whisenant,² S. Kurian,² S. Rao,¹ A. Demetris,³ M. Abecassis.¹
¹Northwestern, Chicago; ²The Scripps Research Institute, San Diego; ³University of Pittsburgh, Pittsburgh
Background: Biomarker profiles diagnostic of acute rejection (AR) could enhance the diagnosis and management of liver transplant (LT) recipients. Our aim was to identify diagnostic…
2017 American Transplant Congress
Complement Binding Activity (C3d, C1q) of De Novo Donor-Specific HLA Antibody Is Associated with Increased Risk of Antibody-Mediated Rejection in Non-Sensitized Kidney Transplant Recipients.
H. Lee,¹ E. Han,¹ A.-R. Choi,¹ K. Park,² J. Ryu,² B. Chung,³ C. Yang,³ E.-J. Oh.¹
¹Laboratory Medicine, The Catholic University of Korea, Seoul, South Korea (KOR), Korea; ²Biomedical Science, Graduate School, The Catholic University of Korea, Seoul, South Korea (KOR), Korea; ³Division of Nephrology, Department of Internal Medicine, The Catholic University of Korea, Seoul, South Korea (KOR), Korea
Despite advances in therapeutic strategies and medicine, antibody mediated rejection (AMR) is a leading cause of kidney graft loss. The complement binding activity of donor-specific…
2017 American Transplant Congress
Comparison Between IgG, C1q and C3d Single Antigen Bead Assays in Detecting Class I Complement-Binding Anti-HLA Antibodies.
M. Moreno Gonzales,¹ D. Mitema,² B. Smith,³ C. Schinstock,³ M. Stegall,³ M. Gandhi.³
¹Servicio de Cirugía General, Clínica Anglo Americana, Lima, Peru; ²Division of Nephrology, Mississippi Baptist Medical Center, Jackson, MS; ³Transplant Center, Mayo Clinic, Rochester, MN
Introduction. Donor specific antibodies (DSA) are associated with an increased risk of chronic antibody mediated rejection (CAMR). DSA characterization by single antigen bead (SAB) assays…
2017 American Transplant Congress
PTEN Inhibition in MSC Upregulates PD-L1 and Enhances Their Immunomodulatory Capacity Prolonging Skin Allograft Survival.
M. Climov, M. Uehara, Z. Solhjou, H. Matsumine, N. Bouyani, E. Kefaloyianni, B. Basmani, V. Kasinath, G. Giatsidis, D. Orgill, R. Abdi.
Brigham and Women's Hospital, Boston, MA
Due to lack of autologous and donor site morbidity, there is a distinct clinical need to increase the utility of skin allografts by improving their…
2017 American Transplant Congress
Effect of Induction Therapy in ABO Incompatible Living-Donor Kidney Transplantation: A Single Center Experience.
L. Lanfranco, L. Esposito, A. Del Bello, O. Cointault, A. Allal, L. Rostaing, N. Kamar.
Department of Nephrology and Organ Transplantation, Toulouse University Hospital, Toulouse, France
Due to the shortage in organs, ABO incompatible (ABOi) living-donor kidney transplantation (LDKT) was developed. Herein, we report on our single center experience and assess…