Am J Transplant, Volume 17, Suppl 3 Archives - Page 181 of 181 - ATC Abstracts

2017 American Transplant Congress
IL-3 Contributes to Development of Basophil-Triggered Cardiac Allograft Fibrosis Development.
G. Schiechl-Brachner,¹ M. Rodriguez Gomez,¹ K. Renner,¹ S. Buchtler,¹ K. Schmidbauer,¹ D. Halbritter,¹ S. Neumayer,¹ Y. Talke,¹ H. Bruehl,² M. Mack.¹
¹Department of Internal Medicine II, University Hospital / Medical Center, Regensburg, Germany; ²Department of Internal Medicine I, University Hospital / Medical Center, Regensburg, Germany
Introduction: Organ fibrosis and vasculopathy are major causes of chronic cardiac allograft failure. Resident (donor-derived) fibroblasts are thought to be mainly responsible for excessive production…
2017 American Transplant Congress
CD4 T Cells and Co-Engagement with Foreign Protein Are Required in Antibody Response to Non-Self Blood Group A-Antigen.
I. Adam, B. Motyka, L. West.
Micro & Immunology, ATI, CNTRP, University of Alberta, Edmonton, AB, Canada; Pediatrics, ATI, CNTRP, University of Alberta, Edmonton, AB, Canada; Pediatrics, Surgerey, and Immunology, ATI, CNTRP, University of Alberta, Edmonton, AB, Canada
Background: ABO-incompatible heart transplantation (ABOi HTx) is safe during infancy and allows increased donor access. B-cell tolerance develops to donor A/B-antigen(s) (Ag) after ABOi HTx…
2017 American Transplant Congress
Molecular Classifier of Antibody-Mediated Rejection Is a Better Predictor of Histologic Rejection Than a Corresponding Transcript Set and Is Further Improved When Combined with Classifiers of Rejection Syndromes.
K. Famulski, P. Halloran.
University of Alberta, Edmonton, AB, Canada
Molecular and histologic changes in graft rejection are not completely specific, often being induced by injuries and other diseases. We examined various methods for using…
2017 American Transplant Congress
IVIG + Rituximab as Desensitization Agents to Reduce Donor Specific Antibodies and Improve Transplant Rates in Highly Hla Sensitized (HS) Awaiting Deceased Donor Kidney Transplantation.
R. Najjar, E. Huang, A. Vo, J. Cho, S. Louis, A. Hang, A. Peng, S. Jordan.
Medicine, Cedars-Sinai Medical Center, Los Angeles, CA
Background: HS patients are at risk for development of donor specific antibodies (DSA) and the persistence of DSA is associated with poor graft outcomes. Rituximab,…
2017 American Transplant Congress
Clostridium difficile Infection in Intestinal Transplant Recipients.
V. Goldenberg,¹ A. Berbel,² J. Camargo,¹ J. Simkins.¹
¹Medicine, Infectious Diseases, University of Miami Miller School of Medicine, Miami, FL; ²Medicine, University of Miami Miller School of Medicine, Miami, FL
Background: Clostridium difficile infection (CDI) data in intestinal transplant (ITx) recipients is lacking. This study was performed to evaluate prevalence, risk factors, treatments and outcomes…
2017 American Transplant Congress
MicroRNAs and Long Non-Coding RNAs as Potential Novel Biomarkers in Transplanted Patients with Candida Infection.
A. Yang,¹ C. Zhou,² D. Li,³ W. Ju,¹ Z. Guo,¹ L. Wu,¹ A. Hu,¹ Y. Ma,¹ D. Wang,¹ X. Zhu,¹ X. He.¹
¹Organ Transplantation Center, The First Affiliated Hospital of Sun Yat -sen University, Guangzhou, Guangdong, China; ²Gastroenterology Unit, Massachusetts General Hospital, Boston, MA; ³Ophthalmology, Schepens Research Institute, Boston, MA
There is an urgent need to develop sensitive and specific biomarkers for the early diagnosis of candida infection in transplanted patients. miRNAs and lncRNAs are…