Am J Transplant, Volume 17, Suppl 3 Archives - Page 181 of 181 - ATC Abstracts

2017 American Transplant Congress
Neuropeptide PACAP Prevents Hepatocyte Damage by Promoting Yes-Associated Protein (YAP) in Mouse Liver Ischemia/Reperfusion Injury.
Y. Liu,^1,2 C. Zhang,^1,3 R. Busuttil,¹ J. Kupiec-Weglinski,¹ Q. Xia,^1,2 H. Ji.¹
¹Department of Surgery, Dumont-UCLA Transplant Center, Los Angeles, CA; ²Liver Surgery, Ren Ji Hospital, Shanghai Jiao Tong University, Shanghai, China; ³Liver Surgery, 1st Affiliated Hospital, Zhejiang University, Hangzhou, China
Background: Yes-associated protein (YAP), a regulator of cellular anti-oxidation and regeneration, drives cell proliferation and promotes survival. We have previously demonstrated that neuropeptide pituitary adenylate…
2017 American Transplant Congress
Everolimus Does Not Increase Risk of Delayed Graft Function or Prolong Duration of Dialysis in Renal Transplantation.
F. Shihab,¹ Y. Qazi,² S. Mulgaonkar,³ K. McCague,⁴ D. Patel,⁴ V. Peddi,⁵ D. Shaffer.⁶
¹Univ of Utah, Salt Lake City; ²Univ of Southern California, Los Angeles; ³Barnabas Health, West Orange; ⁴Novartis, East Hanover; ⁵California Pacific Medical Center, San Francisco; ⁶Vanderbilt Univ Medical Center, Nashville
US92 (NCT01025817) is a phase III, 12 month, open-label, randomized study comparing everolimus (EVR) plus low-dose tacrolimus (LTac) vs. mycophenolate mofetil (MMF) with standard-dose tacrolimus…
2017 American Transplant Congress
Alemtuzumab Induction and Belatacept Maintenance in Marginal Pathology Renal Allografts.
T. Sparkes, B. Ravichandran, O. Opara, R. Ugarte, J. Bromberg, R. Barth.
University of Maryland, Baltimore
Background: The potential for improved outcomes with CNI avoidance may be important for kidneys with an increased likelihood of impaired graft function. We performed a…
2017 American Transplant Congress
Systemic Meta-Analysis: Is Early Conversion to mTOR Inhibitors Represent a Suitable Choice in Renal Transplant Recipients?
K. Jayant,¹ I. Reccia,² J. Walton,¹ A. Sharma,³ A. Halawa.¹
¹Faculty of Health and Sciences, Institute of Learning and Teaching, University of Liverpool, Liverpool, United Kingdom; ²Department of Hepato-Pancreato-Biliary Surgery (HPB), Hammersmith Hospital, Imperial College, London, United Kingdom; ³Sheffield Teaching Hospitals, Sheffield Teaching Hospitals, Sheffield, United Kingdom
Aim: This meta-analysis focuses on the current evidence of renal graft functioning and graft survival following early conversion to mTOR inhibitors with or without CNI…
2017 American Transplant Congress
Risks Associated with Recombinant IL2 Therapy in Renal Transplantation.
M. McGrath, S. Tripathi, A. Chandraker.
Brigham and Women's Hospital, Boston
Regulatory T cells are critical to allograft survival. We report a pilot study of safety and tolerability of low dose recombinant IL2 (rIL2), 1x106 units/m2/day…
2017 American Transplant Congress
The Effect of Histological Isolated Endarteritis and Solid Endoarteritis Combined with CD20 Positive B Cell Infiltration Appeared in Acute Cellular Rejection on Kidney Allograft Survival.
R. Wang, Y. Jiang, J. Wu, W. Peng, H. Huang, J. Chen.
Kidney Disease Center, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hanghzou, Zhejiang, China
BackgroundEndarteritis post renal transplantation is regarded as T-cell mediated acute rejection by Banff classification. Recently, results from DNA microarrays suggested that endovasculitis did not represent…