2017 American Transplant Congress
Split Liver Ex-situ Oxygenated Machine Perfusion: A Novel Approach to Organ Preservation and Treatment.
Ex-situ machine perfusion (MP) is a promising method to improve organ viability prior to transplantation and is being used in various clinical trials worldwide. However,…2017 American Transplant Congress
Immunosuppression (IS) Withdrawal (ISW) After ATG and Rituximab in Kidney Transplant Recipients (KTR): RESTARRT Early Results (NCT01318915).
Growing evidence implicates B cells in transplant tolerance. RESTARRT is a 6-center ISW study in adult living-related-donor KTR receiving ATG induction and rituximab with a…2017 American Transplant Congress
Once-Daily versus Twice-Daily Tacrolimus in Living Kidney Transplantation: A Multicenter, Parallel Group, Open-Label, 5-Year, Randomized Non-Inferiority Trial.
Background:Tacrolimus (TAC)-based induction therapy appears to be the standard immunosuppressive regimen for most kidney transplantation recipients (KTRs). TAC is available as a twice-daily (TAC-BID) and…2017 American Transplant Congress
Efficacy of Calcineurin Inhibitors Transferring to Rapamycin in Live Kidney Transplantation from Old Donors to Young Recipients.
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Background Calcineurin inhibitor(CNI) nephrotoxicity is one of the major reasons for chronic allograft injury in live kidney transplantation from old donors to young recipients. Therefore…2017 American Transplant Congress
Tacrolimus and Mycophenolate Exposure and Subclinical Tubulo-Interstitial Inflammation in Low Immunological Risk Renal Transplants.
The aim is to evaluate the relationship between maintenance immunosuppression, subclinical inflammation (i-score plus t-score) and interstitial fibrosis/tubular atrophy (IF/TA) (ci-score plus ct-score) in paired…2017 American Transplant Congress
Change in QTC Interval After Kidney Transplant.
Houston Methodist Hospital, Houston, TX
Cardiovascular (CV) disease is the leading cause of mortality in ESRD patients. A prolonged QTc interval on EKG is a predictor of adverse CV outcomes.…2017 American Transplant Congress
Impact of Six-Month Surveillance Biopsies and Monitoring in Pediatric Renal Transplant Recipients.
Purpose: Evaluate the utility of surveillance biopsies and monitoring 6 months post-transplant.Methods: A retrospective single center chart review of pediatric renal transplant recipients from 01/2011–10/2015…2017 American Transplant Congress
Importance of HLA-DR Expression in Pediatric Renal Transplant Biopsies.
Medical University of South Carolina, Charleston
ObjectiveTo determine which types of injuries in pediatric kidney transplant patients were associated with HLA-DR expression.Design/MethodsA retrospective chart review was conducted of children receiving a…2017 American Transplant Congress
A UNOS Database Analysis of Patient Outcomes from Kidney Alone versus Simultaneous Kidney Liver Transplants Utilizing Matched Donor Pairs.
Surgery - Division of Transplantation, University of Wisconsin - Madison, Madison, WI
Introduction: Renal grafts used in simultaneous kidney liver (SLK) transplants are allocated by arbitrary clinical criteria without entering the kidney allocation algorithm. The goal of…2017 American Transplant Congress
Subclinical Histologic Findings Are Observed in 25% of Stable Adult Liver Transplant Recipients (ALTRs) Screened for Immunosuppression Withdrawal (ISW): OPTIMAL (NCT02533180).
OPTIMAL is a 6-center ISW study in non-autoimmune, non-HCV ALTRs ≥3 yrs post-transplant (tx). Studies have shown a correlation between portal inflammation associated with tissue…
American Transplant Congress abstracts