ATC Abstracts

American Transplant Congress abstracts

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  • 2017 American Transplant Congress

    DNA Hypermethylation Caused by Ischemia in Kidney Transplants Predicts Future Chronic Injury to the Allograft.

    L. Heylen,1,2,3,4 B. Thienpont,3,4 M. Naesens,1,2 J. Depreeuw,3,4 P. Busschaert,3,4 D. Kuypers,1,2 I. Jochmans,2,5 D. Monbaliu,2,5 J. Pirenne,2,5 D. Lambrechts,3,4 B. Sprangers.1,2

    1Nephrology, University Hospitals Leuven, Leuven, Belgium; 2Microbiology and Immunology, KU Leuven, Leuven, Belgium; 3Oncology, KU Leuven, Leuven, Belgium; 4VIB, Leuven, Belgium; 5Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium

    Study Purpose: DNA demethylation results from hydroxymethylation and is inhibited by hypoxia. We investigated whether ischemia during kidney transplantation induces DNA methylation changes of the…
  • 2017 American Transplant Congress

    Effect of Blood Pressure Just Before Release of the Vascular Clamps on the Renal Function of Kidney Transplantation Recipients: A Retrospective Study.

    K. Tsujimura,1 M. Ota,1 H. Ishida,2 K. Tanabe.2

    1Surgery, Tomishiro Central Hospital, Tomishiro-shi, Okinawa, Japan; 2Urology, Tokyo Women's Medical University, Shinjuku-ku, Tokyo, Japan

    OBJECTIVE: To assess the effect of blood pressure just before release of the vascular clamps on the renal function of kidney transplantation (KTx) recipients.METHODS: We…
  • 2017 American Transplant Congress

    Acthar in Recurrent Focal Segmental Glomerular Sclerosis After Kidney Transplantation.

    T. Alhamad,1 J. Dieck,2 V. Vujjini,2 B. Kanawati,1 D. Brennan,1 N. Alachkar.2

    1Washington University in St. Louis, St. Louis; 2Johns Hopkins University, Baltimore

    Treatment of Recurrent focal segmental glomerular sclerosis (FSGS) after kidney transplantation is challenging with unpredictable outcomes. Conventional therapeutic options include various combinations of plasmapheresis, steroids,…
  • 2017 American Transplant Congress

    Costimulatory Blockade in Delayed Graft Function.

    J. Von Visger,1 A. Diez,1 U. Nori,1 T. Pesavento,1 R. Pelletier,2 A. Rajab,2 A. El Hinnawi,2 H. Winters.3

    1Medicine, The Ohio State University, Columbus, OH; 2Surgery, The Ohio State University, Columbus, OH; 3Pharmacy, The Ohio State University, Columbus, OH

    Background: Delayed graft function (DGF) contributes to higher risk of rejection, poorer graft survival, hospital length of stay (LOS), and other morbidities. Studies also suggest…
  • 2017 American Transplant Congress

    A Comparison of Medical Costs Among ABO-Compatible, -Incompatible, and -Minor Mismatched Living Kidney Transplantation: A Single-Center Study.

    D. Fujimori, M. Okumi, K. Ungami, H. Ishida, K. Tanabe.

    Urology, Tokyo Women's Medical University, Tokyo, Japan

    [Background]ABO-incompatible living kidney transplantation (ABO-ILKT) is considered an effective alternative to deceased kidney transplantation. Although ABO-ILKT required extra strategies and suffered extra risks across ABO…
  • 2017 American Transplant Congress

    Outcomes Following Colectomy in Liver Transplant Recipients.

    S. DiBrito, Y. Alimi, C. Haugen, I. Olorundare, D. Segev, J. Garonzik-Wang.

    Surgery, JHU, Baltimore

    Liver transplant recipients (LTR), like the general population, often require surgical procedures for non-transplant related issues. Given the need for immunosuppression and the physiologic impact…
  • 2017 American Transplant Congress

    Third Liver Transplantation, Outcomes, and the Impact of Previous Graft Survival.

    M. Barry,1 M. Gupta,2 D. Goldberg,3 M. Levine,2 D. Simpson,2 K. Olthoff,2 A. Shaked,2 P. Abt.2

    1School of Medicine, University of Pennsylvania, Philadelphia, PA; 2Surgery, Division of Transplantation, University of Pennsylvania, Philadelphia, PA; 3Medicine, Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA

    Introduction: Retransplantation with a third liver allograft is controversial with significant technical and medical challenges. National outcomes have not been described. We hypothesize that prior…
  • 2017 American Transplant Congress

    Surgical Outcomes of Pair-Watch Suturing Technique (PWST) for Duct-To-Duct Biliary Anastomosis in an Attempt to Reduce the Biliary Complications in Living Donor Liver Transplantation.

    A. Tanemura, Y. Iizawa, H. Kato, Y. Murata, N. Kuriyama, Y. Azumi, M. Kishiwada, S. Mizuno, M. Usui, H. Sakurai, S. Isaji.

    Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Japan

    Objectives:Biliary stricture is one of the major complications after living donor liver transplantation (LDLT) with duct-to-duct biliary reconstruction. To prevent biliary stenosis, we have adopted…
  • 2017 American Transplant Congress

    Eliminating False Positive Virtual Crossmatch Results for Lung Transplant Candidates by Using Multiple Antibody Testing Platforms.

    O. Timofeeva,1 M. Kashem,2 S. Geier,1 D. Grogan,2 S. Keshavamurthy,2 J. Gomez-Abraham,2 Y. Toyoda,2 F. Cordova.2

    1Department of Pathology and Laboratory of Medicine, Temple University, Lewis Katz School of Medicine, Philadelphia, PA; 2Department of Cardiovascular Surgery, Temple University, Lewis Katz School of Medicine, Philadelphia, PA

    Purpose: At present, immunologic risk for lung transplant patients is evaluated based on Virtual crossmatch (VXM) by comparing recipient's HLA antibodies detected by Single antigen…
  • 2017 American Transplant Congress

    Echinocandins in Lung Transplant Recipients (LTRs).

    Y. AlJishi,1 C. Rotstein,1 D. Kumar,1 A. Humar,1 L. Singer,2 S. Keshavjee,2 S. Husain.1

    1Transplant Infectious Diseases, University Health Network, Toronto, ON, Canada; 2Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada

    Purpose: Echinocandins are a class of antifungal drugs that have activity against Aspergillus species. However, the use of echinocandins in LTRs is not well reported.…
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