2017 American Transplant Congress
Vascularized Bone Marrow Mechanisms of Immunomodulation.
University of Maryland School of Medicine, Baltimore, MD
Introduction:Hand and face transplants containing co-transplanted bone may have improved outcomes. We have previously utilized a NHP model to demonstrate that VCA containing VBM have…2017 American Transplant Congress
Molecular Significance of Peritubular Capillaritis in Early Transplant Kidney Biopsies of Donor-Specific Antibody Negative Patients.
Montefiore Medical Center Transplant Center, Albert Einstein College of Medicine, Bronx
Background: Peritubular capillaritis (PTC) is a part of microvascular inflammation seen in antibody-mediated rejection. However, it can be observed as an isolated lesion in early…2017 American Transplant Congress
Preformed HLA Donor-Specific Antibodies Disappearance After Kidney Transplantation: Significance and Comparison with Persistent DSA.
The presence of donor-specific antibodies (DSA) increase the risk of antibody-mediated rejection (ABMR) and graft failure in kidney transplant recipients (KTR). We aimed to analyze…2017 American Transplant Congress
Outcomes of Recurrent Clostridium difficile Infection in Solid Organ Transplant Recipients.
Transplant Infectious Diseases, University Health Network, Toronto, ON, Canada
Introduction:Clostridium difficile infection(CDI) is one of the leading infectious causes among solid organ transplant (SOT) recipients. While the recurrence rate is relatively high, clinical outcomes…2017 American Transplant Congress
Identifying Risks and Screening Deceased Organ Donors in the UK for Trypanosoma cruzi .
Background: In the UK, the Advisory Committee on Microbiological Safety of Blood, Tissues and Organs recommends discretionary T. cruzi antibody screening of donors with identified…2017 American Transplant Congress
Dual Role for Caspase-3 in the Regulation of Tubular and Microvascular Damage Post-Renal Ischemia-Reperfusion Injury.
Ischemia-reperfusion injury (IRI) in renal transplant recipients is a risk factor of allograft dysfunction and reduced survival. Although tubular epithelial cells (TEC) are classically considered…2017 American Transplant Congress
Predictive Value of Serum Biomarkers of Autoimmunity for Recurrence of IgA Nephropathy After Kidney Transplantation.
The recurrence of IgA nephropathy (IgAN) after kidney transplantation is frequent and can cause graft losses. The prediction of the recurrence cannot be performed from…2017 American Transplant Congress
Acute Rejection in 6 Antigen HLA Matched Kidney Transplant Recipients: Risk Factors and Outcomes.
University of Wisconsin Health, Madison, WI
Background: Acute rejection in HLA matched kidney transplant recipients is uncommon, and the mechanisms involved are not well understood.Methods: Data from 6 antigen HLA matched…2017 American Transplant Congress
Clinical and Pathologic Characteristics of Acute Rejection After Alemtuzumab Induction in Kidney Transplant Recipients.
Background: Alemtuzumab induction (AZI) can be used for early steroid withdrawal in kidney transplant (KTx) recipients. There is evidence that AZI-induced lymphocyte depletion leads to…2017 American Transplant Congress
Infections and Outcomes in Renal Transplantation Patients Using Alemtuzumab for Induction Immunosuppression: Preliminary Results.
Surgery, University of Toledo College of Medicine, Toledo, OH
Introduction: Alemtuzumab (Ale) is a monoclonal antibody targeting CD52+ lympocytes. We sought to determine the impact of Ale immunodepletion, with steroid freedom for low risk…
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